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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
2006 2
2007 1
2014 1
2015 1
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2018 2
2019 3
2020 2
2021 2
2024 0

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14 results

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Page 1
New Vision in Photoprotection and Photorepair.
Leccia MT, Lebbe C, Claudel JP, Narda M, Basset-Seguin N. Leccia MT, et al. Dermatol Ther (Heidelb). 2019 Mar;9(1):103-115. doi: 10.1007/s13555-019-0282-5. Epub 2019 Jan 23. Dermatol Ther (Heidelb). 2019. PMID: 30674003 Free PMC article. Review.
Newer options that aim to help repair damaged DNA may have an important role in reducing the incidence of chronic sun exposure-related photoaging and non-melanoma skin cancers. Photolyase, which is capable of repairing cyclobutane dimers formed as a result of DNA irradiati …
Newer options that aim to help repair damaged DNA may have an important role in reducing the incidence of chronic sun exposure-related photo …
Homotransfer of FRET Reporters for Live Cell Imaging.
Snell NE, Rao VP, Seckinger KM, Liang J, Leser J, Mancini AE, Rizzo MA. Snell NE, et al. Biosensors (Basel). 2018 Oct 11;8(4):89. doi: 10.3390/bios8040089. Biosensors (Basel). 2018. PMID: 30314323 Free PMC article. Review.
These include enhanced signal-to-noise, greater compatibility with other optical sensors and modulators, and new design strategies based upon the clustering or dimerization of singly-labeled sensors. Here, we discuss the theoretical basis for measuring homotransfer using p …
These include enhanced signal-to-noise, greater compatibility with other optical sensors and modulators, and new design strategies based upo …
Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM.
Ripin N, Boudet J, Duszczyk MM, Hinniger A, Faller M, Krepl M, Gadi A, Schneider RJ, Šponer J, Meisner-Kober NC, Allain FH. Ripin N, et al. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2935-2944. doi: 10.1073/pnas.1808696116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718402 Free PMC article.
This structure together with biophysical methods and cell-culture assays revealed the mechanism of RRM3 ARE recognition and dimerization. While multiple RNA motifs can be bound, recognition of the canonical AUUUA pentameric motif is possible by binding to two registers. .. …
This structure together with biophysical methods and cell-culture assays revealed the mechanism of RRM3 ARE recognition and dimerization …
Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation.
Zhao P, Liu ID, Hodgin JB, Benke PI, Selva J, Torta F, Wenk MR, Endrizzi JA, West O, Ou W, Tang E, Goh DL, Tay SK, Yap HK, Loh A, Weaver N, Sullivan B, Larson A, Cooper MA, Alhasan K, Alangari AA, Salim S, Gumus E, Chen K, Zenker M, Hildebrandt F, Saba JD. Zhao P, et al. J Inherit Metab Dis. 2020 Sep;43(5):1131-1142. doi: 10.1002/jimd.12238. Epub 2020 May 4. J Inherit Metab Dis. 2020. PMID: 32233035 Free PMC article.
One responsive patient is homozygous for an SPL R222Q variant present in almost 30% of SPLIS patients. Molecular modeling suggests the variant distorts the dimer interface which could be overcome by cofactor supplementation. ...
One responsive patient is homozygous for an SPL R222Q variant present in almost 30% of SPLIS patients. Molecular modeling suggests the varia …
Oligomannosidic glycans at Asn-110 are essential for secretion of human diamine oxidase.
Gludovacz E, Maresch D, Lopes de Carvalho L, Puxbaum V, Baier LJ, Sützl L, Guédez G, Grünwald-Gruber C, Ulm B, Pils S, Ristl R, Altmann F, Jilma B, Salminen TA, Borth N, Boehm T. Gludovacz E, et al. J Biol Chem. 2018 Jan 19;293(3):1070-1087. doi: 10.1074/jbc.M117.814244. Epub 2017 Nov 29. J Biol Chem. 2018. PMID: 29187599 Free PMC article.
Because of their locations in the DAO structure, Asn-538 and Asn-745 glycosylations might be important for efficient DAO dimer formation. These functional results are reflected in the high evolutionary conservation of all four glycosylation sites. ...
