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Polyketides from the marine-derived fungus Ascochyta salicorniae and their potential to inhibit protein phosphatases.
Seibert SF, Eguereva E, Krick A, Kehraus S, Voloshina E, Raabe G, Fleischhauer J, Leistner E, Wiese M, Prinz H, Alexandrov K, Janning P, Waldmann H, König GM. Seibert SF, et al. Org Biomol Chem. 2006 Jun 7;4(11):2233-40. doi: 10.1039/b601386d. Epub 2006 May 3. Org Biomol Chem. 2006. PMID: 16729132
Chemical investigation of the marine fungus Ascochyta salicorniae led to the isolation of two new epimeric compounds, ascolactones A (1) and B (2), in addition to the structurally-related polyketides hyalopyrone (3), ascochitine (4), ascochital (5) and ascosalipyrone (6). …
Chemical investigation of the marine fungus Ascochyta salicorniae led to the isolation of two new epimeric compounds, ascolactones A …
An attempt to determine the absolute configuration of two ascolactone stereoisomers with time-dependent density functional theory.
Seibert SF, König GM, Voloshina E, Raabe G, Fleischhauer J. Seibert SF, et al. Chirality. 2006 Jun;18(6):413-8. doi: 10.1002/chir.20266. Chirality. 2006. PMID: 16612802
Two stereoisomers of ascolactone (A, B), natural products with two asymmetric carbon atoms, are isolated from the marine-derived fungus Ascochyta salicorniae. Although these compounds show virtually opposite CD spectra and [alpha]D, 1H- and 13C-NMR data exclude the presenc …
Two stereoisomers of ascolactone (A, B), natural products with two asymmetric carbon atoms, are isolated from the marine-derived fung …