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Umbelliferone alleviates hepatic ischemia/reperfusion-induced oxidative stress injury via targeting Keap-1/Nrf-2/ARE and TLR4/NF-κB-p65 signaling pathway.
Hassanein EHM, Khader HF, Elmansy RA, Seleem HS, Elfiky M, Mohammedsaleh ZM, Ali FEM, Abd-Elhamid TH. Hassanein EHM, et al. Environ Sci Pollut Res Int. 2021 Dec;28(47):67863-67879. doi: 10.1007/s11356-021-15184-8. Epub 2021 Jul 15. Environ Sci Pollut Res Int. 2021. PMID: 34268687
Experimentally, forty Wistar albino rats were randomly divided into 4 groups: Sham control group (received 1% carboxymethyl cellulose as a vehicle), UMB group (30 mg/kg/day, P.O.), IR group (subjected to complete hepatic IR injury), and IR + UMB group. ...
Experimentally, forty Wistar albino rats were randomly divided into 4 groups: Sham control group (received 1% carboxymethyl cellulose …
Irisin improves adiposity and exercise tolerance in a rat model of postmenopausal obesity through enhancing adipo-myocyte thermogenesis.
Gheit REAE, Younis RL, El-Saka MH, Emam MN, Soliman NA, El-Sayed RM, Hafez YM, AbuoHashish NA, Radwan DA, Khaled HE, Kamel S, Zaitone SA, Badawi GA. Gheit REAE, et al. J Physiol Biochem. 2022 Nov;78(4):897-913. doi: 10.1007/s13105-022-00915-3. Epub 2022 Aug 23. J Physiol Biochem. 2022. PMID: 35996069 Free PMC article.
The HFD-fed animals were equally divided into OVX/HFD, or irisin-treated OVX/HFD groups. Sham rats, maintained on ND, were selected as the control group. ...
The HFD-fed animals were equally divided into OVX/HFD, or irisin-treated OVX/HFD groups. Sham rats, maintained on ND, were selected a …
The Effect of Cerebrolysin in an Animal Model of Forebrain Ischemic-Reperfusion Injury: New Insights into the Activation of the Keap1/Nrf2/Antioxidant Signaling Pathway.
Marghani BH, Rezk S, Ateya AI, Alotaibi BS, Othman BH, Sayed SM, Alshehri MA, Shukry M, Mansour MM. Marghani BH, et al. Int J Mol Sci. 2023 Jul 28;24(15):12080. doi: 10.3390/ijms241512080. Int J Mol Sci. 2023. PMID: 37569457 Free PMC article.
Five equal groups of six BLC57 mice were created: Group 1: control group (no surgery was performed); Group 2: sham surgery (surgery was performed without IR); Group 3: tDCAL/IR (surgery with IR via permanently ligating the left CA and temporarily closing the right CA for 3 …
Five equal groups of six BLC57 mice were created: Group 1: control group (no surgery was performed); Group 2: sham surgery (surgery w …
Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway.
Ebrahim N, Dessouky AA, Mostafa O, Hassouna A, Yousef MM, Seleem Y, El Gebaly EAEAM, Allam MM, Farid AS, Saffaf BA, Sabry D, Nawar A, Shoulah AA, Khalil AH, Abdalla SF, El-Sherbiny M, Elsherbiny NM, Salim RF. Ebrahim N, et al. Stem Cell Res Ther. 2021 Jul 13;12(1):392. doi: 10.1186/s13287-021-02454-y. Stem Cell Res Ther. 2021. PMID: 34256844 Free PMC article.
METHODS: Albino rats were allocated into 6 groups [control (unwounded), sham (wounded but non-diabetic), diabetic, PRP-treated, ADSC-treated, and PRP+ADSCs-treated groups]. ...
METHODS: Albino rats were allocated into 6 groups [control (unwounded), sham (wounded but non-diabetic), diabetic, PRP-treated, ADSC- …
A Peculiar Binding Characterization of DNA (RNA) Nucleobases at MoOS-Based Janus Biosensor: Dissimilar Facets Role on Selectivity and Sensitivity.
Laref S, Wang B, Inal S, Al-Ghamdi S, Gao X, Gojobori T. Laref S, et al. Biosensors (Basel). 2022 Jun 23;12(7):442. doi: 10.3390/bios12070442. Biosensors (Basel). 2022. PMID: 35884245 Free PMC article.
It has been observed that the introduction of DNA/RNA nucleobases molecules alters the electronic properties of both oxygen and sulfur atomic layers of the Janus MoOS complex systems as determined by plotting the 3D Kohn-Sham frontier orbitals. A good correlation has been …
It has been observed that the introduction of DNA/RNA nucleobases molecules alters the electronic properties of both oxygen and sulfur atomi …
Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats.
Zulfiqar Z, Shah FA, Shafique S, Alattar A, Ali T, Alvi AM, Rashid S, Li S. Zulfiqar Z, et al. J Inflamm Res. 2020 Dec 24;13:1185-1205. doi: 10.2147/JIR.S284471. eCollection 2020. J Inflamm Res. 2020. PMID: 33384558 Free PMC article. Retracted.
After MCAO surgery, severe neurological deficits were detected in the MCAO group compared with the sham controls, which were significantly reversed by dabigatran, estazolam, and pitavastatin treatment. ...
After MCAO surgery, severe neurological deficits were detected in the MCAO group compared with the sham controls, which were signific …