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Page 1
Cyclodextrin-Based Arsenal for Anti-Cancer Treatments.
Chopra H, Verma R, Kaushik S, Parashar J, Madan K, Bano A, Bhardwaj R, Pandey P, Kumari B, Purohit D, Kumar M, Bhatia S, Rahman MH, Mittal V, Singh I, Kaushik D. Chopra H, et al. Crit Rev Ther Drug Carrier Syst. 2023;40(2):1-41. doi: 10.1615/CritRevTherDrugCarrierSyst.2022038398. Crit Rev Ther Drug Carrier Syst. 2023. PMID: 36734912 Review.
They are generally chosen due to their ability to get self-assembled to form liposomes, nanoparticles, micelles and nano-sponges etc. This review paper describes a birds-eye view of the various CD-based nano-technological approaches applied for the delivery of anti-cancer …
They are generally chosen due to their ability to get self-assembled to form liposomes, nanoparticles, micelles and nano-sponges etc. …
Delivery system for budesonide based on lipid-DNA.
Liu Y, Bos IST, Oenema TA, Meurs H, Maarsingh H, Hirsch AKH. Liu Y, et al. Eur J Pharm Biopharm. 2018 Sep;130:123-127. doi: 10.1016/j.ejpb.2018.06.012. Epub 2018 Jun 14. Eur J Pharm Biopharm. 2018. PMID: 29908939
In this work, we report the use of lipid-DNAA (UU11mer), featuring two hydrophobic alkyl chains and forming micelles at a comparatively low critical micelle concentration, to render budesonide water-soluble with a high loading capacity (LC). ...
In this work, we report the use of lipid-DNAA (UU11mer), featuring two hydrophobic alkyl chains and forming micelles at a comparative …
Diffusion of sodium dodecyl sulfate micelles in agarose gels.
Musnicki WJ, Lloyd NW, Phillips RJ, Dungan SR. Musnicki WJ, et al. J Colloid Interface Sci. 2011 Apr 1;356(1):165-75. doi: 10.1016/j.jcis.2010.12.067. Epub 2010 Dec 28. J Colloid Interface Sci. 2011. PMID: 21272891
Of particular interest were the effects of micelle, gel, and sodium chloride concentration on the micelle diffusivity. ...It was found that the concentration effect is quite strong for charged solutes: at a NaCl concentration of 0.03 M in a 2% agarose gel, in a solu …
Of particular interest were the effects of micelle, gel, and sodium chloride concentration on the micelle diffusivity. ...It w …
Novel biocompatible phosphorylcholine-based self-assembled nanoparticles for drug delivery.
Salvage JP, Rose SF, Phillips GJ, Hanlon GW, Lloyd AW, Ma IY, Armes SP, Billingham NC, Lewis AL. Salvage JP, et al. J Control Release. 2005 May 18;104(2):259-70. doi: 10.1016/j.jconrel.2005.02.003. Epub 2005 Apr 20. J Control Release. 2005. PMID: 15907578
The drug loading capacities of these micelles were evaluated using Orange OT dye as a model compound. The cytotoxicity of the micelles was assessed using an in vitro assay. ...However, these micelles were not stable at physiological pH. In contrast, MPC-DPA d …
The drug loading capacities of these micelles were evaluated using Orange OT dye as a model compound. The cytotoxicity of the mice …
Manufacture of modified milk protein concentrate utilizing injection of carbon dioxide.
Marella C, Salunke P, Biswas AC, Kommineni A, Metzger LE. Marella C, et al. J Dairy Sci. 2015 Jun;98(6):3577-89. doi: 10.3168/jds.2014-8946. Epub 2015 Mar 28. J Dairy Sci. 2015. PMID: 25828657 Free article.
Injection of CO2 resulted in a significant decrease in zeta-potential and a significant increase in the size of the casein micelle. Moreover, RCMPC had a significantly higher solubility after storage at room temperature and at elevated temperature. ...
Injection of CO2 resulted in a significant decrease in zeta-potential and a significant increase in the size of the casein micelle. M …
Nanoprecipitation of polymeric nanoparticle micelles based on 2-methacryloyloxyethyl phosphorylcholine (MPC) with 2-(diisopropylamino)ethyl methacrylate (DPA), for intracellular delivery applications.
