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Year Number of Results
1972 1
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2002 3
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2006 1
2007 1
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2011 8
2012 3
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49 results

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Page 1
[Case of EGPA and Eosinophilic Chronic Rhinosinusitis Concomitant with IgG4 Related Disease].
Akiyama K, Yonezaki M, Dobashi H, Kameda T, Hoshikawa H, Kadowaki N. Akiyama K, et al. Nihon Jibiinkoka Gakkai Kaiho. 2017 Feb;120(2):123-30. Nihon Jibiinkoka Gakkai Kaiho. 2017. PMID: 30033930 Review. Japanese.
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitis in patients with bronchial asthma and eosinophilic rhinosinusitis. Serum IgG4 levels are markedly elevated in patients with active EGPA, a disease which has been closely associated with IgG4-rela …
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitis in patients with bronchial asthma and eosinophilic rhinosinusi …
Stereoselective interaction of tolvaptan with amiodarone under racemic metabolic impact by CYP3A5 genotypes in heart failure patients.
Akutsu S, Mino Y, Naito T, Hoshikawa K, Saotome M, Maekawa Y, Kawakami J. Akutsu S, et al. Eur J Clin Pharmacol. 2022 Aug;78(8):1311-1320. doi: 10.1007/s00228-022-03341-y. Epub 2022 May 23. Eur J Clin Pharmacol. 2022. PMID: 35604424
Gene polymorphisms of CYP3A5, carbonyl reductase (CBR) 1/3, and ATP-binding cassette subfamily B member (ABCB) 1 were analyzed for their impact on tolvaptan pharmacokinetics. Serum laboratory test values and concomitant use of amiodarone were evaluated as factors related t …
Gene polymorphisms of CYP3A5, carbonyl reductase (CBR) 1/3, and ATP-binding cassette subfamily B member (ABCB) 1 were analyzed for their imp …
Associations of Serum Cytokines, Growth Factors, and High-Sensitivity C-Reactive Protein Levels in Patients with Major Depression with and without Type 2 Diabetes Mellitus: An Explanatory Investigation.
Hoshikawa T, Okamoto N, Natsuyama T, Fujii R, Ikenouchi A, Honma Y, Harada M, Yoshimura R. Hoshikawa T, et al. Neuropsychiatr Dis Treat. 2022 Feb 3;18:173-186. doi: 10.2147/NDT.S350121. eCollection 2022. Neuropsychiatr Dis Treat. 2022. PMID: 35140467 Free PMC article.
In the major depression group, serum IL-6 and hs-CRP levels tended to be higher in patients with type 2 diabetes mellitus than in those without. ...Also, correlations were found between serum levels of cytokines, growth factors, and hs-CRP in patients with major dep …
In the major depression group, serum IL-6 and hs-CRP levels tended to be higher in patients with type 2 diabetes mellitus than in tho …
Effect of acute moderate-intensity cycling on cfDNA levels considering menstrual cycle phases.
Sawai A, Shida T, Hoshikawa Y, Hatanaka S, Ueda M, Kato Y, Tokinoya K, Natsui H, Kawakami Y, Takekoshi K. Sawai A, et al. Front Sports Act Living. 2024 Jan 29;6:1322295. doi: 10.3389/fspor.2024.1322295. eCollection 2024. Front Sports Act Living. 2024. PMID: 38348376 Free PMC article.
No significant phase difference was observed in cfDNA across all time points. cfDNA (menstrual phase: p = 0.028, ovulatory phase: p = 0.018, and luteal phase: p = 0.048) and aromatase concentrations (menstrual phase: p = 0.040, ovulatory phase: p = 0.039, and luteal phase: p = 0. …
No significant phase difference was observed in cfDNA across all time points. cfDNA (menstrual phase: p = 0.028, ovulatory phase: p = 0.018, …
Protective Roles of Endothelial AMP-Activated Protein Kinase Against Hypoxia-Induced Pulmonary Hypertension in Mice.
Omura J, Satoh K, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Otsuki T, Kozu K, Numano K, Suzuki K, Sunamura S, Tatebe S, Aoki T, Sugimura K, Miyata S, Hoshikawa Y, Okada Y, Shimokawa H. Omura J, et al. Circ Res. 2016 Jul 8;119(2):197-209. doi: 10.1161/CIRCRESAHA.115.308178. Epub 2016 May 23. Circ Res. 2016. PMID: 27217398
Importantly, conditioned medium from endothelial cells promoted pulmonary artery smooth muscle cell proliferation, which was further enhanced by the treatment with AMPK inhibitor. Serum levels of inflammatory cytokines, including tumor necrosis factor-alpha and interferon- …
Importantly, conditioned medium from endothelial cells promoted pulmonary artery smooth muscle cell proliferation, which was further enhance …
A machine learning-based treatment prediction model using whole genome variants of hepatitis C virus.
