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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: novak i. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
Update of P2Y receptor pharmacology: IUPHAR Review 27.
Jacobson KA, Delicado EG, Gachet C, Kennedy C, von Kügelgen I, Li B, Miras-Portugal MT, Novak I, Schöneberg T, Perez-Sen R, Thor D, Wu B, Yang Z, Müller CE. Jacobson KA, et al. Among authors: novak i. Br J Pharmacol. 2020 Jun;177(11):2413-2433. doi: 10.1111/bph.15005. Epub 2020 Apr 6. Br J Pharmacol. 2020. PMID: 32037507 Free PMC article. Review.
This article reviews recent developments in P2Y receptor pharmacology (using synthetic agonists and antagonists), structure and biophysical properties (using X-ray crystallography, mutagenesis and modelling), physiological and pathophysiological roles, and present and potentially …
This article reviews recent developments in P2Y receptor pharmacology (using synthetic agonists and antagonists), structure and biophysical …
Autophagy receptors in developmental clearance of mitochondria.
Novak I, Dikic I. Novak I, et al. Autophagy. 2011 Mar;7(3):301-3. doi: 10.4161/auto.7.3.14509. Autophagy. 2011. PMID: 21206218 Free PMC article. Review.
One of the crucial homeostasis events involving autophagy is the removal of damaged or excessive mitochondria through mitophagy. Future studies on mitochondrial receptors and proteins associated with mitochondrial clearance will help us better understand the role of mitoph …
One of the crucial homeostasis events involving autophagy is the removal of damaged or excessive mitochondria through mitophagy. Future …
Mitophagy: a complex mechanism of mitochondrial removal.
Novak I. Novak I. Antioxid Redox Signal. 2012 Sep 1;17(5):794-802. doi: 10.1089/ars.2011.4407. Epub 2012 Feb 3. Antioxid Redox Signal. 2012. PMID: 22077334 Review.
The end result is either finely tuned quality control of damaged mitochondria, or mitochondrial clearance during development- induced mitophagy. FUTURE DIRECTIONS: In this article, known mechanisms and future directions for deciphering the challenge of mitophagy reg …
The end result is either finely tuned quality control of damaged mitochondria, or mitochondrial clearance during development- induced mitoph …
Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy.
Marinković M, Šprung M, Buljubašić M, Novak I. Marinković M, et al. Among authors: novak i. Oxid Med Cell Longev. 2018 Jan 31;2018:8023821. doi: 10.1155/2018/8023821. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29643976 Free PMC article. Review.
Thus, autophagy may represent a new and promising pharmacologic target for future drug development and therapeutic applications in human diseases. ...
Thus, autophagy may represent a new and promising pharmacologic target for future drug development and therapeutic applications in hu …
Molecular basis of potassium channels in pancreatic duct epithelial cells.
Hayashi M, Novak I. Hayashi M, et al. Among authors: novak i. Channels (Austin). 2013 Nov-Dec;7(6):432-41. doi: 10.4161/chan.26100. Epub 2013 Aug 20. Channels (Austin). 2013. PMID: 23962792 Free PMC article. Review.
We will give an overview of K(+) channels with respect to their electrophysiological and pharmacological characteristics and regulation, which we know from other cell types, preferably in epithelia, and, where known, their identification and functions in pancreatic ducts and in a …
We will give an overview of K(+) channels with respect to their electrophysiological and pharmacological characteristics and regulation, whi …
Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential.
Kong SC, Giannuzzo A, Novak I, Pedersen SF. Kong SC, et al. Among authors: novak i. Biochem Cell Biol. 2014 Dec;92(6):449-59. doi: 10.1139/bcb-2014-0078. Epub 2014 Aug 26. Biochem Cell Biol. 2014. PMID: 25372771 Review.
Finally, we present new data-mining analyses of acid-base transporter expression changes in PDAC and discuss essential directions for future work....
Finally, we present new data-mining analyses of acid-base transporter expression changes in PDAC and discuss essential directions for fut …
Are We Getting It Right? A Scoping Review of Outcomes Reported in Cell Therapy Clinical Studies for Cerebral Palsy.
Finch-Edmondson M, Paton MCB, Honan I, Karlsson P, Stephenson C, Chiu D, Reedman S, Griffin AR, Morgan C, Novak I. Finch-Edmondson M, et al. Among authors: novak i. J Clin Med. 2022 Dec 9;11(24):7319. doi: 10.3390/jcm11247319. J Clin Med. 2022. PMID: 36555936 Free PMC article. Review.
Notably, many outcome instruments used do not have evaluative properties and thus are not suitable for measuring change following intervention. We provide a number of recommendations to ensure that future trials generate high-quality outcome data that is aligned with the p …
Notably, many outcome instruments used do not have evaluative properties and thus are not suitable for measuring change following interventi …
Employer-sponsored occupational therapy professional development in a multicampus facility: a quality project.
Cusick A, Convey M, Novak I, McIntyre S. Cusick A, et al. Among authors: novak i. Aust Occup Ther J. 2009 Aug;56(4):229-38. doi: 10.1111/j.1440-1630.2008.00745.x. Aust Occup Ther J. 2009. PMID: 20854523 Review.
There was an assumption that personal change through PD would help attain the organisational goal of clinically competent practitioners who use evidence-based practice in a family-centred context. RECOMMENDATIONS: Future PD plans and evaluations need to explicitly address …
There was an assumption that personal change through PD would help attain the organisational goal of clinically competent practitioners who …
Concise Review: Stem Cell Interventions for People With Cerebral Palsy: Systematic Review With Meta-Analysis.
Novak I, Walker K, Hunt RW, Wallace EM, Fahey M, Badawi N. Novak I, et al. Stem Cells Transl Med. 2016 Aug;5(8):1014-25. doi: 10.5966/sctm.2015-0372. Epub 2016 May 31. Stem Cells Transl Med. 2016. PMID: 27245364 Free PMC article. Review.
A systematic review and meta-analysis summarizing and aggregating current research data may provide more conclusive evidence to inform treatment decision making and help direct future research....
A systematic review and meta-analysis summarizing and aggregating current research data may provide more conclusive evidence to inform treat …
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