FDX1 regulates cellular protein lipoylation through direct binding to LIAS.
Dreishpoon MB, Bick NR, Petrova B, Warui DM, Cameron A, Booker SJ, Kanarek N, Golub TR, Tsvetkov P.
Dreishpoon MB, et al.
bioRxiv [Preprint]. 2023 Feb 4:2023.02.03.526472. doi: 10.1101/2023.02.03.526472.
bioRxiv. 2023.
PMID: 36778498
Free PMC article.
Updated.
Preprint.
Metabolite profiling revealed that the predominant cellular metabolic outcome of FDX1 loss-of-function is manifested through the regulation of the four lipoylation-dependent enzymes ultimately resulting in loss of cellular respiration and sensitivity to mild glucose starvation. T …
Metabolite profiling revealed that the predominant cellular metabolic outcome of FDX1 loss-of-function is manifested through the regulation …