Haga H, Sato H, Koseki A, Saito T, Okumoto K, Hoshikawa K, Katsumi T, Mizuno K, Nishina T, Ueno Y. Haga H, et al. PLoS One. 2020 Nov 5;15(11):e0242028. doi: 10.1371/journal.pone.0242028. eCollection 2020. PLoS One. 2020. PMID: 33152046 Free PMC article.
Using next-generation sequencing technology, we identified hepatitis C virus (HCV) variants resistant to directing-acting antivirals (DAA) by whole genome sequencing of full-length HCV genomes, and applied these variants to various machine-learning algorithms to evaluate a prelim …
Using next-generation sequencing technology, we identified hepatitis C virus (HCV) variants resistant to directing-acting antivirals (DAA) b …
Video-assisted thoracoscopic surgery for ectopic mediastinal parathyroid tumor: subxiphoid and lateral thoracic approach.
Nagano H, Suda T, Ishizawa H, Negi T, Kawai H, Kawakami T, Tochii D, Tochii S, Hoshikawa Y. Nagano H, et al. J Thorac Dis. 2019 Jul;11(7):2932-2938. doi: 10.21037/jtd.2019.07.35. J Thorac Dis. 2019. PMID: 31463122 Free PMC article.
The patient who underwent multi-port mediastinal tumor resection using the lateral thoracic approach reported postoperative pain. Serum calcium levels decreased from 10.561.52 mg/dL preoperatively to 8.960.5 mg/dL postoperatively, and serum phosphorous levels increa …
The patient who underwent multi-port mediastinal tumor resection using the lateral thoracic approach reported postoperative pain. Serum …
Effects of green tea polyphenols on iodide-induced autoimmune thyroiditis in nonobese diabetic mice.
Hoshikawa S, Nakagawa Y, Ozaki H, Takahashi Y, Ito S, Yoshida K, Mori K. Hoshikawa S, et al. Immunol Invest. 2013;42(3):235-46. doi: 10.3109/08820139.2012.753611. Epub 2013 Mar 5. Immunol Invest. 2013. PMID: 23461615
GTPs administration led to an enhanced production of interleukin-10 by concanavalin A-stimulated splenocytes but did not interfere with thyroiditis development. Serum thyroxine levels were not influenced by GTPs. Our data suggest that administration of GTPs may not be an e …
GTPs administration led to an enhanced production of interleukin-10 by concanavalin A-stimulated splenocytes but did not interfere with thyr …
Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: Possible Novel Therapeutic Target.
Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Elias-Al-Mamun M, Siddique MAH, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Saito Y, Hoshikawa Y, Okada Y, Shimokawa H. Kikuchi N, et al. Circulation. 2018 Aug 7;138(6):600-623. doi: 10.1161/CIRCULATIONAHA.117.033113. Circulation. 2018. PMID: 29636330
METHODS: Microarray analyses were used to identify a novel therapeutic target for PAH. In vitro experiments, including lung and serum samples from patients with PAH, cultured PAH-PASMCs, and high-throughput screening of 3336 low-molecular-weight compounds, were used for me …
METHODS: Microarray analyses were used to identify a novel therapeutic target for PAH. In vitro experiments, including lung and serum …
Comparison of Serum Metabolomics Pathways and Patterns between Patients with Major Depressive Disorder with and without Type 2 Diabetes Mellitus: An Exploratory Study.
Okamoto N, Hoshikawa T, Ikenouchi A, Natsuyama T, Fujii R, Igata R, Tesen H, Konishi Y, Honma Y, Harada M, Yoshimura R. Okamoto N, et al. J Integr Neurosci. 2023 Jan 11;22(1):13. doi: 10.31083/j.jin2201013. J Integr Neurosci. 2023. PMID: 36722244 Free article.
METHODS: We performed a metabolomics analysis of serum samples of healthy controls (n = 6), patients with MDD and type 2 diabetes mellitus (n = 13), and patients with MDD without type 2 diabetes mellitus (n = 27). ...Specifically, comorbid type 2 diabetes mellitus could af …
METHODS: We performed a metabolomics analysis of serum samples of healthy controls (n = 6), patients with MDD and type 2 diabetes mel …
49 results