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Year Number of Results
2004 1
2005 1
2007 2
2010 1
2011 1
2012 4
2013 4
2014 1
2015 4
2016 6
2017 5
2018 10
2019 16
2020 6
2021 8
2022 9
2023 7
2024 3

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78 results

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Page 1
The mitochondrial permeability transition pore in Ca2+ homeostasis.
Carraro M, Bernardi P. Carraro M, et al. Cell Calcium. 2023 May;111:102719. doi: 10.1016/j.ceca.2023.102719. Epub 2023 Mar 21. Cell Calcium. 2023. PMID: 36963206 Free article. Review.
Although long-lasting PTP openings have been widely studied, the physiological implications of transient openings (also called "flickering" behavior) are still poorly understood. The flickering activity was suggested to play a role in the regulation of Ca(2+) and ROS homeo …
Although long-lasting PTP openings have been widely studied, the physiological implications of transient openings (also called "flickering" …
Lung ultrasound integrated with clinical assessment for the diagnosis of acute decompensated heart failure in the emergency department: a randomized controlled trial.
Pivetta E, Goffi A, Nazerian P, Castagno D, Tozzetti C, Tizzani P, Tizzani M, Porrino G, Ferreri E, Busso V, Morello F, Paglieri C, Masoero M, Cassine E, Bovaro F, Grifoni S, Maule MM, Lupia E; Study Group on Lung Ultrasound from the Molinette and Careggi Hospitals. Pivetta E, et al. Eur J Heart Fail. 2019 Jun;21(6):754-766. doi: 10.1002/ejhf.1379. Epub 2019 Jan 28. Eur J Heart Fail. 2019. PMID: 30690825 Free article. Clinical Trial.
AIMS: Although acute decompensated heart failure (ADHF) is a common cause of dyspnoea, its diagnosis still represents a challenge. Lung ultrasound (LUS) is an emerging point-of-care diagnostic tool, but its diagnostic performance for ADHF has not been evaluated in randomiz …
AIMS: Although acute decompensated heart failure (ADHF) is a common cause of dyspnoea, its diagnosis still represents a challenge. Lu …
Oncolytic Immunotherapy: Can't Start a Fire Without a Spark.
Muscolini M, Tassone E, Hiscott J. Muscolini M, et al. Cytokine Growth Factor Rev. 2020 Dec;56:94-101. doi: 10.1016/j.cytogfr.2020.07.014. Epub 2020 Aug 4. Cytokine Growth Factor Rev. 2020. PMID: 32826166 Review.
Cancer cells adopt multiple mechanisms to evade and suppress antitumor immune responses, essentially establishing a non-immunogenic ('cold') tumor microenvironment (TME), with poor T-cell infiltration and low mutational burden. Limitations to the efficacy of immunotherapy stil …
Cancer cells adopt multiple mechanisms to evade and suppress antitumor immune responses, essentially establishing a non-immunogenic ('cold') …
Pharmacotherapy for pediatric soft-tissue sarcomas.
Casanova M, Ferrari A. Casanova M, et al. Expert Opin Pharmacother. 2011 Mar;12(4):517-31. doi: 10.1517/14656566.2011.524926. Expert Opin Pharmacother. 2011. PMID: 21306288 Review.
Chemotherapy is usually effective for rhabdomyosarcoma and should be seen as the keystone of its treatment, while non-rhabdomyosarcoma soft-tissue sarcomas are still generally considered scarcely chemosensitive. AREAS COVERED: An overview of current, emerging and possible …
Chemotherapy is usually effective for rhabdomyosarcoma and should be seen as the keystone of its treatment, while non-rhabdomyosarcoma soft- …
The physiological correlates of interpersonal space.
Candini M, Battaglia S, Benassi M, di Pellegrino G, Frassinetti F. Candini M, et al. Sci Rep. 2021 Jan 28;11(1):2611. doi: 10.1038/s41598-021-82223-2. Sci Rep. 2021. PMID: 33510396 Free PMC article.
