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Did you mean yusuf ko (7 results)?
Highly specific σ2R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response.
Yousuf MS, Sahn JJ, Yang H, David ET, Shiers S, Moreno MM, Iketem J, Royer DM, Garcia CD, Zhang J, Hong VM, Mian SM, Ahmad A, Kolber BJ, Liebl DJ, Martin SF, Price TJ. Yousuf MS, et al. bioRxiv [Preprint]. 2023 Oct 17:2023.04.11.536439. doi: 10.1101/2023.04.11.536439. bioRxiv. 2023. PMID: 37090527 Free PMC article. Updated. Preprint.
We sought to understand this unique anti-neuropathic pain effect by addressing two key questions: do these sigma(2)R/TMEM97 compounds act selectively via the receptor, and what is their downstream mechanism on nociceptive neurons? Using male and female conventional knockout (K …
We sought to understand this unique anti-neuropathic pain effect by addressing two key questions: do these sigma(2)R/TMEM97 compounds act se …
PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells.
Rah B, ur Rasool R, Nayak D, Yousuf SK, Mukherjee D, Kumar LD, Goswami A. Rah B, et al. Autophagy. 2015;11(2):314-31. doi: 10.1080/15548627.2015.1017182. Autophagy. 2015. PMID: 25803782 Free PMC article.
This inhibition of BECN1 in CaP cells, leading to the disruption of the BCL2-BECN1 interaction by overexpressed PAWR has not been reported so far. Third, we provide evidence that pawr-KO MEFs exhibited abundant autophagy signs even at toxic concentrations of 3-AWA undersco …
This inhibition of BECN1 in CaP cells, leading to the disruption of the BCL2-BECN1 interaction by overexpressed PAWR has not been reported s …