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An EF-hands protein, centrin-1, is an EGTA-sensitive SUMO-interacting protein in mouse testis.
Tanaka N, Goto M, Kawasaki A, Sasano T, Eto K, Nishi R, Sugasawa K, Abe S, Saitoh H. Tanaka N, et al. Cell Biochem Funct. 2010 Oct;28(7):604-12. doi: 10.1002/cbf.1698. Cell Biochem Funct. 2010. PMID: 20941751
In bead halo assays, the interaction between centrin-1 and SUMO-2/3 was reduced in the presence of EGTA and facilitated by the addition of CaCl2. immunostaining of seminiferous tubules in 35-day-old mouse testes revealed that cells in the layer containing spermatogonia sho …
In bead halo assays, the interaction between centrin-1 and SUMO-2/3 was reduced in the presence of EGTA and facilitated by the additi …
PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.
Matsuura T, Shimono Y, Kawai K, Murakami H, Urano T, Niwa Y, Goto H, Takahashi M. Matsuura T, et al. Exp Cell Res. 2005 Aug 1;308(1):65-77. doi: 10.1016/j.yexcr.2005.04.022. Exp Cell Res. 2005. PMID: 15907835
In addition, co-expression of PIAS proteins or SUMO-1 strengthened the transcriptional repressive activity of RFP. Finally, our immunohistochemical results show that RFP, SUMO-1 and PIASy localize in a characteristic nuclear structure juxtaposed with the inner nucle …
In addition, co-expression of PIAS proteins or SUMO-1 strengthened the transcriptional repressive activity of RFP. Finally, our immun …
Enhanced SUMOylation in polyglutamine diseases.
Ueda H, Goto J, Hashida H, Lin X, Oyanagi K, Kawano H, Zoghbi HY, Kanazawa I, Okazawa H. Ueda H, et al. Biochem Biophys Res Commun. 2002 Apr 26;293(1):307-13. doi: 10.1016/S0006-291X(02)00211-5. Biochem Biophys Res Commun. 2002. PMID: 12054600
We examined patients of DRPLA, SCA1, MJD, and Huntington's disease and found that neurons in affected regions of the brain react strongly to SUMO-1, a family member of SUMOs. Western blot with a transgenic mouse expressing mutant ataxin-1 showed the increase of SUMOylated …
We examined patients of DRPLA, SCA1, MJD, and Huntington's disease and found that neurons in affected regions of the brain react strongly to …
Impact of the approval of intravenous recombinant tissue plasminogen activator therapy on the processes of acute stroke management in Japan: the Stroke Unit Multicenter Observational (SUMO) Study.
Sato S, Uehara T, Toyoda K, Yasui N, Hata T, Ueda T, Okada Y, Toyota A, Hasegawa Y, Naritomi H, Minematsu K; Stroke Unit Multicenter Observational (SUMO) Study Group. Sato S, et al. Stroke. 2009 Jan;40(1):30-4. doi: 10.1161/STROKEAHA.108.524942. Epub 2008 Oct 23. Stroke. 2009. PMID: 18948604
Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals.
Leitao B, Jones MC, Fusi L, Higham J, Lee Y, Takano M, Goto T, Christian M, Lam EW, Brosens JJ. Leitao B, et al. FASEB J. 2010 May;24(5):1541-51. doi: 10.1096/fj.09-149153. Epub 2009 Dec 21. FASEB J. 2010. PMID: 20026682 Free PMC article.
Overexpression of MKP1 dampens JNK signaling, prevents hypersumoylation, and maintains PR activity in undifferentiated HESCs exposed to ROS. Thus, JNK silencing uncouples ROS signaling from the SUMO conjugation pathway and maintains progesterone responses and cellular home …
Overexpression of MKP1 dampens JNK signaling, prevents hypersumoylation, and maintains PR activity in undifferentiated HESCs exposed to ROS. …