Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice.
Vogel KS, Perez M, Momand JR, Acevedo-Torres K, Hildreth K, Garcia RA, Torres-Ramos CA, Ayala-Torres S, Prihoda TJ, McMahan CA, Walter CA.
Vogel KS, et al. Among authors: garcia ra.
Mol Reprod Dev. 2011 Dec;78(12):906-19. doi: 10.1002/mrd.21374. Epub 2011 Sep 14.
Mol Reprod Dev. 2011.
PMID: 21919107
Free PMC article.
Mutant frequency increased earlier in spermatogenic cells from Apex1(+/-) mice (by 6 months of age). Nuclear DNA damage increased with age in the spermatogenic lineage for both wild-type and Apex1(+/-) mice. ...
Mutant frequency increased earlier in spermatogenic cells from Apex1(+/-) mice (by 6 months of age). Nuclear DNA damage increased wit …