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Zyxin promotes hepatocellular carcinoma progression via the activation of AKT/mTOR signaling pathway.
Cai T, Bai J, Tan P, Huang Z, Liu C, Wu Z, Cheng Y, Li T, Chen Y, Ruan J, Gao L, DU Y, Fu W. Cai T, et al. Oncol Res. 2023 Jul 21;31(5):805-817. doi: 10.32604/or.2023.029549. eCollection 2023. Oncol Res. 2023. PMID: 37547758 Free PMC article.
The aim of this study was to investigate the role and specific mechanism of the actin-interacting protein zyxin (ZYX) in HCC. We found that the expression of ZYX was significantly higher in HCC tissues compared to that in normal liver tissues. ...
The aim of this study was to investigate the role and specific mechanism of the actin-interacting protein zyxin (ZYX) in HCC. We foun …
Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-beta signalling pathways.
Ma B, Cheng H, Gao R, Mu C, Chen L, Wu S, Chen Q, Zhu Y. Ma B, et al. Nat Commun. 2016 Mar 31;7:11123. doi: 10.1038/ncomms11123. Nat Commun. 2016. PMID: 27030211 Free PMC article.
Depletion of Zyxin impairs the capability of cell migration, proliferation and tumourigenesis in a xenograft model. Zyxin is upregulated in human breast cancer and positively correlates with histological stages and metastasis. ...
Depletion of Zyxin impairs the capability of cell migration, proliferation and tumourigenesis in a xenograft model. Zyxin is u …
Variants of Focal Adhesion Scaffold Genes Cause Thoracic Aortic Aneurysm.
Li Y, Gao S, Han Y, Song L, Kong Y, Jiao Y, Huang S, Du J, Li Y. Li Y, et al. Circ Res. 2021 Jan 8;128(1):8-23. doi: 10.1161/CIRCRESAHA.120.317361. Epub 2020 Oct 23. Circ Res. 2021. PMID: 33092471 Free article.
Interestingly, suspected functional variants of other focal adhesion scaffold genes, including TLN1 (Talin-1) and ZYX (zyxin), were also significantly enriched in patients with iTAA; moreover, their knockdown resulted in decreased contractility of vascular smooth muscle ce …
Interestingly, suspected functional variants of other focal adhesion scaffold genes, including TLN1 (Talin-1) and ZYX (zyxin), were a …
TRIP6 a potential diagnostic marker for colorectal cancer with glycolysis and immune infiltration association.
Liu XS, Chen YX, Wan HB, Wang YL, Wang YY, Gao Y, Wu LB, Pei ZJ. Liu XS, et al. Sci Rep. 2024 Feb 19;14(1):4042. doi: 10.1038/s41598-024-54670-0. Sci Rep. 2024. PMID: 38369589 Free PMC article.
Thyroid hormone receptor interactor 6 (TRIP6) it is an adaptor protein belonging to the zyxin family of LIM proteins, participating in signaling events through interactions with various molecules. ...
Thyroid hormone receptor interactor 6 (TRIP6) it is an adaptor protein belonging to the zyxin family of LIM proteins, participating i …
Cooperation between myofibril growth and costamere maturation in human cardiomyocytes.
Shi H, Wang C, Gao BZ, Henderson JH, Ma Z. Shi H, et al. Front Bioeng Biotechnol. 2022 Nov 1;10:1049523. doi: 10.3389/fbioe.2022.1049523. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 36394013 Free PMC article.
However, how costamere maturation cooperates with myofibril growth is still underexplored. In this work, we analyzed zyxin (costameres), alpha-actinin (Z-lines) and myomesin (M-lines) to track the behaviors of costameres and myofibrils within the cardiomyocytes derived fro …
However, how costamere maturation cooperates with myofibril growth is still underexplored. In this work, we analyzed zyxin (costamere …
Predictive value of serum proteomic biomarkers for noise-induced hearing loss.
Lun Y, Chen J, Lu P, Yuan H, Ma P, Wang W, Liang R, Li S, Gao W, Ding X, Wang Z, Guo J, Lu L. Lun Y, et al. Environ Sci Pollut Res Int. 2023 Sep;30(43):96827-96839. doi: 10.1007/s11356-023-29294-y. Epub 2023 Aug 15. Environ Sci Pollut Res Int. 2023. PMID: 37582891
Then, according to the results, we predicted that caldesmon (CALD1), myocilin (MYOC), zyxin (ZYX), creatine kinase M-type (CKM), insulin-like growth factor-binding protein 2 (IGFBP2), complement factor H-related protein 4 (CFHR4), prenylcysteine oxidase 1 (PCYOX1), heat sh …
Then, according to the results, we predicted that caldesmon (CALD1), myocilin (MYOC), zyxin (ZYX), creatine kinase M-type (CKM), insu …
Cortical actin regulation modulates vascular contractility and compliance in veins.
Saphirstein RJ, Gao YZ, Lin QQ, Morgan KG. Saphirstein RJ, et al. J Physiol. 2015 Sep 1;593(17):3929-41. doi: 10.1113/JP270845. Epub 2015 Jul 26. J Physiol. 2015. PMID: 26096914 Free PMC article.
No detectable change in focal adhesion size, measured by immunofluorescence of FAK and zyxin, accompanies the PE-induced changes in cortical stiffness. ...
No detectable change in focal adhesion size, measured by immunofluorescence of FAK and zyxin, accompanies the PE-induced changes in c …