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The impact of steatosis on liver regeneration.
Allaire M, Gilgenkrantz H. Allaire M, et al. Horm Mol Biol Clin Investig. 2018 Nov 21;41(1):/j/hmbci.2020.41.issue-1/hmbci-2018-0050/hmbci-2018-0050.xml. doi: 10.1515/hmbci-2018-0050. Horm Mol Biol Clin Investig. 2018. PMID: 30462610 Review.
Taiwan Association for the Study of the Liver-Taiwan Society of Cardiology Taiwan position statement for the management of metabolic dysfunction- associated fatty liver disease and cardiovascular diseases.
Cheng PN, Chen WJ, Hou CJ, Lin CL, Chang ML, Wang CC, Chang WT, Wang CY, Lin CY, Hung CL, Peng CY, Yu ML, Chao TH, Huang JF, Huang YH, Chen CY, Chiang CE, Lin HC, Li YH, Lin TH, Kao JH, Wang TD, Liu PY, Wu YW, Liu CJ. Cheng PN, et al. Clin Mol Hepatol. 2024 Jan;30(1):16-36. doi: 10.3350/cmh.2023.0315. Epub 2023 Oct 4. Clin Mol Hepatol. 2024. PMID: 37793641 Free PMC article. Review.
Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemia.
Chandler RJ, Di Pasquale G, Choi EY, Chang D, Smith SN, Sloan JL, Hoffmann V, Li L, Chiorini JA, Venditti CP. Chandler RJ, et al. Mol Ther Methods Clin Dev. 2023 Jun 25;30:181-190. doi: 10.1016/j.omtm.2023.06.008. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37746248 Free PMC article.
Our studies not only establish a versatile and accurate new mouse model of PA but further demonstrate that the AAV44.9 vectors may be suitable for treatment of many metabolic disorders where hepato-cardiac transduction following systemic delivery is desired, such as PA, an …
Our studies not only establish a versatile and accurate new mouse model of PA but further demonstrate that the AAV44.9 vectors may be suitab …
Prognostic significance of p16 protein in pancreatic ductal adenocarcinoma.
Iwatate Y, Hoshino I, Ishige F, Itami M, Chiba S, Arimitsu H, Yanagibashi H, Nagase H, Yokota H, Takayama W. Iwatate Y, et al. Mol Clin Oncol. 2020 Jul;13(1):83-91. doi: 10.3892/mco.2020.2047. Epub 2020 May 18. Mol Clin Oncol. 2020. PMID: 32499915 Free PMC article.
Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8.
Cabanes-Creus M, Navarro RG, Zhu E, Baltazar G, Liao SHY, Drouyer M, Amaya AK, Scott S, Nguyen LH, Westhaus A, Hebben M, Wilson LOW, Thrasher AJ, Alexander IE, Lisowski L. Cabanes-Creus M, et al. Mol Ther Methods Clin Dev. 2021 Nov 25;24:88-101. doi: 10.1016/j.omtm.2021.11.011. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2021. PMID: 34977275 Free PMC article.
Here, we report the bioengineering of a set of next-generation AAV vectors, named AAV-SYDs (where "SYD" stands for Sydney, Australia), with increased human hepato-tropism in a liver xenograft mouse model repopulated with primary human hepatocytes. ...
Here, we report the bioengineering of a set of next-generation AAV vectors, named AAV-SYDs (where "SYD" stands for Sydney, Australia), with …
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