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Year Number of Results
1961 1
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1979 3
1981 2
1982 2
1983 4
1984 3
1985 4
1986 4
1987 2
1988 2
1989 4
1990 3
1991 8
1992 8
1993 16
1994 16
1995 17
1996 17
1997 9
1998 11
1999 21
2000 32
2001 29
2002 33
2003 32
2004 34
2005 35
2006 34
2007 38
2008 42
2009 44
2010 41
2011 76
2012 73
2013 62
2014 96
2015 139
2016 165
2017 176
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2019 157
2020 180
2021 233
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2024 90

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Page 1
Showing results for peter solid
Search for peter solik instead (2 results)
Cellular networks controlling T cell persistence in adoptive cell therapy.
Chan JD, Lai J, Slaney CY, Kallies A, Beavis PA, Darcy PK. Chan JD, et al. Nat Rev Immunol. 2021 Dec;21(12):769-784. doi: 10.1038/s41577-021-00539-6. Epub 2021 Apr 20. Nat Rev Immunol. 2021. PMID: 33879873 Review.
This Review discusses existing barriers and strategies to overcome them for successful T cell expansion and persistence in the context of adoptive T cell immunotherapy for solid cancers....
This Review discusses existing barriers and strategies to overcome them for successful T cell expansion and persistence in the context of ad …
Single-cell protein expression profiling resolves circulating and resident memory T cell diversity across tissues and infection contexts.
Evrard M, Becht E, Fonseca R, Obers A, Park SL, Ghabdan-Zanluqui N, Schroeder J, Christo SN, Schienstock D, Lai J, Burn TN, Clatch A, House IG, Beavis P, Kallies A, Ginhoux F, Mueller SN, Gottardo R, Newell EW, Mackay LK. Evrard M, et al. Immunity. 2023 Jul 11;56(7):1664-1680.e9. doi: 10.1016/j.immuni.2023.06.005. Epub 2023 Jun 30. Immunity. 2023. PMID: 37392736
Here, we utilized an antibody screening platform and machine learning prediction pipeline (InfinityFlow) to profile >200 proteins in T(CIRCM) and T(RM) cells in solid organs and barrier locations. High-dimensional analyses revealed unappreciated heterogeneity within T(C …
Here, we utilized an antibody screening platform and machine learning prediction pipeline (InfinityFlow) to profile >200 proteins in T(CI …
Progression to Metastasis of Solid Cancer.
Zacksenhaus E, Egan SE. Zacksenhaus E, et al. Cancers (Basel). 2021 Feb 10;13(4):717. doi: 10.3390/cancers13040717. Cancers (Basel). 2021. PMID: 33578666 Free PMC article.
Metastatic dissemination of cancer cells, their colonization at distal sites, and ultimate disruption of tissue physiology are the root causes of most deaths from solid cancers, particularly in tumor types where the primary lesion can be easily dissected and discarded [... …
Metastatic dissemination of cancer cells, their colonization at distal sites, and ultimate disruption of tissue physiology are the root caus …
Applications of solid-state NMR to membrane proteins.
Ladizhansky V. Ladizhansky V. Biochim Biophys Acta Proteins Proteom. 2017 Nov;1865(11 Pt B):1577-1586. doi: 10.1016/j.bbapap.2017.07.004. Epub 2017 Jul 12. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 28709996 Review.
We highlight recent advances in applications of solid-state NMR to membrane proteins, specifically focusing on the recent developments in the field of Dynamic Nuclear Polarization, proton detection, and solid-state NMR applications in situ (in cell membranes). This …
We highlight recent advances in applications of solid-state NMR to membrane proteins, specifically focusing on the recent development …
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy.
Chan JD, Scheffler CM, Munoz I, Sek K, Lee JN, Huang YK, Yap KM, Saw NYL, Li J, Chen AXY, Chan CW, Derrick EB, Todd KL, Tong J, Dunbar PA, Li J, Hoang TX, de Menezes MN, Petley EV, Kim JS, Nguyen D, Leung PSK, So J, Deguit C, Zhu J, House IG, Kats LM, Scott AM, Solomon BJ, Harrison SJ, Oliaro J, Parish IA, Quinn KM, Neeson PJ, Slaney CY, Lai J, Beavis PA, Darcy PK. Chan JD, et al. Nature. 2024 May;629(8010):201-210. doi: 10.1038/s41586-024-07242-1. Epub 2024 Apr 10. Nature. 2024. PMID: 38600376 Free PMC article.
