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Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study.
Dixon-Suen SC, Lewis SJ, Martin RM, English DR, Boyle T, Giles GG, Michailidou K, Bolla MK, Wang Q, Dennis J, Lush M, Investigators A, Ahearn TU, Ambrosone CB, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Augustinsson A, Auvinen P, Beane Freeman LE, Becher H, Beckmann MW, Behrens S, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Bonanni B, Brenner H, Brüning T, Buys SS, Camp NJ, Campa D, Canzian F, Castelao JE, Cessna MH, Chang-Claude J, Chanock SJ, Clarke CL, Conroy DM, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dörk T, Dwek M, Eccles DM, Eliassen AH, Engel C, Eriksson M, Evans DG, Fasching PA, Fletcher O, Flyger H, Fritschi L, Gabrielson M, Gago-Dominguez M, García-Closas M, García-Sáenz JA, Goldberg MS, Guénel P, Gündert M, Hahnen E, Haiman CA, Häberle L, Håkansson N, Hall P, Hamann U, Hart SN, Harvie M, Hillemanns P, Hollestelle A, Hooning MJ, Hoppe R, Hopper J, Howell A, Hunter DJ, Jakubowska A, Janni W, John EM, Jung A, Kaaks R, Keeman R, Kitahara CM, Koutros S, Kraft P, Kristensen VN, Kubelka-Sabit K, Kurian AW, Lacey JV, Lambrechts D, Le Marchand L, Lindblom A, Loibl S, Lubiński J, Mannermaa A, Manoochehri M, Margolin S, Martinez ME, Mavroudis D, Me… See abstract for full author list ➔ Dixon-Suen SC, et al. Br J Sports Med. 2022 Oct;56(20):1157-1170. doi: 10.1136/bjsports-2021-105132. Epub 2022 Sep 6. Br J Sports Med. 2022. PMID: 36328784 Free PMC article.
Short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αCaMKII autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex.
Caffino L, Cassina C, Giannotti G, Orrù A, Moro F, Di Clemente A, Racagni G, Fumagalli F, Cervo L. Caffino L, et al. Int J Neuropsychopharmacol. 2014 Feb;17(2):323-9. doi: 10.1017/S1461145713000916. Epub 2013 Aug 19. Int J Neuropsychopharmacol. 2014. PMID: 23953174 Free article.
Increases in alpha calcium/calmodulin-dependent protein kinase type II (alphaCaMKII) activity in the nucleus accumbens shell has been proposed as a core component in the motivation to self-administer cocaine and in priming-induced drug-seeking. Since cocaine withdrawal pro …
Increases in alpha calcium/calmodulin-dependent protein kinase type II (alphaCaMKII) activity in the nucleus accumbens shell has been propos …
From nonpeptide toward noncarbon protease inhibitors: metallacarboranes as specific and potent inhibitors of HIV protease.
Cígler P, Kozísek M, Rezácová P, Brynda J, Otwinowski Z, Pokorná J, Plesek J, Grüner B, Dolecková-Maresová L, Mása M, Sedlácek J, Bodem J, Kräusslich HG, Král V, Konvalinka J. Cígler P, et al. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15394-9. doi: 10.1073/pnas.0507577102. Epub 2005 Oct 14. Proc Natl Acad Sci U S A. 2005. PMID: 16227435 Free PMC article.
HIV protease (PR) represents a prime target for rational drug design, and protease inhibitors (PI) are powerful antiviral drugs. ...
HIV protease (PR) represents a prime target for rational drug design, and protease inhibitors (PI) are powerful antiviral drugs. ...
Poziotinib for EGFR and HER2 exon 20 insertion mutation in advanced NSCLC: Results from the expanded access program.
Prelaj A, Bottiglieri A, Proto C, Lo Russo G, Signorelli D, Ferrara R, Galli G, De Toma A, Viscardi G, Brambilla M, Lobefaro R, Nichetti F, Manglaviti S, Occhipinti M, Labianca A, Ganzinelli M, Gallucci R, Zilembo N, Greco GF, Torri V, de Braud F, Garassino MC. Prelaj A, et al. Eur J Cancer. 2021 May;149:235-248. doi: 10.1016/j.ejca.2021.02.038. Epub 2021 Apr 2. Eur J Cancer. 2021. PMID: 33820681
Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens.
Sällberg M, Townsend K, Chen M, O'Dea J, Banks T, Jolly DJ, Chang SM, Lee WT, Milich DR. Sällberg M, et al. J Virol. 1997 Jul;71(7):5295-303. doi: 10.1128/JVI.71.7.5295-5303.1997. J Virol. 1997. PMID: 9188598 Free PMC article.
In conclusion, direct injection of retroviral vectors seems to be effective in priming HBc/eAg-specific CD8+ but comparatively inefficient in priming CD4+ Th cells and subsequently specific antibodies. However, the limited HBc/eAg-specific CD4+ cell priming c …
In conclusion, direct injection of retroviral vectors seems to be effective in priming HBc/eAg-specific CD8+ but comparatively ineffi …
Immunogenicity and antigenicity of the ATPase/helicase domain of the hepatitis C virus non-structural 3 protein.
Sällberg M, Zhang ZX, Chen M, Jin L, Birkett A, Peterson DL, Milich DR. Sällberg M, et al. J Gen Virol. 1996 Nov;77 ( Pt 11):2721-8. doi: 10.1099/0022-1317-77-11-2721. J Gen Virol. 1996. PMID: 8922465
The antibody responder hierarchy was reiterated at the T cell level, with the H-2k and the H-2s haplotypes as the best responders. In both the H-2d and H-2k haplotypes ATPase/helicase-primed T cells secreted interleukin 2 and interferon gamma, corroborating observations fr …
The antibody responder hierarchy was reiterated at the T cell level, with the H-2k and the H-2s haplotypes as the best responders. In both t …
[Effect of verapamil on renal function in rats undergoing partial ablation of the kidney mass].
Luquita MG, Weinschelbaum-Jairala S. Luquita MG, et al. Medicina (B Aires). 1990;50(4):330-4. Medicina (B Aires). 1990. PMID: 2130228 Spanish.
Under pentobarbital anesthesia, polyethylene catheters were placed in a carotid artery, jugular vein, urinary bladder and trachea. After the completion of surgery a prime dose of inulin (30 mg.100 g weight-1) was administered. Subsequently a constant dose of 0.5 g.min-1. 1 …
Under pentobarbital anesthesia, polyethylene catheters were placed in a carotid artery, jugular vein, urinary bladder and trachea. After the …