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Year Number of Results
1987 1
1989 2
1990 2
1991 2
1992 1
1993 6
1994 5
1995 6
1996 6
1997 5
1998 10
1999 8
2000 15
2001 16
2002 26
2003 17
2004 32
2005 39
2006 57
2007 47
2008 57
2009 65
2010 61
2011 56
2012 56
2013 81
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2024 90

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2,220 results

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Page 1
The Sequence Alignment/Map format and SAMtools.
Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, Marth G, Abecasis G, Durbin R; 1000 Genome Project Data Processing Subgroup. Li H, et al. Bioinformatics. 2009 Aug 15;25(16):2078-9. doi: 10.1093/bioinformatics/btp352. Epub 2009 Jun 8. Bioinformatics. 2009. PMID: 19505943 Free PMC article.
SUMMARY: The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms. ...SAMtools implements various utilities for …
SUMMARY: The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequence …
Malnutrition and Gut Microbiota in Children.
Iddrisu I, Monteagudo-Mera A, Poveda C, Pyle S, Shahzad M, Andrews S, Walton GE. Iddrisu I, et al. Nutrients. 2021 Aug 8;13(8):2727. doi: 10.3390/nu13082727. Nutrients. 2021. PMID: 34444887 Free PMC article. Review.
Diarrhoea leads to malabsorption of essential nutrients and reduced energy availability resulting in weight loss, which can lead to malnutrition. Alterations in gut microbiota of severe acute malnourished (SAM) children include increased Proteobacteria and decreased Bacter …
Diarrhoea leads to malabsorption of essential nutrients and reduced energy availability resulting in weight loss, which can lead to malnutri …
S-adenosyl-methionine-dependent methyltransferases: highly versatile enzymes in biocatalysis, biosynthesis and other biotechnological applications.
Struck AW, Thompson ML, Wong LS, Micklefield J. Struck AW, et al. Chembiochem. 2012 Dec 21;13(18):2642-55. doi: 10.1002/cbic.201200556. Epub 2012 Nov 23. Chembiochem. 2012. PMID: 23180741 Review.
The methylation process thus has important implications in various disease processes and applications in industrial chemical processing. This methyl transfer is catalysed by SAM-dependent methyltransferases (MTases), which are by far the largest groups of SAM-depend …
The methylation process thus has important implications in various disease processes and applications in industrial chemical processing. Thi …
METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation.
Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. Pandolfini L, et al. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25. Mol Cell. 2019. PMID: 31031083 Free PMC article.
Methyltransferases: Functions and Applications.
Abdelraheem E, Thair B, Varela RF, Jockmann E, Popadić D, Hailes HC, Ward JM, Iribarren AM, Lewkowicz ES, Andexer JN, Hagedoorn PL, Hanefeld U. Abdelraheem E, et al. Chembiochem. 2022 Sep 16;23(18):e202200212. doi: 10.1002/cbic.202200212. Epub 2022 Jul 5. Chembiochem. 2022. PMID: 35691829 Free PMC article. Review.
In this review the current state-of-the-art of S-adenosylmethionine (SAM)-dependent methyltransferases and SAM are evaluated. Their structural classification and diversity is introduced and key mechanistic aspects presented which are then detailed further. Then, cat …
In this review the current state-of-the-art of S-adenosylmethionine (SAM)-dependent methyltransferases and SAM are evaluated. …
Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection.
Lou G, Anderluzzi G, Schmidt ST, Woods S, Gallorini S, Brazzoli M, Giusti F, Ferlenghi I, Johnson RN, Roberts CW, O'Hagan DT, Baudner BC, Perrie Y. Lou G, et al. J Control Release. 2020 Sep 10;325:370-379. doi: 10.1016/j.jconrel.2020.06.027. Epub 2020 Jul 1. J Control Release. 2020. PMID: 32619745 Free article.
To protect the SAM from degradation and achieve efficient delivery, lipid nanoparticles (LNPs), particularly those based on ionizable amino-lipids, are commonly adopted. ...Both the cLNP formulations and the iLNPs induced strong humoral and cellular-mediated immune respons …
To protect the SAM from degradation and achieve efficient delivery, lipid nanoparticles (LNPs), particularly those based on ionizable …
SAM syndrome is characterized by extensive phenotypic heterogeneity.
Taiber S, Samuelov L, Mohamad J, Barak EC, Sarig O, Shalev SA, Lestringant G, Sprecher E. Taiber S, et al. Exp Dermatol. 2018 Jul;27(7):787-790. doi: 10.1111/exd.13551. Exp Dermatol. 2018. PMID: 29604126 Review.
Severe skin dermatitis, multiple allergies and metabolic wasting (SAM) syndrome is a rare life-threatening inherited condition caused by bi-allelic mutations in DSG1 encoding desmoglein 1. ...Whole exome and direct sequencing were used to identify SAM syndrome-causi …
Severe skin dermatitis, multiple allergies and metabolic wasting (SAM) syndrome is a rare life-threatening inherited condition caused …
VISUAL VIGNETTE.
Almazrouei RA, Sam AH, Meeran K, Palazzo F. Almazrouei RA, et al. Endocr Pract. 2019 Aug;25(8):862. doi: 10.4158/EP-2018-0579. Epub 2019 Jan 18. Endocr Pract. 2019. PMID: 30657364 No abstract available.
A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA.
Tang DJ, Du X, Shi Q, Zhang JL, He YP, Chen YM, Ming Z, Wang D, Zhong WY, Liang YW, Liu JY, Huang JM, Zhong YS, An SQ, Gu H, Tang JL. Tang DJ, et al. Nat Commun. 2020 Jun 3;11(1):2794. doi: 10.1038/s41467-020-16417-z. Nat Commun. 2020. PMID: 32493973 Free PMC article.
In vitro and in vivo experiments show that SAM-I(Xcc) controls the met operon primarily at the translational level in response to cellular S-adenosylmethionine (SAM) levels. ...This SAM-I riboswitch appears to be highly conserved in Xanthomonas species....
In vitro and in vivo experiments show that SAM-I(Xcc) controls the met operon primarily at the translational level in response to cel …
3-Deazaadenosine keeps senescence at bay.
Guerrero A, Gil J. Guerrero A, et al. Aging (Albany NY). 2023 Mar 24;15(7):2369-2370. doi: 10.18632/aging.204625. Epub 2023 Mar 24. Aging (Albany NY). 2023. PMID: 36988502 Free PMC article. No abstract available.
2,220 results