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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1906 1
1907 2
1909 1
1910 1
1911 5
1912 3
1913 6
1914 8
1916 6
1917 5
1919 1
1920 2
1921 2
1922 8
1923 5
1924 4
1925 1
1926 9
1927 2
1928 8
1929 3
1930 4
1931 4
1932 8
1933 6
1934 3
1935 2
1936 7
1937 4
1938 3
1939 9
1940 6
1941 6
1942 5
1943 1
1944 1
1945 7
1946 24
1947 46
1948 51
1949 40
1950 60
1951 64
1952 78
1953 89
1954 131
1955 121
1956 133
1957 152
1958 194
1959 217
1960 223
1961 261
1962 317
1963 365
1964 895
1965 4525
1966 4433
1967 2366
1968 1988
1969 2545
1970 2733
1971 3281
1972 3757
1973 4084
1974 4446
1975 6326
1976 6350
1977 7005
1978 7216
1979 7318
1980 8192
1981 8652
1982 9522
1983 10552
1984 11832
1985 12990
1986 13251
1987 13829
1988 14562
1989 16747
1990 17971
1991 18064
1992 18536
1993 19613
1994 19544
1995 19938
1996 19317
1997 19663
1998 20148
1999 20697
2000 21355
2001 21613
2002 22262
2003 23250
2004 24783
2005 26640
2006 27838
2007 28614
2008 29572
2009 30755
2010 33865
2011 35814
2012 38538
2013 40516
2014 41700
2015 43237
2016 44066
2017 45757
2018 47340
2019 50031
2020 54016
2021 55658
2022 52751
2023 49839
2024 19662

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1,193,606 results

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Page 1
Cell Sources for Human In vitro Bone Models.
Ansari S, Ito K, Hofmann S. Ansari S, et al. Curr Osteoporos Rep. 2021 Feb;19(1):88-100. doi: 10.1007/s11914-020-00648-6. Epub 2021 Jan 15. Curr Osteoporos Rep. 2021. PMID: 33447910 Free PMC article. Review.
Due to the heterogeneity of cells among patients, patient's own cells are needed to be obtained, ideally, from one single cell source. ...Recent studies on these cell sources have shown no significant differences between isolated progenitor cells
Due to the heterogeneity of cells among patients, patient's own cells are needed to be obtained, ideally, from one single c
Modeled vascular microenvironments: immune-endothelial cell interactions in vitro.
Silberman J, Jha A, Ryan H, Abbate T, Moore E. Silberman J, et al. Drug Deliv Transl Res. 2021 Dec;11(6):2482-2495. doi: 10.1007/s13346-021-00970-1. Epub 2021 Apr 1. Drug Deliv Transl Res. 2021. PMID: 33797034 Review.
In vitro studies allow for enhanced observation of cell behavior, control over the mimicked microenvironment, and the ability to use human cells. ...Specific immune cells such as monocytes, macrophages, neutrophils, and T cells influence endothe …
In vitro studies allow for enhanced observation of cell behavior, control over the mimicked microenvironment, and the ability …
Cell sources for in vitro human liver cell culture models.
Zeilinger K, Freyer N, Damm G, Seehofer D, Knöspel F. Zeilinger K, et al. Exp Biol Med (Maywood). 2016 Sep;241(15):1684-98. doi: 10.1177/1535370216657448. Epub 2016 Jul 5. Exp Biol Med (Maywood). 2016. PMID: 27385595 Free PMC article. Review.
In vitro liver cell culture models are gaining increasing importance in pharmacological and toxicological research. ...This review gives an overview of the major human cell sources under investigation for in vitro liver cell culture models, incl …
In vitro liver cell culture models are gaining increasing importance in pharmacological and toxicological research. ...This re …
Germ Cell Derivation from Pluripotent Stem Cells for Understanding In Vitro Gametogenesis.
Hong TK, Song JH, Lee SB, Do JT. Hong TK, et al. Cells. 2021 Jul 26;10(8):1889. doi: 10.3390/cells10081889. Cells. 2021. PMID: 34440657 Free PMC article. Review.
