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1993 1
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2003 1
2004 2
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2009 2
2010 1
2011 1
2013 1
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2020 2
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2023 4
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22 results

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Page 1
NRG Oncology/RTOG1205: A Randomized Phase II Trial of Concurrent Bevacizumab and Reirradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma.
Tsien CI, Pugh SL, Dicker AP, Raizer JJ, Matuszak MM, Lallana EC, Huang J, Algan O, Deb N, Portelance L, Villano JL, Hamm JT, Oh KS, Ali AN, Kim MM, Lindhorst SM, Mehta MP. Tsien CI, et al. J Clin Oncol. 2023 Feb 20;41(6):1285-1295. doi: 10.1200/JCO.22.00164. Epub 2022 Oct 19. J Clin Oncol. 2023. PMID: 36260832 Free PMC article. Clinical Trial.
The role of myeloid growth factors in acute leukemia.
Wadleigh M, Stone RM. Wadleigh M, et al. J Natl Compr Canc Netw. 2009 Jan;7(1):84-91. doi: 10.6004/jnccn.2009.0007. J Natl Compr Canc Netw. 2009. PMID: 19176208 Review.
Growth factors have also been used to recruit quiescent leukemia cells into the S-phase of the cell cycle to increase their susceptibility to chemotherapy with the goal to reduce relapse and resistance. Randomized trials evaluating this priming strategy have consistently s …
Growth factors have also been used to recruit quiescent leukemia cells into the S-phase of the cell cycle to increase their susceptibility t …
Central and Peripheral Mechanisms in ApoE4-Driven Diabetic Pathology.
Koren-Iton A, Salomon-Zimri S, Smolar A, Shavit-Stein E, Dori A, Chapman J, Michaelson DM. Koren-Iton A, et al. Int J Mol Sci. 2020 Feb 14;21(4):1289. doi: 10.3390/ijms21041289. Int J Mol Sci. 2020. PMID: 32075060 Free PMC article.
Apolipoprotein E (APOE) epsilon4 gene allele and type 2 diabetes mellitus (T2DM) are prime risk factors for Alzheimer's disease (AD). Despite evidence linking T2DM and apoE4, the mechanism underlying their interaction is yet to be determined. ...
Apolipoprotein E (APOE) epsilon4 gene allele and type 2 diabetes mellitus (T2DM) are prime risk factors for Alzheimer's disease (AD). …
Avoidance of the NLRP3 Inflammasome by the Stealth Pathogen, Coxiella burnetii.
Delaney MA, Hartigh AD, Carpentier SJ, Birkland TP, Knowles DP, Cookson BT, Frevert CW. Delaney MA, et al. Vet Pathol. 2021 Jul;58(4):624-642. doi: 10.1177/0300985820981369. Epub 2020 Dec 28. Vet Pathol. 2021. PMID: 33357072
We found that C. burnetii upregulates pro-IL-1beta and robustly primes NLRP3 inflammasomes via TLR2 and MyD88 signaling. As for wildtype C. burnetii, T4SS-deficient mutants primed and potentiated NLRP3 inflammasomes. ...Mice deficient in NLRP3 or caspase-1 were like …
We found that C. burnetii upregulates pro-IL-1beta and robustly primes NLRP3 inflammasomes via TLR2 and MyD88 signaling. As for wildt …
Training Informal Supporters to Improve Responses to Victim-Survivors of Domestic Violence and Abuse: A Systematic Review.
Schucan Bird K, Stokes N, Rivas C, Tomlinson M, Delve M, Gordon L, Gregory A, Lawrence K, O'Reilly N. Schucan Bird K, et al. Trauma Violence Abuse. 2024 Apr;25(2):1568-1584. doi: 10.1177/15248380231189191. Epub 2023 Aug 31. Trauma Violence Abuse. 2024. PMID: 37649408 Free PMC article. Review.
Using a behavior change model to frame the evidence, the review found that training/educational activities prime informal supporters to respond to victim-survivors, as well as enhancing their capacity and motivation to do so. ...
