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Year Number of Results
1993 1
1995 5
1998 2
1999 3
2000 2
2001 7
2002 4
2003 11
2004 15
2005 18
2006 20
2007 28
2008 18
2009 34
2010 31
2011 61
2012 43
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2014 75
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1,335 results

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Page 1
Stem cell-homing hydrogel-based miR-29b-5p delivery promotes cartilage regeneration by suppressing senescence in an osteoarthritis rat model.
Zhu J, Yang S, Qi Y, Gong Z, Zhang H, Liang K, Shen P, Huang YY, Zhang Z, Ye W, Yue L, Fan S, Shen S, Mikos AG, Wang X, Fang X. Zhu J, et al. Sci Adv. 2022 Apr;8(13):eabk0011. doi: 10.1126/sciadv.abk0011. Epub 2022 Mar 30. Sci Adv. 2022. PMID: 35353555 Free PMC article.
An injectable bioactive self-assembling peptide nanofiber hydrogel was applied to deliver agomir-29b-5p, which was functionalized by conjugating a stem cell-homing peptide SKPPGTSS for endogenous synovial stem cell recruitment simultaneously. ...
An injectable bioactive self-assembling peptide nanofiber hydrogel was applied to deliver agomir-29b-5p, which was functionalized by conjuga …
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal.
Li Y, Xue M, Deng X, Dong L, Nguyen LXT, Ren L, Han L, Li C, Xue J, Zhao Z, Li W, Qing Y, Shen C, Tan B, Chen Z, Leung K, Wang K, Swaminathan S, Li L, Wunderlich M, Mulloy JC, Li X, Chen H, Zhang B, Horne D, Rosen ST, Marcucci G, Xu M, Li Z, Wei M, Tian J, Shen B, Su R, Chen J. Li Y, et al. Cell Stem Cell. 2023 Aug 3;30(8):1072-1090.e10. doi: 10.1016/j.stem.2023.07.001. Cell Stem Cell. 2023. PMID: 37541212
Here, we show that Tet2 deficiency significantly facilitates leukemogenesis in various AML models (mediated by aggressive or less aggressive mutations) through promoting homing of LSCs into bone marrow (BM) niche to increase their self-renewal/proliferation. ...Collectivel …
Here, we show that Tet2 deficiency significantly facilitates leukemogenesis in various AML models (mediated by aggressive or less aggressive …
Natural killer cell homing and trafficking in tissues and tumors: from biology to application.
Ran GH, Lin YQ, Tian L, Zhang T, Yan DM, Yu JH, Deng YC. Ran GH, et al. Signal Transduct Target Ther. 2022 Jun 29;7(1):205. doi: 10.1038/s41392-022-01058-z. Signal Transduct Target Ther. 2022. PMID: 35768424 Free PMC article. Review.
Expansion of NK cells or engineered chimeric antigen receptor (CAR) NK cells ex vivo prior to adoptive transfer by using various cytokines alters the profiles of chemokine receptors, which affects the infiltration of transferred NK cells into tumor tissue. Several factors control …
Expansion of NK cells or engineered chimeric antigen receptor (CAR) NK cells ex vivo prior to adoptive transfer by using various cytokines a …
Dual modes of CRISPR-associated transposon homing.
Saito M, Ladha A, Strecker J, Faure G, Neumann E, Altae-Tran H, Macrae RK, Zhang F. Saito M, et al. Cell. 2021 Apr 29;184(9):2441-2453.e18. doi: 10.1016/j.cell.2021.03.006. Epub 2021 Mar 25. Cell. 2021. PMID: 33770501 Free PMC article.
To understand this paradox, we investigated CAST V-K and I-B systems and found two distinct modes of transposition: (1) crRNA-guided transposition and (2) CRISPR array-independent homing. We show distinct CAST systems utilize different molecular mechanisms to target their …
To understand this paradox, we investigated CAST V-K and I-B systems and found two distinct modes of transposition: (1) crRNA-guided transpo …
Cell membrane coated-nanoparticles for cancer immunotherapy.
Zeng Y, Li S, Zhang S, Wang L, Yuan H, Hu F. Zeng Y, et al. Acta Pharm Sin B. 2022 Aug;12(8):3233-3254. doi: 10.1016/j.apsb.2022.02.023. Epub 2022 Feb 28. Acta Pharm Sin B. 2022. PMID: 35967284 Free PMC article. Review.
