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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1995 1
1996 1
1997 1
1998 3
1999 3
2000 5
2001 3
2002 2
2003 2
2004 2
2005 3
2006 2
2007 2
2008 6
2009 4
2010 3
2011 1
2012 6
2013 4
2014 8
2015 8
2016 10
2017 9
2018 8
2019 11
2020 13
2021 16
2022 20
2023 14
2024 3

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154 results

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Page 1
Bullous pemphigoid: What's ahead?
Furue M, Kadono T. Furue M, et al. J Dermatol. 2016 Mar;43(3):237-40. doi: 10.1111/1346-8138.13207. Epub 2015 Nov 25. J Dermatol. 2016. PMID: 26603373 Review.
Pathogenic autoantibodies preferentially target the non-collagenous 16A domain of collagen XVII (also called BP antigen 2, BPAG2) present in hemidesmosomes. ...Mice that have been genetically manipulated in the pathogenic domain of BPAG2 spontaneously develop subepi …
Pathogenic autoantibodies preferentially target the non-collagenous 16A domain of collagen XVII (also called BP antigen 2, BPAG2) pre …
The ZZ domain of HERC2 is a receptor of arginylated substrates.
Tencer AH, Liu J, Zhu J, Burkholder NT, Zhang Y, Wu W, Strahl BD, Ohta T, Kutateladze TG. Tencer AH, et al. Sci Rep. 2022 Apr 11;12(1):6063. doi: 10.1038/s41598-022-10119-w. Sci Rep. 2022. PMID: 35411094 Free PMC article.
The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protein. Here, we show that the ZZ domain of HERC2 (HERC2(ZZ)) recognizes a mimetic of the Nt-R cargo degradation signal. NMR titration …
The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protei …
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: Prespecified secondary analysis of an ongoing adaptive platform trial (REMAP-CAP) testing interventions within multiple therapeutic domains in which 4869 critically ill adult patients with COVID-19 were enrolled between March 9, 2020, and …
DESIGN, SETTING, AND PARTICIPANTS: Prespecified secondary analysis of an ongoing adaptive platform trial (REMAP-CAP) testing interventions w …
HECW2-related disorder in four Japanese patients.
Yanagishita T, Hirade T, Shimojima Yamamoto K, Funatsuka M, Miyamoto Y, Maeda M, Yanagi K, Kaname T, Nagata S, Nagata M, Ishihara Y, Miyashita Y, Asano Y, Sakata Y, Kosaki K, Yamamoto T. Yanagishita T, et al. Am J Med Genet A. 2021 Oct;185(10):2895-2902. doi: 10.1002/ajmg.a.62363. Epub 2021 May 28. Am J Med Genet A. 2021. PMID: 34047014
The HECT, C2, and WW domain containing E3 ubiquitin protein ligase 2 gene (HECW2) is involved in protein ubiquitination. Several genes associated with protein ubiquitination have been linked to neurodevelopmental disorders. ...
The HECT, C2, and WW domain containing E3 ubiquitin protein ligase 2 gene (HECW2) is involved in protein ubiquitination …
The contribution of IL-17 to the development of autoimmunity in psoriasis.
Furue M, Kadono T. Furue M, et al. Innate Immun. 2019 Aug;25(6):337-343. doi: 10.1177/1753425919852156. Epub 2019 May 24. Innate Immun. 2019. PMID: 31122103 Free PMC article. Review.
These auto-Ags include LL-37, A disintegrin and metalloprotease domain containing thrombospondin type 1 motif-like 5 (ADAMTSL5), and keratin 17. ...
These auto-Ags include LL-37, A disintegrin and metalloprotease domain containing thrombospondin type 1 motif-like 5 (ADAMTSL5), and …
Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
REMAP-CAP Writing Committee for the REMAP-CAP Investigators; Bradbury CA, Lawler PR, Stanworth SJ, McVerry BJ, McQuilten Z, Higgins AM, Mouncey PR, Al-Beidh F, Rowan KM, Berry LR, Lorenzi E, Zarychanski R, Arabi YM, Annane D, Beane A, van Bentum-Puijk W, Bhimani Z, Bihari S, Bonten MJM, Brunkhorst FM, Buzgau A, Buxton M, Carrier M, Cheng AC, Cove M, Detry MA, Estcourt LJ, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Huang DT, Horvat CM, Hunt BJ, Ichihara N, Lamontagne F, Leavis HL, Linstrum KM, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, Middeldorp S, Montgomery SK, Morpeth SC, Murthy S, Neal MD, Nichol AD, Parke RL, Parker JC, Reyes LF, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Singh V, Tolppa T, Turgeon AF, Turner AM, van de Veerdonk FL, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Webb SA, Gordon AC. REMAP-CAP Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2022 Apr 5;327(13):1247-1259. doi: 10.1001/jama.2022.2910. JAMA. 2022. PMID: 35315874 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: In an ongoing adaptive platform trial (REMAP-CAP) testing multiple interventions within multiple therapeutic domains, 1557 critically ill adult patients with COVID-19 were enrolled between October 30, 2020, and June 23, 2021, from 105 sit …
DESIGN, SETTING, AND PARTICIPANTS: In an ongoing adaptive platform trial (REMAP-CAP) testing multiple interventions within multiple therapeu …
NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis.
Nagasaka M, Ou SI. Nagasaka M, et al. Trends Cancer. 2022 Mar;8(3):242-258. doi: 10.1016/j.trecan.2021.11.003. Epub 2022 Jan 5. Trends Cancer. 2022. PMID: 34996744 Free article. Review.
Neuregulins (NRGs) are a family of six related physiological ligands all containing a receptor-binding epidermal growth factor (EGF)-like domain that mediate their binding to cellular receptors. Neuregulin-1 (NRG1) is the main physiological ligand to HER3. ...
Neuregulins (NRGs) are a family of six related physiological ligands all containing a receptor-binding epidermal growth factor (EGF)-like …
Spontaneous Remission of Thrombospondin Type-1 Domain-Containing-Associated Membranous Nephropathy.
Watanabe S, Suzuki T, Han W, Nakata M, Koitabashi K, Ichikawa D, Kamijo-Ikemori A, Koike J, Shibagaki Y. Watanabe S, et al. Intern Med. 2021 Oct 1;60(19):3125-3128. doi: 10.2169/internalmedicine.6413-20. Epub 2021 Apr 12. Intern Med. 2021. PMID: 33840692 Free PMC article.
However, there are scarce reports of spontaneous remission of thrombospondin type-1 domain-containing 7A (THSD7A)-associated membranous nephropathy. A 64-year-old female presented with nephrotic syndrome and edema of the lower extremities. ...
However, there are scarce reports of spontaneous remission of thrombospondin type-1 domain-containing 7A (THSD7A)-associated membrano …
Insights into VPS13 properties and function reveal a new mechanism of eukaryotic lipid transport.
Leonzino M, Reinisch KM, De Camilli P. Leonzino M, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Oct;1866(10):159003. doi: 10.1016/j.bbalip.2021.159003. Epub 2021 Jul 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 34216812 Free PMC article. Review.
The occurrence of protein mediated lipid transfer between intracellular membranes has been known since the late 1960's. ...Typically, they comprise a lipid harboring module thought to shuttle back and forth between the two adjacent bilayers. Recently, however, studies of t …
The occurrence of protein mediated lipid transfer between intracellular membranes has been known since the late 1960's. ...Typically, …
154 results