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The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z. Ai J, et al. Free Radic Biol Med. 2021 Jan;162:181-190. doi: 10.1016/j.freeradbiomed.2020.10.003. Epub 2020 Oct 22. Free Radic Biol Med. 2021. PMID: 33131696
miR-421 up-regulation by the oleanolic acid derivative K73-03 regulates epigenetically SPINK1 transcription in pancreatic cancer cells leading to metabolic changes and enhanced apoptosis.
Shopit A, Li X, Tang Z, Awsh M, Shobet L, Niu M, Wang H, Mousa H, Alshwmi M, Tesfaldet T, Gamallat Y, Li H, Chu P, Ahmad N, Jamalat Y, Ai J, Qaed E, Almoiliqy M, Wang S, Tang Z. Shopit A, et al. Pharmacol Res. 2020 Nov;161:105130. doi: 10.1016/j.phrs.2020.105130. Epub 2020 Aug 17. Pharmacol Res. 2020. PMID: 32818653
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