Case of Childhood Absence Epilepsy with Focal Spikes

World Neurosurg. 2019 Jun:126:601-604. doi: 10.1016/j.wneu.2019.02.225. Epub 2019 Mar 14.

Abstract

Background: Childhood absence epilepsy is a common generalized epilepsy syndrome characterized by childhood onset of frequent sporadic absence seizures. During onset, the electroencephalogram exhibits bilateral, symmetric, and synchronous discharges of approximately 3 Hz of generalized spike-and-wave complexes. Focal spikes are often found in children with focal epilepsy but are not common in absence epilepsy.

Case description: In the case patient, focal spikes were observed during active onset of absence epilepsy and at 5 years after the first hospital visit, at which time absence epilepsy was controlled and medication was withdrawn without focal seizure attack in the interim.

Conclusions: This case demonstrates that focal spikes associated with childhood absence epilepsy do not require specific treatment in the absence of focal seizures.

Keywords: Childhood absence epilepsy; Coexistence; Electroencephalogram; Epilepsy; Rolandic spikes.

Publication types

  • Case Reports

MeSH terms

  • Action Potentials
  • Anticonvulsants / therapeutic use
  • Child
  • Drug Substitution
  • Electroencephalography
  • Epilepsy, Absence / diagnostic imaging
  • Epilepsy, Absence / drug therapy
  • Epilepsy, Absence / physiopathology*
  • Follow-Up Studies
  • Humans
  • Lamotrigine / therapeutic use
  • Magnetic Resonance Imaging
  • Male
  • Neuroimaging
  • Sleep Disorders, Intrinsic / physiopathology
  • Valproic Acid / therapeutic use
  • Video Recording

Substances

  • Anticonvulsants
  • Valproic Acid
  • Lamotrigine