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Page 1
Zyxin: a mechanotransductor to regulate gene expression.
Wang YX, Wang DY, Guo YC, Guo J. Wang YX, et al. Eur Rev Med Pharmacol Sci. 2019 Jan;23(1):413-425. doi: 10.26355/eurrev_201901_16790. Eur Rev Med Pharmacol Sci. 2019. PMID: 30657586 Free article. Review.
Growing evidence suggests that zyxin is a vital mechanotransductor to regulate the gene expression. In this review, we summarize the features of zyxin and the molecular mechanism of how zyxin participate in the cellular activity. ...
Growing evidence suggests that zyxin is a vital mechanotransductor to regulate the gene expression. In this review, we summarize the …
Zyxin Inhibits the Proliferation, Migration, and Invasion of Osteosarcoma via Rap1-Mediated Inhibition of the MEK/ERK Signaling Pathway.
Wei Z, Xia K, Zhou B, Zheng D, Guo W. Wei Z, et al. Biomedicines. 2023 Aug 21;11(8):2314. doi: 10.3390/biomedicines11082314. Biomedicines. 2023. PMID: 37626810 Free PMC article.
Zyxin (ZYX) is an actin-interacting protein with unknown biological functions in patients with osteosarcoma. ...
Zyxin (ZYX) is an actin-interacting protein with unknown biological functions in patients with osteosarcoma. ...
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Zhao Y, Yue S, Zhou X, Guo J, Ma S, Chen Q. Zhao Y, et al. J Biol Chem. 2022 Apr;298(4):101776. doi: 10.1016/j.jbc.2022.101776. Epub 2022 Feb 25. J Biol Chem. 2022. PMID: 35227760 Free PMC article.
Zyxin is a zinc-binding phosphoprotein known to regulate cell migration, adhesion, and cell survival. ...Furthermore, we found that 14-3-3gamma could promote the nuclear localization of Zyxin after Ser-169 O-GlcNAcylation by affecting the function of the N-terminal …
Zyxin is a zinc-binding phosphoprotein known to regulate cell migration, adhesion, and cell survival. ...Furthermore, we found that 1 …
miR-16-5p Is a Novel Mediator of Venous Smooth Muscle Phenotypic Switching.
Zhang D, Shi J, Liang G, Liu D, Zhang J, Pan S, Lu Y, Wu Q, Gong C, Guo Y. Zhang D, et al. J Cardiovasc Transl Res. 2022 Aug;15(4):876-889. doi: 10.1007/s12265-022-10208-1. Epub 2022 May 2. J Cardiovasc Transl Res. 2022. PMID: 35501542 Free PMC article.
Furthermore, miR-16-5p overexpression increased SMCs differentiation marker expression while suppressing HSVSMCs proliferation and migration and drastically inhibiting neointimal development in vein grafts. The miR-16-5p inhibited zyxin expression, which was necessary for …
Furthermore, miR-16-5p overexpression increased SMCs differentiation marker expression while suppressing HSVSMCs proliferation and migration …
Predictive value of serum proteomic biomarkers for noise-induced hearing loss.
Lun Y, Chen J, Lu P, Yuan H, Ma P, Wang W, Liang R, Li S, Gao W, Ding X, Wang Z, Guo J, Lu L. Lun Y, et al. Environ Sci Pollut Res Int. 2023 Sep;30(43):96827-96839. doi: 10.1007/s11356-023-29294-y. Epub 2023 Aug 15. Environ Sci Pollut Res Int. 2023. PMID: 37582891
Then, according to the results, we predicted that caldesmon (CALD1), myocilin (MYOC), zyxin (ZYX), creatine kinase M-type (CKM), insulin-like growth factor-binding protein 2 (IGFBP2), complement factor H-related protein 4 (CFHR4), prenylcysteine oxidase 1 (PCYOX1), heat sh …
Then, according to the results, we predicted that caldesmon (CALD1), myocilin (MYOC), zyxin (ZYX), creatine kinase M-type (CKM), insu …
Perfluorooctanoic acid affects endocytosis involving clathrin light chain A and microRNA-133b-3p in mouse testes.
Lu Y, Wang J, Guo X, Yan S, Dai J. Lu Y, et al. Toxicol Appl Pharmacol. 2017 Mar 1;318:41-48. doi: 10.1016/j.taap.2017.01.014. Epub 2017 Jan 24. Toxicol Appl Pharmacol. 2017. PMID: 28126411
Endocytosis-related genes were selected for qPCR analysis, with many found to be significantly changed after PFOA treatment, including epidermal growth factor receptor pathway substrate 8 (Eps8), Eps15, cortactin, cofilin, espin, vinculin, and zyxin. We further predicted t …
Endocytosis-related genes were selected for qPCR analysis, with many found to be significantly changed after PFOA treatment, including epide …
Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer.
Wang W, Huper G, Guo Y, Murphy SK, Olson JA Jr, Marks JR. Wang W, et al. Oncogene. 2005 Apr 14;24(16):2705-14. doi: 10.1038/sj.onc.1208464. Oncogene. 2005. PMID: 15735726
Northern blotting for five of these genes (alpha-Catenin, DTR, FYN, GADD45a, and Zyxin) verified the array results. Further analysis of one of these genes, GADD45a, showed that 5-AzaC induced expression in five additional breast cancer cell lines with little or no inductio …
Northern blotting for five of these genes (alpha-Catenin, DTR, FYN, GADD45a, and Zyxin) verified the array results. Further analysis …
Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals.
Guo WH, Wang YL. Guo WH, et al. Mol Biol Cell. 2007 Nov;18(11):4519-27. doi: 10.1091/mbc.e07-06-0582. Epub 2007 Sep 5. Mol Biol Cell. 2007. PMID: 17804814 Free PMC article.
Using live cell fluorescence imaging, we found that actin filaments, in association with a number of focal adhesion proteins, including zyxin and vasodilator-stimulated phosphoprotein, undergo retrograde fluxes at focal adhesions in the lamella region. ...
Using live cell fluorescence imaging, we found that actin filaments, in association with a number of focal adhesion proteins, including z …