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Fasciola hepatica expresses multiple alpha- and beta-tubulin isotypes.
Mol Biochem Parasitol. 2008 May;159(1):73-8. doi: 10.1016/j.molbiopara.2008.02.001. Epub 2008 Feb 14.
Mol Biochem Parasitol. 2008.
PMID: 18372053
Free PMC article.
Differential expression of liver fluke β-tubulin isotypes at selected life cycle stages.
Fuchs MA, Ryan LA, Chambers EL, Moore CM, Fairweather I, Trudgett A, Timson DJ, Brennan GP, Hoey EM.
Fuchs MA, et al.
Int J Parasitol. 2013 Dec;43(14):1133-9. doi: 10.1016/j.ijpara.2013.08.007. Epub 2013 Oct 24.
Int J Parasitol. 2013.
PMID: 24162076
We have shown that Fasciola hepatica expresses at least six beta-tubulins in the adult stage of its life cycle, designated F.hep-beta-tub1-6 (Ryan et al., 2008). Here we show that different complements of tubulin isotypes are expressed in different tissues and at different …
We have shown that Fasciola hepatica expresses at least six beta-tubulins in the adult stage of its life cycle, designated F.hep-beta-tub1-6 …
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Liver fluke β-tubulin isotype 2 binds albendazole and is thus a probable target of this drug.
Chambers E, Ryan LA, Hoey EM, Trudgett A, McFerran NV, Fairweather I, Timson DJ.
Chambers E, et al.
Parasitol Res. 2010 Oct;107(5):1257-64. doi: 10.1007/s00436-010-1997-5. Epub 2010 Jul 31.
Parasitol Res. 2010.
PMID: 20676683
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The contribution of key hydrophobic residues in ecotin to enzyme-inhibitor complex stability.
McCrudden MT, Ryan LA, Turkington P, Timson DJ.
McCrudden MT, et al.
J Enzyme Inhib Med Chem. 2009 Dec;24(6):1207-10. doi: 10.3109/14756360902779458.
J Enzyme Inhib Med Chem. 2009.
PMID: 19912053
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