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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 2
2005 2
2007 4
2008 1
2009 1
2010 1
2011 3
2012 5
2013 2
2014 1
2015 1
2016 2
2018 3
2019 2
2020 1
2021 1
2022 3
2024 0

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33 results

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Page 1
Optimization of Lipid Nanoparticles for saRNA Expression and Cellular Activation Using a Design-of-Experiment Approach.
Ly HH, Daniel S, Soriano SKV, Kis Z, Blakney AK. Ly HH, et al. Mol Pharm. 2022 Jun 6;19(6):1892-1905. doi: 10.1021/acs.molpharmaceut.2c00032. Epub 2022 May 23. Mol Pharm. 2022. PMID: 35604765 Free PMC article.
Lipid nanoparticles (LNPs) are the leading technology for RNA delivery, given the success of the Pfizer/BioNTech and Moderna COVID-19 mRNA (mRNA) vaccines, and small interfering RNA (siRNA) therapies (patisiran). However, optimization of LNP pro …
Lipid nanoparticles (LNPs) are the leading technology for RNA delivery, given the success of the Pfizer/BioNTech and Moderna COVID-19 …
siRNA-optimized Modifications for Enhanced In Vivo Activity.
Kenski DM, Butora G, Willingham AT, Cooper AJ, Fu W, Qi N, Soriano F, Davies IW, Flanagan WM. Kenski DM, et al. Mol Ther Nucleic Acids. 2012 Jan 24;1(1):e5. doi: 10.1038/mtna.2011.4. Mol Ther Nucleic Acids. 2012. PMID: 23344622 Free PMC article.
Current modifications used in small interfering RNAs (siRNAs), such as 2'-methoxy (2'-OMe) and 2'-fluoro (2'-F), improve stability, specificity or immunogenic properties but do not improve potency. ...Increased in vivo activity was observed when the modificat …
Current modifications used in small interfering RNAs (siRNAs), such as 2'-methoxy (2'-OMe) and 2'-fluoro (2'-F), improv …
Engineering pH-Sensitive Stable Nanovesicles for Delivery of MicroRNA Therapeutics.
Boloix A, Feiner-Gracia N, Köber M, Repetto J, Pascarella R, Soriano A, Masanas M, Segovia N, Vargas-Nadal G, Merlo-Mas J, Danino D, Abutbul-Ionita I, Foradada L, Roma J, Córdoba A, Sala S, de Toledo JS, Gallego S, Veciana J, Albertazzi L, Segura MF, Ventosa N. Boloix A, et al. Small. 2022 Jan;18(3):e2101959. doi: 10.1002/smll.202101959. Epub 2021 Nov 16. Small. 2022. PMID: 34786859 Free article.
MicroRNAs (miRNAs) are small non-coding endogenous RNAs, which are attracting a growing interest as therapeutic molecules due to their central role in major diseases. ...Herein, the engineering of non-liposomal lipid nanovesicles, named quatsomes (QS), for the delivery of …
MicroRNAs (miRNAs) are small non-coding endogenous RNAs, which are attracting a growing interest as therapeutic molecules due to thei …
Adenovirus 5 E1A-Mediated Suppression of p53 via FUBP1.
Frost JR, Mendez M, Soriano AM, Crisostomo L, Olanubi O, Radko S, Pelka P. Frost JR, et al. J Virol. 2018 Jun 29;92(14):e00439-18. doi: 10.1128/JVI.00439-18. Print 2018 Jul 15. J Virol. 2018. PMID: 29743362 Free PMC article.
Recent studies have identified FUBP1 as a regulator of transcription, translation, and splicing via its DNA and RNA binding activities. Here we report the identification of FUBP1 as a novel binding partner of E1A. FUBP1 binds directly to E1A via the N terminus (residues 1 …
Recent studies have identified FUBP1 as a regulator of transcription, translation, and splicing via its DNA and RNA binding activitie …
MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness.
Planells-Ferrer L, Urresti J, Soriano A, Reix S, Murphy DM, Ferreres JC, Borràs F, Gallego S, Stallings RL, Moubarak RS, Segura MF, Comella JX. Planells-Ferrer L, et al. Cell Death Dis. 2014 Sep 4;5(9):e1401. doi: 10.1038/cddis.2014.356. Cell Death Dis. 2014. PMID: 25188511 Free PMC article.
Cortistatin regulates glucose-induced electrical activity and insulin secretion in mouse pancreatic beta-cells.
Soriano S, Castellano-Muñoz M, Rafacho A, Alonso-Magdalena P, Marroquí L, Ruiz-Pino A, Bru-Tarí E, Merino B, Irles E, Bello-Pérez M, Iborra P, Villar-Pazos S, Vettorazzi JF, Montanya E, Luque RM, Nadal Á, Quesada I. Soriano S, et al. Mol Cell Endocrinol. 2019 Jan 5;479:123-132. doi: 10.1016/j.mce.2018.09.009. Epub 2018 Sep 24. Mol Cell Endocrinol. 2019. PMID: 30261212
Cortistatin did not modify ATP-dependent K(+) (K(ATP)) channel activity. In contrast, cortistatin increased the activity of a small conductance channel with characteristics of G protein-coupled inwardly rectifying K(+) (GIRK) channels. The cortistatin effects on membrane p …
Cortistatin did not modify ATP-dependent K(+) (K(ATP)) channel activity. In contrast, cortistatin increased the activity of a small c …
Mobilization of iron from ferritin: new steps and details.
La A, Nguyen T, Tran K, Sauble E, Tu D, Gonzalez A, Kidane TZ, Soriano C, Morgan J, Doan M, Tran K, Wang CY, Knutson MD, Linder MC. La A, et al. Metallomics. 2018 Jan 24;10(1):154-168. doi: 10.1039/c7mt00284j. Metallomics. 2018. PMID: 29260183
Ferrihydrite crystals isolated from purified rat liver/spleen ferritin were solubilized at pH 5 and 7 by GSH, ascorbate, citrate and lysosomal fluids obtained from livers and J774a.1 macrophages. The inhibition of DMT1/Nramp2 and siRNA knockdown of Nramp1 each reduced the …
Ferrihydrite crystals isolated from purified rat liver/spleen ferritin were solubilized at pH 5 and 7 by GSH, ascorbate, citrate and lysosom …
The armadillo-repeat containing X-linked protein 3, ARMCX3, is a negative regulator of the browning of adipose tissue associated with obesity.
Gavaldà-Navarro A, Mirra S, Manso Y, Sánchez-Infantes D, Giralt M, Soriano E, Villarroya F. Gavaldà-Navarro A, et al. Int J Obes (Lond). 2022 Sep;46(9):1652-1661. doi: 10.1038/s41366-022-01169-1. Epub 2022 Jun 15. Int J Obes (Lond). 2022. PMID: 35705702
Experimentally-induced increases in Armcx3 caused down-regulation of thermogenesis-related genes and reduced mitochondrial oxidative activity of adipocytes in culture, whereas siRNA-mediated Armcx3 knocking-down enhanced expression of thermogenesis-related genes. ...
Experimentally-induced increases in Armcx3 caused down-regulation of thermogenesis-related genes and reduced mitochondrial oxidative activit …
33 results