Occupational Differences in C-Reactive Protein Among Working-Age Adults in South Korea

J Occup Environ Med. 2020 Mar;62(3):194-201. doi: 10.1097/JOM.0000000000001781.

Abstract

Objective: To examine the association between occupational class and high-sensitivity C-reactive protein (hsCRP) in Korean workers.

Methods: We used a nationally representative sample of Koreans (n = 2591) aged 19 to 65 years from the 2015 Korea National Health and Nutrition Examination Survey. The concentration of hsCRP (mg/L) was assessed by a high sensitivity immunoturbidimetric assay. Current occupation was categorized as: white-collar (managers/professionals), pink-collar (clerks/service/sales), blue-collar (craft/equipment/machine-assembling, agricultural/forestry/fishery, and elementary-level labor), or unemployed. Cross-sectional linear regression models adjusted for sociodemographic/work-related/health conditions and behaviors.

Results: Compared with blue-collar workers, white-collar workers showed significantly higher levels of hsCRP (β = 0.16, 95% CI: 0.02, 0.30) after adjusting for all covariates, whereby the pattern was more pronounced among professionals. However, the association was not significant for unemployed and pink-collar workers.

Conclusions: Findings suggest that Korean white-collar workers, particularly professionals, have elevated levels of inflammation.

MeSH terms

  • Adult
  • Aged
  • C-Reactive Protein*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nutrition Surveys
  • Occupational Exposure*
  • Occupations
  • Odds Ratio
  • Republic of Korea
  • Risk Factors
  • Young Adult

Substances

  • C-Reactive Protein