Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.
Pain. 2011.
PMID: 21353389
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| 2024 | 80 |
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Antinociception induced by civamide, an orally active capsaicin analogue.
Pain. 1997.
PMID: 9231875
Pain and itch outcome trajectories differ among European American and African American survivors of major thermal burn injury.
Pain. 2017.
PMID: 28796116
Free PMC article.
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Guideline summary review: an evidence-based clinical guideline for the diagnosis and treatment of low back pain.
Spine J. 2020 Jul;20(7):998-1024. doi: 10.1016/j.spinee.2020.04.006. Epub 2020 Apr 22.
Spine J. 2020.
PMID: 32333996
Review.
BACKGROUND CONTEXT: The North American Spine Society's (NASS) Evidence Based Clinical Guideline for the Diagnosis and Treatment of Low Back Pain features evidence-based recommendations for diagnosing and treating adult patients with nonspecific low back pain. ...STU …
BACKGROUND CONTEXT: The North American Spine Society's (NASS) Evidence Based Clinical Guideline for the Diagnosis and Treatment of Low Back …
Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities.
Lancet Oncol. 2022 Feb;23(2):e62-e74. doi: 10.1016/S1470-2045(21)00596-9.
Lancet Oncol. 2022.
PMID: 35114133
Free PMC article.
Review.
In this Review, we describe the foundational, translational, and clinical advances illustrating how nerves contribute to tumour proliferation, stress adaptation, immunomodulation, metastasis, electrical hyperactivity and seizures, and neuropathic pain. Collectively, this e …
In this Review, we describe the foundational, translational, and clinical advances illustrating how nerves contribute to tumour proliferatio …
Bacteria activate sensory neurons that modulate pain and inflammation.
Nature. 2013 Sep 5;501(7465):52-7. doi: 10.1038/nature12479. Epub 2013 Aug 21.
Nature. 2013.
PMID: 23965627
Free PMC article.
Nociceptor sensory neurons are specialized to detect potentially damaging stimuli, protecting the organism by initiating the sensation of pain and eliciting defensive behaviours. Bacterial infections produce pain by unknown molecular mechanisms, although they are pr …
Nociceptor sensory neurons are specialized to detect potentially damaging stimuli, protecting the organism by initiating the sensation of …
The relationships between low back pain and lumbar lordosis: a systematic review and meta-analysis.
Spine J. 2017 Aug;17(8):1180-1191. doi: 10.1016/j.spinee.2017.04.034. Epub 2017 May 2.
Spine J. 2017.
PMID: 28476690
Review.
BACKGROUND CONTEXT: Clinicians regard lumbar lordotic curvature (LLC) with respect to low back pain (LBP) in a contradictory fashion. The time-honored point of view is that LLC itself, or its increment, causes LBP. ...
BACKGROUND CONTEXT: Clinicians regard lumbar lordotic curvature (LLC) with respect to low back pain (LBP) in a contradictory fashion. …
Effect of Music Therapy on Pain After Orthopedic Surgery-A Systematic Review and Meta-Analysis.
Pain Pract. 2020 Apr;20(4):422-436. doi: 10.1111/papr.12864. Epub 2020 Jan 9.
Pain Pract. 2020.
PMID: 31785131
BACKGROUND: Although music interventions on postoperative pain (POP) have positive effects, limited research has focused on systematic reviews and meta-analyses of its efficacy for orthopedic patients. ...A standard mean difference (SMD) with 95% confidence intervals (CIs) …
BACKGROUND: Although music interventions on postoperative pain (POP) have positive effects, limited research has focused on systemati …
Clinical Efficacy and Safety of the Intra-articular Injection of Autologous Adipose-Derived Mesenchymal Stem Cells for Knee Osteoarthritis: A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial.
Am J Sports Med. 2023 Jul;51(9):2243-2253. doi: 10.1177/03635465231179223. Epub 2023 Jun 21.
Am J Sports Med. 2023.
PMID: 37345256
Clinical Trial.
The primary endpoints were improvements in 100-mm visual analog scale (VAS) for pain and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for function at 6 months after the injection. ...CONCLUSION: Intra-articular injection of autologous culture-expa …
The primary endpoints were improvements in 100-mm visual analog scale (VAS) for pain and Western Ontario and McMaster Universities Os …
Biology and pathophysiology of symptomatic neuromas.
Pain. 2024 Mar 1;165(3):550-564. doi: 10.1097/j.pain.0000000000003055. Epub 2023 Oct 17.
Pain. 2024.
PMID: 37851396
Review.
This is not only caused by a disruption in motor and sensory function from the underlying nerve injury but also by the debilitating effects of neuropathic pain resulting from symptomatic neuromas. A wide range of surgical and therapeutic modalities have been introduced to …
This is not only caused by a disruption in motor and sensory function from the underlying nerve injury but also by the debilitating effects …
Elastic Dynamic Sling on Subluxation of Hemiplegic Shoulder in Patients with Subacute Stroke: A Multicenter Randomized Controlled Trial.
Int J Environ Res Public Health. 2022 Aug 12;19(16):9975. doi: 10.3390/ijerph19169975.
Int J Environ Res Public Health. 2022.
PMID: 36011613
Free PMC article.
Clinical Trial.
AIM: This study aimed to investigate whether there is a difference in the subluxation distance, pain, and functional level of the hemiplegic upper extremity among patients with two different shoulder orthoses. ...The secondary outcomes were upper-extremity function, muscle …
AIM: This study aimed to investigate whether there is a difference in the subluxation distance, pain, and functional level of the hem …
Office Evaluation of Pelvic Pain.
Phys Med Rehabil Clin N Am. 2017 Aug;28(3):461-476. doi: 10.1016/j.pmr.2017.03.012.
Phys Med Rehabil Clin N Am. 2017.
PMID: 28676359
Review.
The history and physical examination are important keys to diagnosis and treatment of patients with chronic pelvic pain. The comprehensive history should include questioning regarding patient's pain complaint and a thorough history and review of any body system that …
The history and physical examination are important keys to diagnosis and treatment of patients with chronic pelvic pain. The comprehe …
An Innovative Pain Control Method Using Peripheral Nerve Block and Patient-Controlled Analgesia With Ketorolac After Bone Surgery in the Ankle Area: A Prospective Study.
J Foot Ankle Surg. 2020 Jul-Aug;59(4):698-703. doi: 10.1053/j.jfas.2019.12.001. Epub 2020 Feb 10.
J Foot Ankle Surg. 2020.
PMID: 32057624
All operations were performed under anesthetic PNB, and additional PNB was given for pain control 11 hours after preoperative PNB. An additional PCA with ketorolac, started before rebound pain was experienced, was used for pain control in group A (49 patients …
All operations were performed under anesthetic PNB, and additional PNB was given for pain control 11 hours after preoperative PNB. An …
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