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Year Number of Results
2008 1
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2015 8
2016 5
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2019 9
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2024 5

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62 results

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Page 1
Targeted complement inhibition and microvasculature in transplants: a therapeutic perspective.
Khan MA, Hsu JL, Assiri AM, Broering DC. Khan MA, et al. Clin Exp Immunol. 2016 Feb;183(2):175-86. doi: 10.1111/cei.12713. Epub 2015 Nov 5. Clin Exp Immunol. 2016. PMID: 26404106 Free PMC article. Review.
This review discusses the mechanism that complement contributes to angiogenic injury, and the development of future therapeutic targets by antagonizing activated complement mediators to preserve microvasculature in rejecting the transplanted organ....
This review discusses the mechanism that complement contributes to angiogenic injury, and the development of future therapeutic targets …
A Review of Multifunction Smart Nanoparticle based Drug Delivery Systems.
Fatima H, Naz MY, Shukrullah S, Aslam H, Ullah S, Assiri MA. Fatima H, et al. Curr Pharm Des. 2022;28(36):2965-2983. doi: 10.2174/1381612828666220422085702. Curr Pharm Des. 2022. PMID: 35466867 Review.
Modern nano-based targeting techniques have been developed as a result of advances in nano vehicle engineering and materials science, which may bring people with cancer a new hope. ...Nanotherapeutics can carry preloaded active medicine towards cancerous cells by preferent …
Modern nano-based targeting techniques have been developed as a result of advances in nano vehicle engineering and materials science, …
An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders.
Alghamdi M, Alasmari D, Assiri A, Mattar E, Aljaddawi AA, Alattas SG, Redwan EM. Alghamdi M, et al. J Immunol Res. 2019 Nov 25;2019:7592851. doi: 10.1155/2019/7592851. eCollection 2019. J Immunol Res. 2019. PMID: 31886309 Free PMC article. Review.
The irreversible citrullination reaction is not limited to a specific protein, cell, or tissue. It can target a wide range of proteins in the cell membrane, cytoplasm, nucleus, and mitochondria. ...
The irreversible citrullination reaction is not limited to a specific protein, cell, or tissue. It can target a wide range of protein …
Therapeutic nexus of T cell immunometabolism in improving transplantation immunotherapy.
Kazmi S, Khan MA, Shamma T, Altuhami A, Assiri AM, Broering DC. Kazmi S, et al. Int Immunopharmacol. 2022 May;106:108621. doi: 10.1016/j.intimp.2022.108621. Epub 2022 Feb 18. Int Immunopharmacol. 2022. PMID: 35189469 Review.
Immunometabolism is a therapeutic strategy to tune immune cells through metabolic reprogramming, which allows immune cells to be differentiated according to their energy requirements. Recent therapeutic strategies targeting immunometabolism suggest that intracellular metab …
Immunometabolism is a therapeutic strategy to tune immune cells through metabolic reprogramming, which allows immune cells to be differentia …
Emerging commercial molecular tests for the diagnosis of bloodstream infection.
Mwaigwisya S, Assiri RA, O'Grady J. Mwaigwisya S, et al. Expert Rev Mol Diagn. 2015 May;15(5):681-92. doi: 10.1586/14737159.2015.1029459. Epub 2015 Apr 12. Expert Rev Mol Diagn. 2015. PMID: 25866124 Review.
While clinicians wait for culture diagnosis, patients are treated empirically, which can result in inappropriate treatment, undesirable side effects and contribute to drug resistance development. Molecular diagnostics assays that target pathogen DNA can identify pathogens …
While clinicians wait for culture diagnosis, patients are treated empirically, which can result in inappropriate treatment, undesirable side …
Technological Advancement in ω-3 Fatty Acids: Their Therapeutic Functions and Novel Delivery Strategies.
Victor F, Rehman K, Akash MSH, Rasheed S, Imran M, Assiri MA. Victor F, et al. Curr Pharm Des. 2023;29(12):839-903. doi: 10.2174/1381612829666230330144614. Curr Pharm Des. 2023. PMID: 37005402 Review.
Although numerous supplementation strategies have been developed to enhance the bioavailability, targeted drug delivery, and therapeutic potential, the rate of compliance is low due to difficulty in swallowing and unpleasant aftertaste. ...
Although numerous supplementation strategies have been developed to enhance the bioavailability, targeted drug delivery, and therapeu …
Metal-organic frameworks (MOFs) based nanofiber architectures for the removal of heavy metal ions.
Adil HI, Thalji MR, Yasin SA, Saeed IA, Assiri MA, Chong KF, Ali GAM. Adil HI, et al. RSC Adv. 2022 Jan 7;12(3):1433-1450. doi: 10.1039/d1ra07034g. eCollection 2022 Jan 5. RSC Adv. 2022. PMID: 35425211 Free PMC article. Review.
In addition, the substantial adsorption capacities are mainly due to interactions between the target ions and functional binding groups on the MOFs-nanofiber composites and the highly ordered porous structure....
In addition, the substantial adsorption capacities are mainly due to interactions between the target ions and functional binding grou …
β-catenin attenuation leads to up-regulation of activating NKG2D ligands and tumor regression in BrafV600E-driven thyroid cancer cells.
Zou M, Al-Yahya S, Al-Alwan M, BinEssa HA, Khabar KSA, Almohanna F, Assiri AM, Altaweel A, Qattan A, Meyer BF, Alzahrani AS, Shi Y. Zou M, et al. Front Immunol. 2023 Jul 6;14:1171816. doi: 10.3389/fimmu.2023.1171816. eCollection 2023. Front Immunol. 2023. PMID: 37483610 Free PMC article.
CONCLUSIONS: Our results indicate that active beta-catenin signaling inhibits NK cell-mediated immune responses against thyroid cancer cells. Targeting the beta-catenin signaling pathway may have significant therapeutic benefits for BRAF-mutant thyroid cancer by not only i …
CONCLUSIONS: Our results indicate that active beta-catenin signaling inhibits NK cell-mediated immune responses against thyroid cancer cells …
Non-coding RNAs as key players in the neurodegenerative diseases: Multi-platform strategies and approaches for exploring the Genome's dark matter.
Almohaimeed HM, Assiri R, Althubaiti EH, Aggad WS, Shaheen S, Shaheen MY, Batarfi MA, Alharbi NA, Alshehri AM, Alkhudhairy BSM. Almohaimeed HM, et al. J Chem Neuroanat. 2023 Apr;129:102236. doi: 10.1016/j.jchemneu.2023.102236. Epub 2023 Jan 25. J Chem Neuroanat. 2023. PMID: 36709005 Review.
Despite these advances, the understanding of their potential as therapeutic targets and biomarkers underpinning detailed mechanisms is still unknown. ...
Despite these advances, the understanding of their potential as therapeutic targets and biomarkers underpinning detailed mechanisms i …
62 results