Cell membrane-coated nanoparticles (CMCNs) inherit abundant source cell-relevant functions, including "self" markers, cross-talking with the immune system, biological targeting, and homing to specific regions. These enable them to possess preferred characteristics, includi …
Cell membrane-coated nanoparticles (CMCNs) inherit abundant source cell-relevant functions, including "self" markers, cross-talking with the …
Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy.
Zhang Y, Cai K, Li C, Guo Q, Chen Q, He X, Liu L, Zhang Y, Lu Y, Chen X, Sun T, Huang Y, Cheng J, Jiang C. Zhang Y, et al. Nano Lett. 2018 Mar 14;18(3):1908-1915. doi: 10.1021/acs.nanolett.7b05263. Epub 2018 Feb 23. Nano Lett. 2018. PMID: 29473753 Free PMC article.
Here, a macrophage-membrane-coated nanoparticle is developed for tumor-targeted chemotherapy delivery with a controlled release profile in response to tumor microenvironment stimuli. Upon fulfilling its mission of tumor homing and RES evasion, the macrophage-membrane coati …
Here, a macrophage-membrane-coated nanoparticle is developed for tumor-targeted chemotherapy delivery with a controlled release profile in r …
Vascular-homing peptides for cancer therapy.
Lu L, Qi H, Zhu J, Sun WX, Zhang B, Tang CY, Cheng Q. Lu L, et al. Biomed Pharmacother. 2017 Aug;92:187-195. doi: 10.1016/j.biopha.2017.05.054. Epub 2017 May 22. Biomed Pharmacother. 2017. PMID: 28544932 Review.
This review briefly summarizes recent studies on identification and therapeutic applications of vascular-homing peptides targeting common angiogenic markers or with unknown vascular targets in some certain types of cancers. These newly discovered vascular-homing pep …
This review briefly summarizes recent studies on identification and therapeutic applications of vascular-homing peptides targeting co …
Cancer-Erythrocyte Hybrid Membrane-Camouflaged Magnetic Nanoparticles with Enhanced Photothermal-Immunotherapy for Ovarian Cancer.
Xiong J, Wu M, Chen J, Liu Y, Chen Y, Fan G, Liu Y, Cheng J, Wang Z, Wang S, Liu Y, Zhang W. Xiong J, et al. ACS Nano. 2021 Dec 28;15(12):19756-19770. doi: 10.1021/acsnano.1c07180. Epub 2021 Dec 3. ACS Nano. 2021. PMID: 34860006
Cell-membrane-coated nanoparticles are widely studied due to their inherent cellular properties, such as immune escape and homologous homing. A cell membrane coating can also maintain the relative stability of nanoparticles during circulation in a complex blood environment …
Cell-membrane-coated nanoparticles are widely studied due to their inherent cellular properties, such as immune escape and homologous hom …
Irisin Promotes Cardiac Homing of Intravenously Delivered MSCs and Protects against Ischemic Heart Injury.
Yan W, Chen Y, Guo Y, Xia Y, Li C, Du Y, Lin C, Xu X, Qi T, Fan M, Zhang F, Hu G, Gao E, Liu R, Hai C, Tao L. Yan W, et al. Adv Sci (Weinh). 2022 Mar;9(7):e2103697. doi: 10.1002/advs.202103697. Epub 2022 Jan 17. Adv Sci (Weinh). 2022. PMID: 35038246 Free PMC article.
Here, it is found that irisin pretreatment increases the cardiac homing of adipose tissue-derived MSCs (ADSCs) administered by single and multiple intravenous injections to mice with MI/R by more than fivefold, which subsequently increases their antiapoptotic, proangiogeni …
Here, it is found that irisin pretreatment increases the cardiac homing of adipose tissue-derived MSCs (ADSCs) administered by single …
VCAM-1(+) macrophages guide the homing of HSPCs to a vascular niche.
Li D, Xue W, Li M, Dong M, Wang J, Wang X, Li X, Chen K, Zhang W, Wu S, Zhang Y, Gao L, Chen Y, Chen J, Zhou BO, Zhou Y, Yao X, Li L, Wu D, Pan W. Li D, et al. Nature. 2018 Dec;564(7734):119-124. doi: 10.1038/s41586-018-0709-7. Epub 2018 Nov 19. Nature. 2018. PMID: 30455424 Free PMC article.
After HSPCs emerge from endothelial cells within the developing dorsal aorta, homing allows the nascent cells to anchor in their niches for further expansion and differentiation(2-5). ...These cells, named 'usher cells', together with caudal venous capillaries and plexus, …
After HSPCs emerge from endothelial cells within the developing dorsal aorta, homing allows the nascent cells to anchor in their nich …
1,335 results