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Year Number of Results
2012 1
2013 2
2014 1
2015 1
2016 1
2017 2
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2019 4
2020 4
2021 2
2022 3
2023 3
2024 0

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Page 1
The interplay between leptin, glucocorticoids, and GLP1 regulates food intake and feeding behaviour.
Perez-Leighton C, Kerr B, Scherer PE, Baudrand R, Cortés V. Perez-Leighton C, et al. Biol Rev Camb Philos Soc. 2023 Dec 10. doi: 10.1111/brv.13039. Online ahead of print. Biol Rev Camb Philos Soc. 2023. PMID: 38072002
Nutritional, endocrine, and neurological signals converge in multiple brain centres to control feeding behaviour and food intake as part of the allostatic regulation of energy balance. Among the several neuroendocrine systems involved, the leptin, glucocorticoid, and gluca …
Nutritional, endocrine, and neurological signals converge in multiple brain centres to control feeding behaviour and food intake as part of …
COVID-19 Severity in Obesity: Leptin and Inflammatory Cytokine Interplay in the Link Between High Morbidity and Mortality.
Maurya R, Sebastian P, Namdeo M, Devender M, Gertler A. Maurya R, et al. Front Immunol. 2021 Jun 18;12:649359. doi: 10.3389/fimmu.2021.649359. eCollection 2021. Front Immunol. 2021. PMID: 34220807 Free PMC article. Review.
Leptin is considered a pleiotropic molecule regulating appetite and immunity. ...Therefore, leptin activity by leptin long-lasting super active antagonist's dysregulation in patients with obesity might contribute to high mortality rates in these patients duri
Leptin is considered a pleiotropic molecule regulating appetite and immunity. ...Therefore, leptin activity by leptin l
DNA methylation changes in genes coding for leptin and insulin receptors during metabolic-altered pregnancies.
Stolzenbach F, Valdivia S, Ojeda-Provoste P, Toledo F, Sobrevia L, Kerr B. Stolzenbach F, et al. Biochim Biophys Acta Mol Basis Dis. 2020 Feb 1;1866(2):165465. doi: 10.1016/j.bbadis.2019.05.001. Epub 2019 May 7. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31075490 Free article. Review.
The most studied receptors involved in the metabolic sensing are the leptin and the insulin receptors. A maternal metabolic disease-like state can alter the expression of these receptors in different organs, including placenta. ...
The most studied receptors involved in the metabolic sensing are the leptin and the insulin receptors. A maternal metabolic disease-l …
Adiponectin, Leptin, and IGF-1 Are Useful Diagnostic and Stratification Biomarkers of NAFLD.
Marques V, Afonso MB, Bierig N, Duarte-Ramos F, Santos-Laso Á, Jimenez-Agüero R, Eizaguirre E, Bujanda L, Pareja MJ, Luís R, Costa A, Machado MV, Alonso C, Arretxe E, Alustiza JM, Krawczyk M, Lammert F, Tiniakos DG, Flehmig B, Cortez-Pinto H, Banales JM, Castro RE, Normann A, Rodrigues CMP. Marques V, et al. Front Med (Lausanne). 2021 Jun 23;8:683250. doi: 10.3389/fmed.2021.683250. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34249975 Free PMC article.
Results: In both cohorts, leptin increased in NAFLD vs. controls (discovery: AUROC 0.88; validation: AUROC 0.83; p < 0.0001). The leptin levels were similar between obese and non-obese healthy controls, suggesting that obesity is not a confounding factor. ...

Results: In both cohorts, leptin increased in NAFLD vs. controls (discovery: AUROC 0.88; validation: AUROC 0.83; p < 0.0001). The