We therefore sought to identify transcription factors that could enhance CAR T cell fitness and efficacy against solid tumours. Here we show that overexpression of FOXO1 promotes a stem-like phenotype in CAR T cells derived from either healthy human donors or patients, whi …
We therefore sought to identify transcription factors that could enhance CAR T cell fitness and efficacy against solid tumours. Here …
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Vervoort SJ, Welsh SA, Devlin JR, Barbieri E, Knight DA, Offley S, Bjelosevic S, Costacurta M, Todorovski I, Kearney CJ, Sandow JJ, Fan Z, Blyth B, McLeod V, Vissers JHA, Pavic K, Martin BP, Gregory G, Demosthenous E, Zethoven M, Kong IY, Hawkins ED, Hogg SJ, Kelly MJ, Newbold A, Simpson KJ, Kauko O, Harvey KF, Ohlmeyer M, Westermarck J, Gray N, Gardini A, Johnstone RW. Vervoort SJ, et al. Cell. 2021 Jun 10;184(12):3143-3162.e32. doi: 10.1016/j.cell.2021.04.022. Epub 2021 May 17. Cell. 2021. PMID: 34004147 Free PMC article.
Pharmacological PP2A activation synergizes with CDK9 inhibition to kill both leukemic and solid tumor cells, providing therapeutic benefit in vivo. These data demonstrate that fine control of gene expression relies on the balance between kinase and phosphatase activity thr …
Pharmacological PP2A activation synergizes with CDK9 inhibition to kill both leukemic and solid tumor cells, providing therapeutic be …
Immune profiling of pediatric solid tumors.
Terry RL, Meyran D, Ziegler DS, Haber M, Ekert PG, Trapani JA, Neeson PJ. Terry RL, et al. J Clin Invest. 2020 Jul 1;130(7):3391-3402. doi: 10.1172/JCI137181. J Clin Invest. 2020. PMID: 32538896 Free PMC article. Review.
Pediatric cancers, particularly high-risk solid tumors, urgently need effective and specific therapies. Their outlook has not appreciably improved in decades. ...Here, we review the current status of immune profiling of pediatric solid tumors, with emphasis on tumor …
Pediatric cancers, particularly high-risk solid tumors, urgently need effective and specific therapies. Their outlook has not appreci …
Weaponizing natural killer cells for solid cancer immunotherapy.
Wong JKM, Dolcetti R, Rhee H, Simpson F, Souza-Fonseca-Guimaraes F. Wong JKM, et al. Trends Cancer. 2023 Feb;9(2):111-121. doi: 10.1016/j.trecan.2022.10.009. Epub 2022 Nov 12. Trends Cancer. 2023. PMID: 36379852 Review.
Enhancing natural killer (NK) cell-based innate immunity has become a promising strategy for immunotherapy against hard-to-cure solid cancers. Monoclonal antibody (mAb) therapy has been used to activate NK-cell-mediated antibody-dependent cellular cytotoxicity (ADCC) towar …
Enhancing natural killer (NK) cell-based innate immunity has become a promising strategy for immunotherapy against hard-to-cure solid …
An Update on Immunotherapy for Solid Tumors: A Review.
Pham T, Roth S, Kong J, Guerra G, Narasimhan V, Pereira L, Desai J, Heriot A, Ramsay R. Pham T, et al. Ann Surg Oncol. 2018 Oct;25(11):3404-3412. doi: 10.1245/s10434-018-6658-4. Epub 2018 Jul 23. Ann Surg Oncol. 2018. PMID: 30039324 Review.
In recent years, it has been demonstrated that immunotherapy is an effective strategy for the management of solid tumors. The origins of immunotherapy can be traced back to the work of William Coley, who elicited an immune response against sarcoma by injecting patients wit …
In recent years, it has been demonstrated that immunotherapy is an effective strategy for the management of solid tumors. The origins …
2,268 results