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Did you mean six key im (3,569 results)?
Cyclophilin A accelerates SiO(2)-induced macrophage foaming.
Liu H, He H, Tian Y, Cui J, Wang S, Wang H. Liu H, et al. Cell Signal. 2023 Mar;103:110562. doi: 10.1016/j.cellsig.2022.110562. Epub 2022 Dec 16. Cell Signal. 2023. PMID: 36535629 Free article.
Silicosis is a common occupational disease characterized by lung inflammation, fibrosis and pulmonary dysfunction caused by long-term inhalation of free SiO(2). Cell foaming and the change of CyPA have been observed in SiO(2)-induced macrophages, but the specific me …
Silicosis is a common occupational disease characterized by lung inflammation, fibrosis and pulmonary dysfunction caused by long-term inhala …
Optimized Design Method for Pt/SiO(2)-Al(2)O(3) with High NH(3)-SCO Activity and Thermal Stability.
Sun M, Zhou S, Wang S, Song C. Sun M, et al. ACS Omega. 2022 Jan 21;7(4):3177-3184. doi: 10.1021/acsomega.1c03780. eCollection 2022 Feb 1. ACS Omega. 2022. PMID: 35128230 Free PMC article.
Pt/SiO(2)-Al(2)O(3) catalysts were prepared by the traditional impregnation method (IM) and the strong electrostatic adsorption (SEA) process. ...After hydrothermal aging, Pt species did not show obvious agglomeration (the average particle size was 3.2 nm). Above al …
Pt/SiO(2)-Al(2)O(3) catalysts were prepared by the traditional impregnation method (IM) and the strong electrostatic adsorptio …
Divarasib plus cetuximab in KRAS G12C-positive colorectal cancer: a phase 1b trial.
Desai J, Alonso G, Kim SH, Cervantes A, Karasic T, Medina L, Shacham-Shmueli E, Cosman R, Falcon A, Gort E, Guren T, Massarelli E, Miller WH Jr, Paz-Ares L, Prenen H, Amatu A, Cremolini C, Kim TW, Moreno V, Ou SI, Passardi A, Sacher A, Santoro A, Stec R, Ulahannan S, Arbour K, Lorusso P, Luo J, Patel MR, Choi Y, Shi Z, Mandlekar S, Lin MT, Royer-Joo S, Chang J, Jun T, Dharia NV, Schutzman JL; GO42144 Investigator and Study Group; Han SW. Desai J, et al. Nat Med. 2024 Jan;30(1):271-278. doi: 10.1038/s41591-023-02696-8. Epub 2023 Dec 5. Nat Med. 2024. PMID: 38052910 Free PMC article. Clinical Trial.
Epidermal growth factor receptor has been recognized as a major upstream activator of RAS-MAPK signaling, a proposed key mechanism of resistance to KRAS G12C inhibition in CRC. Here, we report on divarasib plus cetuximab (epidermal growth factor receptor inhibitor) in pati …
Epidermal growth factor receptor has been recognized as a major upstream activator of RAS-MAPK signaling, a proposed key mechanism of …
Antigen-Conjugated Silica Solid Sphere as Nanovaccine for Cancer Immunotherapy.
Dong Y, Gao J, Pei M, Wang X, Zhang C, Du Y, Jiang Y. Dong Y, et al. Int J Nanomedicine. 2020 Apr 22;15:2685-2697. doi: 10.2147/IJN.S242463. eCollection 2020. Int J Nanomedicine. 2020. PMID: 32368049 Free PMC article.
OVA was covalently conjugated on the surface of activated SiO(2) to obtain nanovaccine (OVA@SiO(2)). Dynamic light scattering, scanning electron microscope, and transmission electron microscope were conducted to identify the size distribution, zeta potential and mor …
OVA was covalently conjugated on the surface of activated SiO(2) to obtain nanovaccine (OVA@SiO(2)). Dynamic light scattering, …
P-Doped SiO(x) /Si/SiO(x) Sandwich Anode for Li-Ion Batteries to Achieve High Initial Coulombic Efficiency and Low Capacity Decay.
