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A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy.
McKenzie LK, Flamme M, Felder PS, Karges J, Bonhomme F, Gandioso A, Malosse C, Gasser G, Hollenstein M. McKenzie LK, et al. RSC Chem Biol. 2021 Nov 2;3(1):85-95. doi: 10.1039/d1cb00146a. eCollection 2022 Jan 5. RSC Chem Biol. 2021. PMID: 35128412 Free PMC article.
Here we present the first example of direct conjugation of a Ru(ii) polypyridyl complex-based PS to an aptamer and an assessment of its in vitro cancer cell specific photosensitization including discussion of the challenges faced....
Here we present the first example of direct conjugation of a Ru(ii) polypyridyl complex-based PS to an aptamer and an assessment of its in …
BotCl, the First Chlorotoxin-like Peptide Inhibiting Newcastle Disease Virus: The Emergence of a New Scorpion Venom AMPs Family.
Jlassi A, Mekni-Toujani M, Ferchichi A, Gharsallah C, Malosse C, Chamot-Rooke J, ElAyeb M, Ghram A, Srairi-Abid N, Daoud S. Jlassi A, et al. Molecules. 2023 May 26;28(11):4355. doi: 10.3390/molecules28114355. Molecules. 2023. PMID: 37298831 Free PMC article.
In this study, we have screened fractions of Buthus occitanus tunetanus (Bot) scorpion venom and isolated the first scorpion peptide inhibiting the NDV multiplication. It showed a dose dependent effect on NDV growth in vitro, with an IC(50) of 0.69 M, and a low cytotoxicit …
In this study, we have screened fractions of Buthus occitanus tunetanus (Bot) scorpion venom and isolated the first scorpion peptide inhibit …