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High yield of surveillance in patients diagnosed with constitutional mismatch repair deficiency.
J Med Genet. 2023 Jul;60(7):679-684. doi: 10.1136/jmg-2022-108829. Epub 2022 Nov 21.
J Med Genet. 2023.
PMID: 36411031
In addition, many adenomas were detected in the duodenum, and colorectum and subsequently removed. Seven patients developed a symptomatic malignancy, including two brain tumours, one small bowel cancer and four haematological malignancies. ...
In addition, many adenomas were detected in the duodenum, and colorectum and subsequently removed. Seven patients developed a symptom …
Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease.
Wong DR, Coenen MJ, Derijks LJ, Vermeulen SH, van Marrewijk CJ, Klungel OH, Scheffer H, Franke B, Guchelaar HJ, de Jong DJ, Engels LG, Verbeek AL, Hooymans PM; TOPIC Recruitment Team.
Wong DR, et al.
Aliment Pharmacol Ther. 2017 Feb;45(3):391-402. doi: 10.1111/apt.13879. Epub 2016 Dec 12.
Aliment Pharmacol Ther. 2017.
PMID: 27943397
Free article.
Clinical Trial.
Hepatotoxicity was defined by alanine aminotransaminase elevations >2 times the upper normal limit or a ratio of alanine aminotransaminase/alkaline phosphatase 5. RESULTS: Forty-seven patients (17%) presented hepatotoxicity during the first 20 weeks of thiopurine treatm …
Hepatotoxicity was defined by alanine aminotransaminase elevations >2 times the upper normal limit or a ratio of alanine aminotransaminas …
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FDG-PET in the detection of early pancreatic cancer in a BOP hamster model.
van Kouwen MC, Laverman P, van Krieken JH, Oyen WJ, Jansen JB, Drenth JP.
van Kouwen MC, et al.
Nucl Med Biol. 2005 Jul;32(5):445-50. doi: 10.1016/j.nucmedbio.2005.03.002.
Nucl Med Biol. 2005.
PMID: 15982574
The pancreata were histopathologically examined, and the [(18)F]FDG uptake was determined and expressed as percentage of the injected dose per gram tissue (%ID/g). RESULTS: Seven of 55 hamsters developed macroscopic signs of tumor. Histopathological examination revealed PC …
The pancreata were histopathologically examined, and the [(18)F]FDG uptake was determined and expressed as percentage of the injected dose p …
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Noninvasive monitoring of colonic carcinogenesis: feasibility of [(18)F]FDG-PET in the azoxymethane model.
van Kouwen MC, Laverman P, van Krieken JH, Oyen WJ, Nagengast FM, Drenth JP.
van Kouwen MC, et al.
Nucl Med Biol. 2006 Feb;33(2):245-8. doi: 10.1016/j.nucmedbio.2005.11.003.
Nucl Med Biol. 2006.
PMID: 16546679
On histological examination, we found 10 colonic adenocarcinomas (the first being observed at Week 22) and 7 adenocarcinoma in the small bowel. In total, seven colon adenomas were found in five rats, six of which expressed high-grade dysplasia. ...
On histological examination, we found 10 colonic adenocarcinomas (the first being observed at Week 22) and 7 adenocarcinoma in the small bow …
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