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Did you mean xie qiong ni (2 results)?
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Ma H, Cui J, Liu Z, Fang W, Lu S, Cao S, Zhang Y, Chen JA, Lu L, Xie Q, Wang Y, Huang Y, Li K, Tong H, Huang J, Lu W. Ma H, et al. Among authors: xie q. Oncogene. 2023 Nov;42(45):3331-3343. doi: 10.1038/s41388-023-02848-7. Epub 2023 Sep 26. Oncogene. 2023. PMID: 37752234
Herein, we showed that FLT3-ITD mutant (FLT3-ITD(+)) AML cells were susceptible toward inhibitors of DHODH, a rate-limiting enzyme of de novo pyrimidine biosynthesis. Genetic and pharmacological blockade of DHODH triggered downregulation of FLT3-ITD protein, subsequently s …
Herein, we showed that FLT3-ITD mutant (FLT3-ITD(+)) AML cells were susceptible toward inhibitors of DHODH, a rate-limiting enzyme of de nov …
High-coverage proteomics reveals methionine auxotrophy in Deinococcus radiodurans.
Zhou Y, Shen P, Lan Q, Deng C, Zhang Y, Li Y, Wei W, Wang Y, Su N, He F, Xie Q, Lyu Z, Yang D, Xu P. Zhou Y, et al. Among authors: xie q. Proteomics. 2017 Jul;17(13-14). doi: 10.1002/pmic.201700072. Proteomics. 2017. PMID: 28608649
Comparison of the identified proteins to the key enzymes in amino acid biosyntheses from KEGG database showed the methionine biosynthesis module is incomplete while other amino acid biosynthesis modules are complete, which indicated methionine auxotrophy in D. radio …
Comparison of the identified proteins to the key enzymes in amino acid biosyntheses from KEGG database showed the methionine biosynthesis …