Im J, Kwon JD, Kim DH, Yoon S, Cho KY. Im J, et al. Small Methods. 2022 Mar;6(3):e2101052. doi: 10.1002/smtd.202101052. Epub 2021 Nov 28. Small Methods. 2022. PMID: 35312227
However, it suffers from colossal volume change and continuous formation of unstable solid electrolyte interphases during lithiation/delithiation processes, which eventually result in low initial Coulombic efficiency (ICE) and severe capacity decay. To circumvent these challenges …
However, it suffers from colossal volume change and continuous formation of unstable solid electrolyte interphases during lithiation/delithi …
Evaluation of Chitosan Derivatives Modified Mesoporous Silica Nanoparticles as Delivery Carrier.
Li Q, Wang W, Hu G, Cui X, Sun D, Jin Z, Zhao K. Li Q, et al. Molecules. 2021 Apr 24;26(9):2490. doi: 10.3390/molecules26092490. Molecules. 2021. PMID: 33923304 Free PMC article.
Chitosan derivatives N-2-Hydroxypropyl trimethyl ammonium chloride (N-2-HACC) and carboxymethyl chitosan (CMCS) with good water solubility were synthesized by our laboratory. In this study, we synthesized mesoporous SiO(2) nanoparticles by the emulsion, and then the mesopo …
Chitosan derivatives N-2-Hydroxypropyl trimethyl ammonium chloride (N-2-HACC) and carboxymethyl chitosan (CMCS) with good water solubility w …
SiO(2) prompts host defense against Acinetobacter baumannii infection by mTORC1 activation.
Guo X, Wang C, Xu T, Yang L, Liu C, Qi X. Guo X, et al. Sci China Life Sci. 2021 Jun;64(6):982-990. doi: 10.1007/s11427-020-1781-8. Epub 2020 Sep 1. Sci China Life Sci. 2021. PMID: 32880864
We performed Acinetobacter baumannii infection in mice with chronic pulmonary inflammation after intranasal administration of SiO(2) and found SiO(2) treatment increased host defense against A. baumannii infection. Innate immune responses initiated by NF-kappaB, typ …
We performed Acinetobacter baumannii infection in mice with chronic pulmonary inflammation after intranasal administration of SiO(2) …
Molecular genetic analysis of the calcineurin signaling pathways.
Sugiura R, Sio SO, Shuntoh H, Kuno T. Sugiura R, et al. Cell Mol Life Sci. 2001 Feb;58(2):278-88. doi: 10.1007/PL00000855. Cell Mol Life Sci. 2001. PMID: 11289309 Review.
Notably, specific transcription factors have been shown to play a key role in regulating these functions, and their calcineurin-mediated dephosphorylation and nuclear translocation appear to be a central event in the signal transduction pathways. ...
Notably, specific transcription factors have been shown to play a key role in regulating these functions, and their calcineurin-media …
Nanoparticle/Nanocarrier Formulation as an Antigen: The Immunogenicity and Antigenicity of Itself.
Li L, Yan X, Xia M, Shen B, Cao Y, Wu X, Sun J, Zhang Y, Zhang M. Li L, et al. Mol Pharm. 2022 Jan 3;19(1):148-159. doi: 10.1021/acs.molpharmaceut.1c00704. Epub 2021 Dec 10. Mol Pharm. 2022. PMID: 34886673
Moreover, several promising nanoparticle drug carrier immunogens (e.g., SiO(2), oleylamine graft polysuccinimide (PSI(OAm)), oleylamine and N-(3-aminopropyl)imidazole cograft polysuccinimide (PSI(OAm-NAPI)), Fe(3)O(4)@O-dextran, etc.) showed excellent immunogenicity. ...
Moreover, several promising nanoparticle drug carrier immunogens (e.g., SiO(2), oleylamine graft polysuccinimide (PSI(OAm)), oleylami …
Macrophage-derived MCPIP1 mediates silica-induced pulmonary fibrosis via autophagy.
Liu H, Fang S, Wang W, Cheng Y, Zhang Y, Liao H, Yao H, Chao J. Liu H, et al. Part Fibre Toxicol. 2016 Oct 25;13(1):55. doi: 10.1186/s12989-016-0167-z. Part Fibre Toxicol. 2016. PMID: 27782836 Free PMC article.
To elucidate the role of MCPIP1-induced autophagy in SiO(2)-induced fibrosis, both the upstream molecular mechanisms and the functional effects of SiO(2) on cell apoptosis, proliferation and migration were investigated. ...CONCLUSIONS: Our results elucidated a link …
To elucidate the role of MCPIP1-induced autophagy in SiO(2)-induced fibrosis, both the upstream molecular mechanisms and the function …
60 results