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1967 1
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Population Dynamics of Epithelial-Mesenchymal Heterogeneity in Cancer Cells.
Jain P, Bhatia S, Thompson EW, Jolly MK. Jain P, et al. Biomolecules. 2022 Feb 23;12(3):348. doi: 10.3390/biom12030348. Biomolecules. 2022. PMID: 35327538 Free PMC article.
Our framework proposes that fluctuations or noise in content duplication and partitioning of SNAIL-an EMT-inducing transcription factor-during cell division can explain spontaneous phenotypic switching and consequent dynamic heterogeneity in PMC42-LA cells observed experim …
Our framework proposes that fluctuations or noise in content duplication and partitioning of SNAIL-an EMT-inducing transcription fact …
Constrained de novo sequencing of conotoxins.
Bhatia S, Kil YJ, Ueberheide B, Chait BT, Tayo L, Cruz L, Lu B, Yates JR 3rd, Bern M. Bhatia S, et al. J Proteome Res. 2012 Aug 3;11(8):4191-200. doi: 10.1021/pr300312h. Epub 2012 Jul 2. J Proteome Res. 2012. PMID: 22709442 Free PMC article.
We demonstrate our algorithm in a study of cysteine-rich toxins from two cone snail species (Conus textile and Conus stercusmuscarum) and report 13 de novo and about 60 total toxins....
We demonstrate our algorithm in a study of cysteine-rich toxins from two cone snail species (Conus textile and Conus stercusmuscarum) …
The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme.
Bhatia S, Bukkapatnam S, Van Court B, Phan A, Oweida A, Gadwa J, Mueller AC, Piper M, Darragh L, Nguyen D, Gilani A, Knitz M, Bickett T, Green A, Venkataraman S, Vibhakar R, Cittelly D, Karam SD. Bhatia S, et al. Mol Carcinog. 2020 Sep;59(9):1064-1075. doi: 10.1002/mc.23237. Epub 2020 Jun 22. Mol Carcinog. 2020. PMID: 32567728 Free PMC article.
EphB4 stimulation following ephrinB2 Fc treatment in ephrinB2 knockdown tumors was shown to impart strong anti-proliferative and anti-invasive effects, which correlated with decrease in PCNA, p-ERK, vimentin, Snail, Fak, and increase in the E-cadherin levels. Overall, our …
EphB4 stimulation following ephrinB2 Fc treatment in ephrinB2 knockdown tumors was shown to impart strong anti-proliferative and anti-invasi …