Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains.
Sun X, Phua DYZ, Axiotakis L Jr, Smith MA, Blankman E, Gong R, Cail RC, Espinosa de Los Reyes S, Beckerle MC, Waterman CM, Alushin GM.
Sun X, et al.
Dev Cell. 2020 Nov 23;55(4):468-482.e7. doi: 10.1016/j.devcel.2020.09.022. Epub 2020 Oct 14.
Dev Cell. 2020.
PMID: 33058779
Free PMC article.
LIM domains are protein-protein interaction modules found in cytoskeletal proteins and transcriptional regulators. Here, we identify three LIM protein families (zyxin, paxillin, and FHL) whose members preferentially localize to the actin cytoskeleton in mechanically stimul …
LIM domains are protein-protein interaction modules found in cytoskeletal proteins and transcriptional regulators. Here, we identify three L …