However, if the SCR is modulated according to participant's preferred IPS is still an open question. To test this hypothesis, we recorded the SCR in healthy participants when a confederate stood in front of them at various distances simulating either an approach or withdra …
However, if the SCR is modulated according to participant's preferred IPS is still an open question. To test this hypothesis, we reco …
Targeted Therapy of Uveal Melanoma: Recent Failures and New Perspectives.
Croce M, Ferrini S, Pfeffer U, Gangemi R. Croce M, et al. Cancers (Basel). 2019 Jun 18;11(6):846. doi: 10.3390/cancers11060846. Cancers (Basel). 2019. PMID: 31216772 Free PMC article. Review.
Direct inhibition of constitutively active oncoproteins deriving from these mutations is still in its infancy in UM, whereas BRAFV600E-targeted therapy has obtained relevant results in cutaneous melanoma. ...
Direct inhibition of constitutively active oncoproteins deriving from these mutations is still in its infancy in UM, whereas BRAFV600 …
Subclinical TRAPS treated with canakinumab.
Amatruda M, Carucci NS, Fede C, Conti G. Amatruda M, et al. Reumatismo. 2021 Aug 3;73(2):131-134. doi: 10.4081/reumatismo.2021.1406. Reumatismo. 2021. PMID: 34342215 Free article.
Therapy with human anti-interleukin 1beta monoclonal antibody, canakinumab, led to disease control and normalization of the inflammatory markers, which are currently still normal. This clinical case supports the need to treat also subclinical TRAPS. ...
Therapy with human anti-interleukin 1beta monoclonal antibody, canakinumab, led to disease control and normalization of the inflammatory mar …
Is There a Standard Adjuvant Therapy for Resected Pancreatic Cancer?
Fenocchio E, Filippi R, Lombardi P, Quarà V, Milanesio M, Aimar G, Leone F, Aglietta M. Fenocchio E, et al. Cancers (Basel). 2019 Oct 12;11(10):0. doi: 10.3390/cancers11101547. Cancers (Basel). 2019. PMID: 31614884 Free PMC article. Review.
Contrary to chemotherapy, the role of adjuvant radiotherapy is still controversial, even in the case of R1 surgery. A randomized trial exploring the role of chemoradiotherapy in this setting is now ongoing in the US (RTOG-0848). ...
Contrary to chemotherapy, the role of adjuvant radiotherapy is still controversial, even in the case of R1 surgery. A randomized tria …
ISG15, a Small Molecule with Huge Implications: Regulation of Mitochondrial Homeostasis.
Albert M, Bécares M, Falqui M, Fernández-Lozano C, Guerra S. Albert M, et al. Viruses. 2018 Nov 13;10(11):629. doi: 10.3390/v10110629. Viruses. 2018. PMID: 30428561 Free PMC article. Review.
Accordingly, the development of efficient antiviral therapies is a major goal and a challenge for the scientific community, as we are still far from understanding the molecular mechanisms that operate after virus infection. ...
Accordingly, the development of efficient antiviral therapies is a major goal and a challenge for the scientific community, as we are sti …
Genome editing in pluripotent stem cells: research and therapeutic applications.
Deleidi M, Yu C. Deleidi M, et al. Biochem Biophys Res Commun. 2016 May 6;473(3):665-74. doi: 10.1016/j.bbrc.2016.02.113. Epub 2016 Feb 27. Biochem Biophys Res Commun. 2016. PMID: 26930470 Review.
In this context, the unlimited proliferation potential and the pluripotent properties of iPSCs may offer advantages for gene targeting approaches. However, many technical and safety issues still need to be addressed before genome-edited iPSCs are translated into the clinic …
In this context, the unlimited proliferation potential and the pluripotent properties of iPSCs may offer advantages for gene targeting appro …
78 results