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Heme-regulated inhibitor: an overlooked eIF2α kinase in cancer investigations.
Yerlikaya A. Yerlikaya A. Med Oncol. 2022 May 15;39(5):73. doi: 10.1007/s12032-022-01668-1. Med Oncol. 2022. PMID: 35568791 Review.
Heme-regulated inhibitor (HRI) kinase is a serine-threonine kinase, controlling the initiation of protein synthesis via phosphorylating alpha subunit of eIF2 on serine 51 residue, mainly in response to heme deprivation in erythroid cells. ...
Heme-regulated inhibitor (HRI) kinase is a serine-threonine kinase, controlling the initiation of protein synthesis via phosphorylati …
Differential effects of p38 MAP kinase inhibitors SB203580 and SB202190 on growth and migration of human MDA-MB-231 cancer cell line.
Düzgün ŞA, Yerlikaya A, Zeren S, Bayhan Z, Okur E, Boyacı İ. Düzgün ŞA, et al. Cytotechnology. 2017 Aug;69(4):711-724. doi: 10.1007/s10616-017-0079-2. Epub 2017 Apr 9. Cytotechnology. 2017. PMID: 28393288 Free PMC article.
p38 mitogen-activated protein kinase (MAPK) belongs to the MAPK superfamily, phosphorylating serine and/or threonine residues of the target proteins. The activation of p38 MAPK leads to cell growth, differentiation, inflammation, survival or apoptosis. ...
p38 mitogen-activated protein kinase (MAPK) belongs to the MAPK superfamily, phosphorylating serine and/or threonine residues of the …