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Page 1
Dabigatran versus warfarin in patients with atrial fibrillation.
Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, Pogue J, Reilly PA, Themeles E, Varrone J, Wang S, Alings M, Xavier D, Zhu J, Diaz R, Lewis BS, Darius H, Diener HC, Joyner CD, Wallentin L; RE-LY Steering Committee and Investigators. Connolly SJ, et al. N Engl J Med. 2009 Sep 17;361(12):1139-51. doi: 10.1056/NEJMoa0905561. Epub 2009 Aug 30. N Engl J Med. 2009. PMID: 19717844 Free article. Clinical Trial.
High-stress distribution in the lateral region of the subtalar joint in the patient with chronic lateral ankle instability.
Nakasa T, Ikuta Y, Sumii J, Nekomoto A, Adachi N. Nakasa T, et al. Arch Orthop Trauma Surg. 2022 Jul;142(7):1579-1587. doi: 10.1007/s00402-021-04078-6. Epub 2021 Jul 20. Arch Orthop Trauma Surg. 2022. PMID: 34286364
Color map was created in the ankle and subtalar joint according to the HU values using three-dimensional CT to identify the region with high HU values, and HU values in those regions were measured using two-dimensional CT and compared between control and CLAI …
Color map was created in the ankle and subtalar joint according to the HU values using three-dimensional CT to identify the region wi …
Distributional patterns of subchondral bone density and histopathological features of the first tarsometatarsal joint in hallux valgus feet.
Ikuta Y, Nakasa T, Sumii J, Nekomoto A, Adachi N. Ikuta Y, et al. BMC Musculoskelet Disord. 2022 Jun 14;23(1):569. doi: 10.1186/s12891-022-05523-2. BMC Musculoskelet Disord. 2022. PMID: 35701770 Free PMC article.
The HU ratios were calculated, which were defined as the HU value of each subdivision of the subarticular spongiosa of the first TMT joint [dorsomedial (DM), dorsolateral (DL), plantomedial (PM), and plantolateral (PL)] divided by the HU values of the entire …
The HU ratios were calculated, which were defined as the HU value of each subdivision of the subarticular spongiosa of the fir …
Quantitative Analysis of Deltoid Ligament Degradation in Patients With Chronic Ankle Instability Using Computed Tomographic Images.
Ikuta Y, Nakasa T, Sumii J, Nekomoto A, Adachi N. Ikuta Y, et al. Foot Ankle Int. 2021 Jul;42(7):952-958. doi: 10.1177/1071100721997070. Epub 2021 Mar 11. Foot Ankle Int. 2021. PMID: 33703931

RESULTS: A strong negative correlation was identified between age and HU values for all patients (Spearman rho = -0.63; P < .001). The mean HU values of the dPTL for participants aged <60 years were 81.0 HU for the control group (21 ankles) and 69.5

…

RESULTS: A strong negative correlation was identified between age and HU values for all patients (Spearman rho = -0.63; P < .001).

…
Bone Mineralization Changes in the Subchondral Bone of the Medial Gutter in Chronic Lateral Ankle Instability.
Nakasa T, Ikuta Y, Ota Y, Kanemitsu M, Sumii J, Nekomoto A, Adachi N. Nakasa T, et al. Foot Ankle Int. 2020 Nov;41(11):1419-1426. doi: 10.1177/1071100720938049. Epub 2020 Jul 19. Foot Ankle Int. 2020. PMID: 32686491
RESULTS: The mean HU ratio in the CAI group was significantly higher than that in the control. ...But there was no significant difference in the HU ratios with or without OA change in the medial gutter. A good-quality ATFL remnant showed a low HU ratio compar …
RESULTS: The mean HU ratio in the CAI group was significantly higher than that in the control. ...But there was no significant differ …
Histopathological and Radiographic Features of Osteolysis After Fixation of Osteochondral Fragments Using Poly-L-Lactic Acid Pins for Osteochondral Lesions of the Talus.
Ikuta Y, Nakasa T, Sumii J, Nekomoto A, Adachi N. Ikuta Y, et al. Am J Sports Med. 2021 May;49(6):1589-1595. doi: 10.1177/03635465211001758. Epub 2021 Mar 29. Am J Sports Med. 2021. PMID: 33780270
PURPOSE: To elucidate the association between osteolysis surrounding the PLLA pins, histopathological findings in subchondral bone, and preoperative Hounsfield unit (HU) values at the pin fixation site. STUDY DESIGN: Case Series; Level of evidence, 4. ...The histopathologi …
PURPOSE: To elucidate the association between osteolysis surrounding the PLLA pins, histopathological findings in subchondral bone, and preo …
Hounsfield Unit values on the subchondral bone are related to clinical outcomes in bone marrow stimulation for osteochondral lesions of the talus.
Kawabata S, Nakasa T, Ikuta Y, Sumii J, Nekomoto A, Adachi N. Kawabata S, et al. J Orthop Sci. 2023 Jun 22:S0949-2658(23)00145-8. doi: 10.1016/j.jos.2023.06.002. Online ahead of print. J Orthop Sci. 2023. PMID: 37355459
METHODS: Sixty-nine ankles in 61 patients with OLT were included. Hounsfield unit (HU) on the bed of OLTs was measured on CT images and the pattern of osteosclerosis or absorption in the bed was analyzed. ...CONCLUSION: Osteosclerotic changes in the anterior part of the be …
METHODS: Sixty-nine ankles in 61 patients with OLT were included. Hounsfield unit (HU) on the bed of OLTs was measured on CT images a …
Relationship between pain and intra-articular pathology in patients with chronic lateral ankle instability.
Nakasa T, Ikuta Y, Sumii J, Nekomoto A, Kawabata S, Adachi N. Nakasa T, et al. Arch Orthop Trauma Surg. 2024 Feb;144(2):815-822. doi: 10.1007/s00402-023-05123-2. Epub 2023 Nov 20. Arch Orthop Trauma Surg. 2024. PMID: 37982838
The arthroscopic synovitis score and HU ratios in patients with high pain scores were significantly higher than those in patients with low pain scores. ...Multiple regression analysis revealed that a high synovitis score and HU ratio of the talus were significantly …
The arthroscopic synovitis score and HU ratios in patients with high pain scores were significantly higher than those in patients wit …
High incidence of osteoarthritic changes in patients with osteochondral lesions of the talus without chronic lateral ankle instability.
Kawabata S, Nakasa T, Ikuta Y, Sumii J, Nekomoto A, Adachi N. Kawabata S, et al. J Orthop Sci. 2024 Jan;29(1):249-255. doi: 10.1016/j.jos.2022.12.007. Epub 2022 Dec 23. J Orthop Sci. 2024. PMID: 36567196
On computed tomography images, the area of OLTs was measured. Besides, Hounsfield Units (HU) of the talus in patients with and without OLTs were measured and compared. ...The OA score in patients aged over 18 years was significantly higher than that in patients aged less t …
On computed tomography images, the area of OLTs was measured. Besides, Hounsfield Units (HU) of the talus in patients with and withou …