yau yi lau - Search Results

Year	Number of Results
2002	3
2003	1
2004	2
2007	2
2008	1
2024	0

1

Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor.

Zhao G, Souers AJ, Voorbach M, Falls HD, Droz B, Brodjian S, Lau YY, Iyengar RR, Gao J, Judd AS, Wagaw SH, Ravn MM, Engstrom KM, Lynch JK, Mulhern MM, Freeman J, Dayton BD, Wang X, Grihalde N, Fry D, Beno DW, Marsh KC, Su Z, Diaz GJ, Collins CA, Sham H, Reilly RM, Brune ME, Kym PR. Zhao G, et al. Among authors: lau yy. J Med Chem. 2008 Feb 14;51(3):380-3. doi: 10.1021/jm7013887. Epub 2008 Jan 10. J Med Chem. 2008. PMID: 18183944

2

A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction.

Cui X, Palamanda J, Norton L, Thomas A, Lau YY, White RE, Cheng KC. Cui X, et al. Among authors: lau yy. J Pharmacol Toxicol Methods. 2002 May-Jun;47(3):143-51. doi: 10.1016/S1056-8719(02)00222-8. J Pharmacol Toxicol Methods. 2002. PMID: 12628305

3

Solid phase extraction as a faster alternative to HPLC: application to MS analysis of metabolic stability samples.

Inman BL, Chovan LE, Dandliker PJ, Lau YY. Inman BL, et al. Among authors: lau yy. J Pharm Sci. 2007 Jun;96(6):1619-24. doi: 10.1002/jps.20788. J Pharm Sci. 2007. PMID: 17094126

4

Evaluation of a novel in vitro Caco-2 hepatocyte hybrid system for predicting in vivo oral bioavailability.

Lau YY, Chen YH, Liu TT, Li C, Cui X, White RE, Cheng KC. Lau YY, et al. Drug Metab Dispos. 2004 Sep;32(9):937-42. Drug Metab Dispos. 2004. PMID: 15319334

5

Development of a novel in vitro model to predict hepatic clearance using fresh, cryopreserved, and sandwich-cultured hepatocytes.

Lau YY, Sapidou E, Cui X, White RE, Cheng KC. Lau YY, et al. Drug Metab Dispos. 2002 Dec;30(12):1446-54. doi: 10.1124/dmd.30.12.1446. Drug Metab Dispos. 2002. PMID: 12433818

6

Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists.

Wang X, Kolasa T, El Kouhen OF, Chovan LE, Black-Shaefer CL, Wagenaar FL, Garton JA, Moreland RB, Honore P, Lau YY, Dandliker PJ, Brioni JD, Stewart AO. Wang X, et al. Among authors: lau yy. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4303-7. doi: 10.1016/j.bmcl.2007.05.028. Epub 2007 May 16. Bioorg Med Chem Lett. 2007. PMID: 17532216

7

Semi-automated determination of plasma stability of drug discovery compounds using liquid chromatography-tandem mass spectrometry.

Wang G, Hsieh Y, Lau Y, Cheng KC, Ng K, Korfmacher WA, White RE. Wang G, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Nov 25;780(2):451-7. doi: 10.1016/s1570-0232(02)00467-1. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 12401373

8

Semi-automatic high-throughput determination of plasma protein binding using a 96-well plate filtrate assembly and fast liquid chromatography-tandem mass spectrometry.

Fung EN, Chen YH, Lau YY. Fung EN, et al. Among authors: lau yy. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Oct 5;795(2):187-94. doi: 10.1016/s1570-0232(03)00564-6. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 14522023

9

Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.

Chovan LE, Black-Schaefer C, Dandliker PJ, Lau YY. Chovan LE, et al. Among authors: lau yy. Rapid Commun Mass Spectrom. 2004;18(24):3105-12. doi: 10.1002/rcm.1735. Rapid Commun Mass Spectrom. 2004. PMID: 15565734

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