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Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism.
Ertel A, Tsirigos A, Whitaker-Menezes D, Birbe RC, Pavlides S, Martinez-Outschoorn UE, Pestell RG, Howell A, Sotgia F, Lisanti MP. Ertel A, et al. Cell Cycle. 2012 Jan 15;11(2):253-63. doi: 10.4161/cc.11.2.19006. Epub 2012 Jan 15. Cell Cycle. 2012. PMID: 22234241 Free PMC article.
Ron DePinho (MD Anderson) and Craig Thomspson (Sloan-Kettering) that are also consistent with this new hypothesis, linking cancer progression with metabolic aging. Using data mining and bioinformatics approaches, we also provide key evidence of a role for PGC1a/NRF1 signal …
Ron DePinho (MD Anderson) and Craig Thomspson (Sloan-Kettering) that are also consistent with this new hypothesis, linking cancer progressio …
Mitochondrial markers predict recurrence, metastasis and tamoxifen-resistance in breast cancer patients: Early detection of treatment failure with companion diagnostics.
Sotgia F, Fiorillo M, Lisanti MP. Sotgia F, et al. Oncotarget. 2017 Jul 27;8(40):68730-68745. doi: 10.18632/oncotarget.19612. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978152 Free PMC article.
Here, we used a data-mining and informatics approach to discover new biomarkers of resistance to hormonal therapy in breast cancer. ...
Here, we used a data-mining and informatics approach to discover new biomarkers of resistance to hormonal therapy in breast cancer. . …