Aldosterone Production and Signaling Dysregulation in Obesity.
Vecchiola A, Lagos CF, Carvajal CA, Baudrand R, Fardella CE. Vecchiola A, et al. Curr Hypertens Rep. 2016 Mar;18(3):20. doi: 10.1007/s11906-016-0626-9. Curr Hypertens Rep. 2016. PMID: 26838033 Review.
Obesity, a current epidemic worldwide, increases aldosterone production by several adipocyte factors such as leptin but is also associated with local aldosterone production. In addition, obesity can modulate MR activation leading to signaling dysregulation and a pro-inflam …
Obesity, a current epidemic worldwide, increases aldosterone production by several adipocyte factors such as leptin but is also assoc …
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice.
Marín-Aguilar F, Lechuga-Vieco AV, Alcocer-Gómez E, Castejón-Vega B, Lucas J, Garrido C, Peralta-Garcia A, Pérez-Pulido AJ, Varela-López A, Quiles JL, Ryffel B, Flores I, Bullón P, Ruiz-Cabello J, Cordero MD. Marín-Aguilar F, et al. Aging Cell. 2020 Jan;19(1):e13050. doi: 10.1111/acel.13050. Epub 2019 Oct 18. Aging Cell. 2020. PMID: 31625260 Free PMC article.
Ablation of NLRP3-inflammasome protected mice from age-related increased insulin sensitivity, reduced IGF-1 and leptin/adiponectin ratio levels, and reduced cardiac damage with protection of the prolongation of the age-dependent PR interval, which is associated with atrial …
Ablation of NLRP3-inflammasome protected mice from age-related increased insulin sensitivity, reduced IGF-1 and leptin/adiponectin ra …
Associations between dietary inflammatory scores and biomarkers of inflammation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
Lécuyer L, Laouali N, Viallon V, Artaud F, Hébert JR, Shivappa N, Agudo A, Tjønneland A, Mellemkjær L, Kaaks R, Katzke VA, Schulze MB, Frenoy P, Mancini FR, De Magistris MS, Macciotta A, Masala G, Agnoli C, Tumino R, Boer JMA, Verschuren WMM, Enget Jensen TM, Olsen KS, Skeie G, Chirlaque MD, Petrova D, Castro-Espin C, Quirós JR, Guevara M, Amiano P, Borné Y, Sandström M, Nilsson LM, Heath AK, Mayen AL, Huybrechts I, Weiderpass E, Boutron-Ruault MC, Dossus L, Rinaldi S, Truong T. Lécuyer L, et al. Clin Nutr. 2023 Jul;42(7):1115-1125. doi: 10.1016/j.clnu.2023.05.012. Epub 2023 May 17. Clin Nutr. 2023. PMID: 37271707 Free article.
Associations between the four scores and C-reactive protein (CRP), interleukin (IL)6, IL10, IL1RA, tumor necrosis factor-alpha (TNFalpha), soluble tumor necrosis factor receptor-1 (sTNFR1), sTNFR2, leptin, soluble leptin receptor (sLeptin R), adiponectin, and High M …
Associations between the four scores and C-reactive protein (CRP), interleukin (IL)6, IL10, IL1RA, tumor necrosis factor-alpha (TNFalpha), s …
Chronic Stress and Ovulatory Dysfunction: Implications in Times of COVID-19.
Vigil P, Meléndez J, Soto H, Petkovic G, Bernal YA, Molina S. Vigil P, et al. Front Glob Womens Health. 2022 May 23;3:866104. doi: 10.3389/fgwh.2022.866104. eCollection 2022. Front Glob Womens Health. 2022. PMID: 35677754 Free PMC article. Review.
During chronic stress, the kisspeptinergic system affects the HPG axis, GnRH pulsatility, and, therefore, ovulation. Leptin, insulin and corticotrophin-releasing hormone (CRH) are thought to be additional key modulators in the behavioral responses to chronic stress and may …
During chronic stress, the kisspeptinergic system affects the HPG axis, GnRH pulsatility, and, therefore, ovulation. Leptin, insulin …
Circulating inflammatory biomarkers, adipokines and breast cancer risk-a case-control study nested within the EPIC cohort.
Cairat M, Rinaldi S, Navionis AS, Romieu I, Biessy C, Viallon V, Olsen A, Tjønneland A, Fournier A, Severi G, Kvaskoff M, Fortner RT, Kaaks R, Aleksandrova K, Schulze MB, Masala G, Tumino R, Sieri S, Grasso C, Mattiello A, Gram IT, Olsen KS, Agudo A, Etxezarreta PA, Sánchez MJ, Santiuste C, Barricarte A, Monninkhof E, Hiensch AE, Muller D, Merritt MA, Travis RC, Weiderpass E, Gunter MJ, Dossus L. Cairat M, et al. BMC Med. 2022 Apr 18;20(1):118. doi: 10.1186/s12916-022-02319-y. BMC Med. 2022. PMID: 35430795 Free PMC article.
Adjustment for BMI strengthened the estimates in premenopausal women [leptin: OR = 0.83 (0.68-1.00), leptin-to-adiponectin ratio: OR = 0.80 (0.66-0.97), CRP: OR = 0.85 (0.72-1.00)] but attenuated the estimates in postmenopausal women [leptin: OR = 1.09 (0.96- …
Adjustment for BMI strengthened the estimates in premenopausal women [leptin: OR = 0.83 (0.68-1.00), leptin-to-adiponectin rat …
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
Schneeberger M, Dietrich MO, Sebastián D, Imbernón M, Castaño C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodríguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M. Schneeberger M, et al. Cell. 2013 Sep 26;155(1):172-87. doi: 10.1016/j.cell.2013.09.003. Cell. 2013. PMID: 24074867 Free PMC article.
Hypothalamic ER stress has emerged as a causative factor for the development of leptin resistance, but the underlying mechanisms are largely unknown. ...This previously unrecognized role for MFN2 argues for a crucial involvement in mediating ER stress-induced leptin
Hypothalamic ER stress has emerged as a causative factor for the development of leptin resistance, but the underlying mechanisms are …
21 results