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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1951 1
1954 3
1963 2
1964 2
1965 1
1966 2
1967 1
1968 2
1969 7
1970 5
1971 9
1972 8
1973 4
1974 1
1975 3
1977 6
1978 3
1979 1
1980 3
1981 3
1982 3
1983 3
1984 1
1985 4
1986 1
1987 4
1988 2
1989 5
1991 2
1992 7
1993 2
1994 3
1995 6
1996 4
1997 2
1998 7
1999 6
2000 6
2001 11
2002 12
2003 12
2004 5
2005 10
2006 15
2007 13
2008 13
2009 15
2010 19
2011 15
2012 23
2013 26
2014 33
2015 46
2016 50
2017 51
2018 61
2019 58
2020 78
2021 93
2022 108
2023 92
2024 25

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914 results

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Page 1
Mechanisms of antidiabetic effects of flavonoid rutin.
Ghorbani A. Ghorbani A. Biomed Pharmacother. 2017 Dec;96:305-312. doi: 10.1016/j.biopha.2017.10.001. Epub 2017 Oct 7. Biomed Pharmacother. 2017. PMID: 29017142 Review.
In this review, the antihyperglycemic property of rutin and its protective effects against the development of diabetic complications are discussed. ...Taken together, the results of current experimental studies support the potential of rutin to prevent or tre …
In this review, the antihyperglycemic property of rutin and its protective effects against the development of diabetic complicatio …
Regulated rutin co-administration reverses mitochondrial-mediated apoptosis in Plasmodium berghei-infected mice.
Oludele OJ, Adisa BA, Olufunso OO. Oludele OJ, et al. Biochem Biophys Res Commun. 2020 Feb 5;522(2):328-334. doi: 10.1016/j.bbrc.2019.11.067. Epub 2019 Nov 22. Biochem Biophys Res Commun. 2020. PMID: 31767147
Malarial infection causes apoptosis in hepatocytes. However, it is not known if co-administration of antimalarial drug with rutin will reverse the apoptotic effects of malarial infection. ...AM and DP significantly increased caspases 3 and 9 activities, enhanced mAT …
Malarial infection causes apoptosis in hepatocytes. However, it is not known if co-administration of antimalarial drug with rutin …
Lithium co-administration with rutin improves post-stroke neurological outcomes via suppressing Gsk-3beta activity in a rat model.
Rana AK, Kumar R, Shukla DN, Singh D. Rana AK, et al. Free Radic Biol Med. 2023 Oct;207:107-119. doi: 10.1016/j.freeradbiomed.2023.07.004. Epub 2023 Jul 4. Free Radic Biol Med. 2023. PMID: 37414348
Reperfusion is the only therapeutic option with a lot of side effects. In the current study, we investigated the efficacy of rutin and lithium co-treatment in improving post-stroke neurological outcomes in a transient global cerebral ischemia-reperfusion injury rat …
Reperfusion is the only therapeutic option with a lot of side effects. In the current study, we investigated the efficacy of rutin an …
Rutin co-treatment prevented cognitive impairment/depression-like behavior and decreased IDO activation following 35 days of ethanol administration in male Wistar rats.
Ebokaiwe AP, Obasi DO, Obeten U, Onyemuche T. Ebokaiwe AP, et al. Alcohol. 2023 Feb;106:22-29. doi: 10.1016/j.alcohol.2022.10.002. Epub 2022 Oct 25. Alcohol. 2023. PMID: 36306976
Herein, we investigate the impact of rutin on ethanol-induced cognitive impairment and depressive-like effects in rats and the involvement of the indoleaminergic pathway. ...Additionally, altered behavioral indices were prevented by rutin co-exposure. Taken t …
Herein, we investigate the impact of rutin on ethanol-induced cognitive impairment and depressive-like effects in rats and the involv …
Co-loading of Temozolomide with Oleuropein or rutin into polylactic acid core-shell nanofiber webs inhibit glioblastoma cell by controlled release.
Ercelik M, Tekin C, Parin FN, Mutlu B, Dogan HY, Tezcan G, Aksoy SA, Gurbuz M, Yildirim K, Bekar A, Kocaeli H, Taskapilioglu MO, Eser P, Tunca B. Ercelik M, et al. Int J Biol Macromol. 2023 Dec 31;253(Pt 2):126722. doi: 10.1016/j.ijbiomac.2023.126722. Epub 2023 Sep 8. Int J Biol Macromol. 2023. PMID: 37673167
In this study, we developed a nanofiber-based local therapy against GB cells using Oleuropein (OL), and rutin and their combinations with Temozolomide (TMZ). The polylactic acid (PLA) core-shell nanofiber webs were encapsulated with OL (PLA(OL)), rutin (PLA(rutin …
In this study, we developed a nanofiber-based local therapy against GB cells using Oleuropein (OL), and rutin and their combinations …
Brain-Penetration and Neuron-Targeting DNA Nanoflowers Co-Delivering miR-124 and Rutin for Synergistic Therapy of Alzheimer's Disease.
