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Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520.
Raymond M, Ruetz S, Thomas DY, Gros P. Raymond M, et al. Mol Cell Biol. 1994 Jan;14(1):277-86. doi: 10.1128/mcb.14.1.277-286.1994. Mol Cell Biol. 1994. PMID: 7505392 Free PMC article.
We have recently reported that expression in yeast cells of P-glycoprotein (P-gp) encoded by the mouse multidrug resistance mdr3 gene (Mdr3) can complement a null ste6 mutation (M. Raymond, P. Gros, M. Whiteway, and D. Y. Thomas, Science 256:232-234, 1992). Here we show th …
We have recently reported that expression in yeast cells of P-glycoprotein (P-gp) encoded by the mouse multidrug resistance mdr3 gene (Mdr3) …