Using a behavior change model to frame the evidence, the review found that training/educational activities prime informal supporters …
Progestogens versus oestrogens and progestogens for irregular uterine bleeding associated with anovulation.
Hickey M, Higham J, Fraser IS. Hickey M, et al. Cochrane Database Syst Rev. 2000;(2):CD001895. doi: 10.1002/14651858.CD001895. Cochrane Database Syst Rev. 2000. PMID: 10796833 Updated. Review.
In anovulatory DUB with acyclic (irregular) oestrogen production there will be no progesterone withdrawal from oestrogen primed endometrium and so cycles are irregular. Prolonged oestrogen stimulation may cause a build up of endometrium with erratic bleeding as it breaks d …
In anovulatory DUB with acyclic (irregular) oestrogen production there will be no progesterone withdrawal from oestrogen primed endom …
Development and palliative care staff reactions to a sleep regulation educational intervention.
Capezuti E, Zadeh RS, Brigham MA, Dias BA, Kim BC, Lengetti E, Erikson B, Swezey N, Krieger AC. Capezuti E, et al. BMC Palliat Care. 2022 Jan 21;21(1):12. doi: 10.1186/s12904-022-00902-x. BMC Palliat Care. 2022. PMID: 35062933 Free PMC article.
This study reports the content and design development of the PRIME (Program for Improving & Managing Environments for Sleep) sleep online educational intervention as well as the evaluation of the intervention by practicing nurses with a focus on perceived acceptability …
This study reports the content and design development of the PRIME (Program for Improving & Managing Environments for Sleep) slee …
Immunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV.
Van Rompay KK, Abel K, Earl P, Kozlowski PA, Easlick J, Moore J, Buonocore-Buzzelli L, Schmidt KA, Wilson RL, Simon I, Moss B, Rose N, Rose J, Marthas ML. Van Rompay KK, et al. Vaccine. 2010 Feb 10;28(6):1481-92. doi: 10.1016/j.vaccine.2009.11.061. Epub 2009 Dec 6. Vaccine. 2010. PMID: 19995539 Free PMC article.
In an attempt to further increase systemic but also local antiviral immune responses at the site of viral entry, we tested the immunogenicity of different orally administered, replicating vaccines. One group of newborn macaques received an oral prime immunization with a re …
In an attempt to further increase systemic but also local antiviral immune responses at the site of viral entry, we tested the immunogenicit …
Building National Health Security Through a Rapid Self-Assessment and Annual Operational Plan in Uganda, May to September 2021.
Nabatanzi M, Bakiika H, Nabukenya I, Lamorde M, Bukirwa J, Achan MI, Babigumira PA, Nakiire L, Lubanga T, Mbabazi E, Taremwa RB, Mayinja H, Nakinsige A, Makanga DK, Muruta A, Okware S, Komakech I, Makumbi I, Wetaka MM, Kayiwa J, Ocom F, Ario AR, Nabatanzi S, Ojwang J, Boore A, Yemanaberhan R, Lee CT, Obuku E, Stowell D. Nabatanzi M, et al. Health Secur. 2023 Mar-Apr;21(2):130-140. doi: 10.1089/hs.2022.0107. Epub 2023 Mar 20. Health Secur. 2023. PMID: 36940291 Free PMC article.
Quantitative label-free mass spectrometry reveals content and signaling differences between neonatal and adult platelets.
Thom CS, Davenport P, Fazelinia H, Soule-Albridge E, Liu ZJ, Zhang H, Feldman HA, Ding H, Roof J, Spruce LA, Ischiropoulos H, Sola-Visner M. Thom CS, et al. J Thromb Haemost. 2024 May;22(5):1447-1462. doi: 10.1016/j.jtha.2023.12.022. Epub 2023 Dec 30. J Thromb Haemost. 2024. PMID: 38160730
Adult platelets were enriched in phosphorylated GTPase regulatory enzymes and proteins participating in trafficking, which may help prime them for activation and degranulation. Neonatal platelets were enriched in phosphorylated proteins involved in insulin growth factor si …
Adult platelets were enriched in phosphorylated GTPase regulatory enzymes and proteins participating in trafficking, which may help prime …
22 results