In vitro gametogenesis is a promising technology to overcome infertility, particularly germ cell aplasia. Early germ cells, such as primordial germ cells, can be relatively easily derived from pluripotent stem cells (PSCs); however, further prog …
In vitro gametogenesis is a promising technology to overcome infertility, particularly germ cell aplasia. Early germ cells
Strategies for immortalization of primary hepatocytes.
Ramboer E, De Craene B, De Kock J, Vanhaecke T, Berx G, Rogiers V, Vinken M. Ramboer E, et al. J Hepatol. 2014 Oct;61(4):925-43. doi: 10.1016/j.jhep.2014.05.046. Epub 2014 Jun 6. J Hepatol. 2014. PMID: 24911463 Free PMC article. Review.
However, in vitro cell growth can be boosted by immortalization of hepatocytes. Well-defined immortalization genes can be artificially overexpressed in hepatocytes or the cells can be conditionally immortalized leading to controlled cell proliferation. …
However, in vitro cell growth can be boosted by immortalization of hepatocytes. Well-defined immortalization genes can be arti …
Temporal establishment of neural cell identity in vivo and in vitro.
Yuen SM, Kwok HF. Yuen SM, et al. J Tissue Eng Regen Med. 2017 Sep;11(9):2582-2589. doi: 10.1002/term.2158. Epub 2016 Apr 6. J Tissue Eng Regen Med. 2017. PMID: 27061786 Review.
Traditionally, lineage-specific progenitors are generated in vitro from pluripotent cells, after which they may be channeled into more mature cell types in a stage-specific manner, which is similar to the way cells behave during development. ...Cell
Traditionally, lineage-specific progenitors are generated in vitro from pluripotent cells, after which they may be channeled i …
In Vitro T-Cell Generation From Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination.
Smith MJ, Webber BR, Mohtashami M, Stefanski HE, Zúñiga-Pflücker JC, Blazar BR. Smith MJ, et al. Stem Cells. 2015 Nov;33(11):3174-80. doi: 10.1002/stem.2115. Epub 2015 Aug 11. Stem Cells. 2015. PMID: 26227158 Free PMC article. Review.
T-cell differentiation in vivo is a complex process requiring tightly regulated signals; providing the correct signals in vitro to induce T-cell lineage commitment followed by their development into mature, functional, single positive T cells, is simil …
T-cell differentiation in vivo is a complex process requiring tightly regulated signals; providing the correct signals in vitro
Generation of Murine T Cell Effector Populations In Vitro.
Vacchio MS. Vacchio MS. Methods Mol Biol. 2023;2580:173-186. doi: 10.1007/978-1-0716-2740-2_10. Methods Mol Biol. 2023. PMID: 36374457
Expansion of T cell subsets in vitro is a valuable tool for exploration of effector function and differentiation. Here we provide protocols for in vitro differentiation of CD4 and CD8 T cell subsets from naive T cells for functional studies....
Expansion of T cell subsets in vitro is a valuable tool for exploration of effector function and differentiation. Here we prov …
Liver fibrosis in vitro: cell culture models and precision-cut liver slices.
Van de Bovenkamp M, Groothuis GM, Meijer DK, Olinga P. Van de Bovenkamp M, et al. Toxicol In Vitro. 2007 Jun;21(4):545-57. doi: 10.1016/j.tiv.2006.12.009. Epub 2007 Jan 3. Toxicol In Vitro. 2007. PMID: 17289342 Review.
Both primary cells and cell lines as well as the use of different culture matrices and co-culture models are discussed. ...By combining the use of the different cell and tissue culture models, the mechanisms underlying multicellular fibrosis development can b …
Both primary cells and cell lines as well as the use of different culture matrices and co-culture models are discussed. ...By …
A review of human cell radiosensitivity in vitro.
Deschavanne PJ, Fertil B. Deschavanne PJ, et al. Int J Radiat Oncol Biol Phys. 1996 Jan 1;34(1):251-66. doi: 10.1016/0360-3016(95)02029-2. Int J Radiat Oncol Biol Phys. 1996. PMID: 12118559 Review.
In particular, the cell type is not a discriminating factor when cells are studied in agar. ...The use of feeder cells narrows the range of radiosensitivity of human cells. For cells irradiated as monolayer, it was possible to build a scale of r …
In particular, the cell type is not a discriminating factor when cells are studied in agar. ...The use of feeder cells
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