Ouyang Q, Liu K, Zhu Q, Deng H, Le Y, Ouyang W, Yan X, Zhou W, Tong J. Ouyang Q, et al. Small. 2022 Apr;18(14):e2107534. doi: 10.1002/smll.202107534. Epub 2022 Feb 19. Small. 2022. PMID: 35182016
The DFs are further modified with RVG29 peptide to simultaneously realize brain-blood barrier (BBB) penetration and neuron targeting. Meanwhile, Rutin, a small molecular ancillary drug, is co-loaded into the DFs structure via its intercalation into the double strand …
The DFs are further modified with RVG29 peptide to simultaneously realize brain-blood barrier (BBB) penetration and neuron targeting. Meanwh …
Carrier-Free Nanodrug Based on Co-Assembly of Methylprednisolone Dimer and Rutin for Combined Treatment of Spinal Cord Injury.
Wang H, Lin F, Wu Y, Guo W, Chen X, Xiao C, Chen M. Wang H, et al. ACS Nano. 2023 Jul 11;17(13):12176-12187. doi: 10.1021/acsnano.3c00360. Epub 2023 Jun 30. ACS Nano. 2023. PMID: 37387550
Methylprednisolone (MP) is the most commonly used clinical anti-inflammatory drug for SCI treatment, but high doses are typically required that can cause severe side effects. Here, we developed a carrier-free thioketal linked MP dimer@rutin nanoparticles (MP(2)-TK@RU NPs) …
Methylprednisolone (MP) is the most commonly used clinical anti-inflammatory drug for SCI treatment, but high doses are typically required t …
Compartmentalized chitooligosaccharide/ferritin particles for controlled co-encapsulation of curcumin and rutin.
Chen H, Han X, Fu Y, Dai H, Wang H, Ma L, Zhang Y. Chen H, et al. Carbohydr Polym. 2022 Aug 15;290:119484. doi: 10.1016/j.carbpol.2022.119484. Epub 2022 Apr 13. Carbohydr Polym. 2022. PMID: 35550771
By taking advantage of the multiple compartments of COS/Fn particles, curcumin and rutin molecules can be simultaneously encapsulated within COS/Fn particles in a compartmentalized manner. More importantly, the loading ratio of curcumin and rutin within COS/Fn parti …
By taking advantage of the multiple compartments of COS/Fn particles, curcumin and rutin molecules can be simultaneously encapsulated …
A computational-based approach to fabricate Ceritinib co-amorphous system using a novel co-former Rutin for bioavailability enhancement.
Yarlagadda DL, Anand VSK, Nair AR, Dengale SJ, Pandiyan S, Mehta CH, Manandhar S, Nayak UY, Bhat K. Yarlagadda DL, et al. Eur J Pharm Biopharm. 2023 Sep;190:220-230. doi: 10.1016/j.ejpb.2023.07.019. Epub 2023 Jul 29. Eur J Pharm Biopharm. 2023. PMID: 37524214
Rutin (RTH) was selected as a co-former for CRT CAMs using the solvent evaporation method to anticipate simultaneous improvement of solubility and bioavailability. ...The co-amorphous materials exhibited physical stability for up to 4 months under dry conditi …
Rutin (RTH) was selected as a co-former for CRT CAMs using the solvent evaporation method to anticipate simultaneous improveme …
Rutin and Selenium Co-administration Reverse 3-Nitropropionic Acid-Induced Neurochemical and Molecular Impairments in a Mouse Model of Huntington's Disease.
Abdelfattah MS, Badr SEA, Lotfy SA, Attia GH, Aref AM, Abdel Moneim AE, Kassab RB. Abdelfattah MS, et al. Neurotox Res. 2020 Jan;37(1):77-92. doi: 10.1007/s12640-019-00086-y. Epub 2019 Jul 22. Neurotox Res. 2020. PMID: 31332714
Systemic administration of 3-nitropropionic acid (3-NPA) is commonly used to induce Huntington's disease (HD)-like symptoms in experimental animals. Here, the potential neuroprotective efficiency of rutin and selenium (RSe) co-administration on 3-NPA-induced HD-like …
Systemic administration of 3-nitropropionic acid (3-NPA) is commonly used to induce Huntington's disease (HD)-like symptoms in experimental …
914 results