Salvage JP, Thom C, Lewis AL, Phillips GJ, Lloyd AW. Salvage JP, et al. J Mater Sci Mater Med. 2015 Mar;26(3):150. doi: 10.1007/s10856-015-5480-9. Epub 2015 Mar 14. J Mater Sci Mater Med. 2015. PMID: 25773229 Free PMC article.
To date, a number of copolymer nanoparticle systems based on 2-methacryloyloxyethyl phosphorylcholine (MPC) with 2-(diisopropylamino)ethyl methacrylate (DPA), displaying biomimetic and pH responsive properties, have been published, however these have been predominately polymersom …
To date, a number of copolymer nanoparticle systems based on 2-methacryloyloxyethyl phosphorylcholine (MPC) with 2-(diisopropylamino)ethyl m …
Measuring local equilibrium flavor distributions in SDS solution using headspace solid-phase microextraction.
Lloyd NW, Kardaras E, Ebeler SE, Dungan SR. Lloyd NW, et al. J Phys Chem B. 2011 Dec 15;115(49):14484-92. doi: 10.1021/jp206984q. Epub 2011 Nov 10. J Phys Chem B. 2011. PMID: 22004271
Headspace concentrations as a function of surfactant concentration were fit to a mass balance to yield the partition coefficient and critical micelle concentration. When the total limonene in the system was low enough that it could be completely dissolved by water in the a …
Headspace concentrations as a function of surfactant concentration were fit to a mass balance to yield the partition coefficient and critica …
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes.
Darwich AS, Margolskee A, Pepin X, Aarons L, Galetin A, Rostami-Hodjegan A, Carlert S, Hammarberg M, Hilgendorf C, Johansson P, Karlsson E, Murphy D, Tannergren C, Thörn H, Yasin M, Mazuir F, Nicolas O, Ramusovic S, Xu C, Pathak SM, Korjamo T, Laru J, Malkki J, Pappinen S, Tuunainen J, Dressman J, Hansmann S, Kostewicz E, He H, Heimbach T, Wu F, Hoft C, Pang Y, Bolger MB, Huehn E, Lukacova V, Mullin JM, Szeto KX, Costales C, Lin J, McAllister M, Modi S, Rotter C, Varma M, Wong M, Mitra A, Bevernage J, Biewenga J, Van Peer A, Lloyd R, Shardlow C, Langguth P, Mishenzon I, Nguyen MA, Brown J, Lennernäs H, Abrahamsson B. Darwich AS, et al. Eur J Pharm Sci. 2017 Jan 1;96:626-642. doi: 10.1016/j.ejps.2016.09.037. Epub 2016 Sep 28. Eur J Pharm Sci. 2017. PMID: 27693299
F(oral) was also underpredicted for acidic compounds, suggesting overestimation of impact of ionisation on permeation, lack of information on intestinal transporters, or underestimation of solubilisation of weak acids due to less than optimal intestinal model pH settings or under …
F(oral) was also underpredicted for acidic compounds, suggesting overestimation of impact of ionisation on permeation, lack of information o …
Retinoic acid-dependent stimulation of 2,2'-azobis(2-amidinopropane)-initiated autoxidation of linoleic acid in sodium dodecyl sulfate micelles: a novel prooxidant effect of retinoic acid.
Freyaldenhoven MA, Lehman PA, Franz TJ, Lloyd RV, Samokyszyn VM. Freyaldenhoven MA, et al. Chem Res Toxicol. 1998 Feb;11(2):102-10. doi: 10.1021/tx970044u. Chem Res Toxicol. 1998. PMID: 9511901
(E)-Retinoic acid (RA) was shown to stimulate the rate of 2,2'-azobis(2-amidinopropane) (AAPH)-initiated autoxidation of linoleic acid (18:2) in sodium dodecyl sulfate (SDS) micelles. RA-dependent stimulation of 18:2 autoxidation was characterized by enhanced rates of diox …
(E)-Retinoic acid (RA) was shown to stimulate the rate of 2,2'-azobis(2-amidinopropane) (AAPH)-initiated autoxidation of linoleic acid (18:2 …
13 results