Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors.
Tang CSM, Mononen M, Lam WY, Jin SC, Zhuang X, Garcia-Barcelo MM, Lin Q, Yang Y, Sahara M, Eroglu E, Chien KR, Hong H, Tam PKH, Gruber PJ.
Tang CSM, et al.
JCI Insight. 2022 Jan 25;7(2):e152198. doi: 10.1172/jci.insight.152198.
JCI Insight. 2022.
PMID: 34905512
Free PMC article.
Tetralogy of Fallot (TOF) is the most common cyanotic heart defect, yet the underlying genetic mechanisms remain poorly understood. ...These integrative functional analyses help dissect the pathogenesis of TOF, revealing cellular hotspots in early heart development …
Tetralogy of Fallot (TOF) is the most common cyanotic heart defect, yet the underlying genetic mechanisms remain poorly understood. . …