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Design and synthesis of 3,3-piperidine hydroxamate analogs as selective TACE inhibitors.
Bioorg Med Chem Lett. 2007 Aug 1;17(15):4333-7. doi: 10.1016/j.bmcl.2007.05.022. Epub 2007 May 16.
Bioorg Med Chem Lett. 2007.
PMID: 17531482
Characterization of (2R, 3S)-2-([[4-(2-butynyloxy)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-alpha converting enzyme.
Zhang Y, Hegen M, Xu J, Keith JC Jr, Jin G, Du X, Cummons T, Sheppard BJ, Sun L, Zhu Y, Rao VR, Wang Q, Xu W, Cowling R, Nickerson-Nutter CL, Gibbons J, Skotnicki J, Lin LL, Levin J.
Zhang Y, et al.
Int Immunopharmacol. 2004 Dec 20;4(14):1845-57. doi: 10.1016/j.intimp.2004.08.003.
Int Immunopharmacol. 2004.
PMID: 15531300
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Design and synthesis of butynyloxyphenyl beta-sulfone piperidine hydroxamates as TACE inhibitors.
Park K, Aplasca A, Du MT, Sun L, Zhu Y, Zhang Y, Levin JI.
Park K, et al.
Bioorg Med Chem Lett. 2006 Aug 1;16(15):3927-31. doi: 10.1016/j.bmcl.2006.05.026. Epub 2006 May 24.
Bioorg Med Chem Lett. 2006.
PMID: 16723229
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