Because of their locations in the DAO structure, Asn-538 and Asn-745 glycosylations might be important for efficient DAO dimer format …
Acute thrombotic manifestations of coronavirus disease 2019 infection: Experience at a large New York City health care system.
Ilonzo N, Rao A, Safir S, Vouyouka A, Phair J, Baldwin M, Ting W, Soundararajan K, Han D, Tadros R, Marin M, Faries P. Ilonzo N, et al. J Vasc Surg. 2021 Mar;73(3):789-796. doi: 10.1016/j.jvs.2020.08.038. Epub 2020 Sep 1. J Vasc Surg. 2021. PMID: 32882350 Free PMC article.
Several markers were markedly abnormal in both arterial and venous cases, including an elevated neutrophil/lymphocyte ratio (8.8) and D-dimer level (4.9 mug/mL). Operative intervention included percutaneous angiography in 25.00% of patients and open surgical embolectomy in …
Several markers were markedly abnormal in both arterial and venous cases, including an elevated neutrophil/lymphocyte ratio (8.8) and D-d …
Impact of COVID-19 on Patients with Cancer Receiving Immune Checkpoint Inhibitors.
Bui AN, Tyan K, Giobbie-Hurder A, Klein IA, Manos MP, Zubiri L, Reynolds K, Grover S, Weinhouse GL, Ott PA, LeBoeuf NR, Rahma O. Bui AN, et al. J Immunother Precis Oncol. 2021 May 14;4(2):35-44. doi: 10.36401/JIPO-20-34. eCollection 2021 May. J Immunother Precis Oncol. 2021. PMID: 35663537 Free PMC article.
Patients with ICIs had significantly higher platelet (p = 0.017) and D-dimer (p = 0.037) levels. Elevated troponin levels (p = 0.01) were associated with COVID-19 death in patients using ICI. ...
Patients with ICIs had significantly higher platelet (p = 0.017) and D-dimer (p = 0.037) levels. Elevated troponin levels (p = 0.01) …
The Structural Versatility of the BTB Domains of KCTD Proteins and Their Recognition of the GABAB Receptor.
Balasco N, Smaldone G, Vitagliano L. Balasco N, et al. Biomolecules. 2019 Jul 31;9(8):323. doi: 10.3390/biom9080323. Biomolecules. 2019. PMID: 31370201 Free PMC article.
To gain insights into this intriguing aspect, we performed extensive molecular dynamics simulations on several BTB domains of KCTD proteins in different oligomeric states (monomers, dimers, tetramers, and open/close pentamers). These studies indicate that KCTD-BTB domains …
To gain insights into this intriguing aspect, we performed extensive molecular dynamics simulations on several BTB domains of KCTD proteins …
Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR.
Meisner NC, Hintersteiner M, Mueller K, Bauer R, Seifert JM, Naegeli HU, Ottl J, Oberer L, Guenat C, Moss S, Harrer N, Woisetschlaeger M, Buehler C, Uhl V, Auer M. Meisner NC, et al. Nat Chem Biol. 2007 Aug;3(8):508-15. doi: 10.1038/nchembio.2007.14. Epub 2007 Jul 15. Nat Chem Biol. 2007. PMID: 17632515
A mathematical and experimental analysis of the compounds' mode of action suggests that HuR homodimerizes before RNA binding and that the compounds interfere with the formation of HuR dimers. Our results demonstrate the chemical drugability of HuR; to our knowledge HuR is …
A mathematical and experimental analysis of the compounds' mode of action suggests that HuR homodimerizes before RNA binding and that the co …
Identification of new mutations in the Cu/Zn superoxide dismutase gene of patients with familial amyotrophic lateral sclerosis.
Pramatarova A, Figlewicz DA, Krizus A, Han FY, Ceballos-Picot I, Nicole A, Dib M, Meininger V, Brown RH, Rouleau GA. Pramatarova A, et al. Am J Hum Genet. 1995 Mar;56(3):592-6. Am J Hum Genet. 1995. PMID: 7887412 Free PMC article.
One of them affects a highly conserved amino acid involved in dimer contact, and the other one affects the active-site loop of the enzyme. ...
One of them affects a highly conserved amino acid involved in dimer contact, and the other one affects the active-site loop of the en …
14 results