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Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis.
Maddali MV, Churpek M, Pham T, Rezoagli E, Zhuo H, Zhao W, He J, Delucchi KL, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Laffey JG, Bellani G, Calfee CS, Sinha P; LUNG SAFE Investigators and the ESICM Trials Group. Maddali MV, et al. Lancet Respir Med. 2022 Apr;10(4):367-377. doi: 10.1016/S2213-2600(21)00461-6. Epub 2022 Jan 10. Lancet Respir Med. 2022. PMID: 35026177 Free PMC article.
Performance of the primary model was similar when using exclusively EHR-derived predictors compared with manually curated predictors (AUC=0.88 [95% CI 0.81-0.94] vs 0.92 [0.88-0.97]). ...
Performance of the primary model was similar when using exclusively EHR-derived predictors compared with manually curated predictors …
Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis.
Kumar S, Singh J, Rattan S, DiMarino AJ, Cohen S, Jimenez SA. Kumar S, et al. Aliment Pharmacol Ther. 2017 Apr;45(7):883-898. doi: 10.1111/apt.13963. Epub 2017 Feb 9. Aliment Pharmacol Ther. 2017. PMID: 28185291 Free PMC article. Review.
To summarise existing knowledge regarding the cardinal clinical gastrointestinal manifestations of SSc and its pathogenesis, emphasising recent investigations that may be valuable in identifying potentially novel therapeutic targets. METHODS: Electronic (PubMed/Medline) and ma
To summarise existing knowledge regarding the cardinal clinical gastrointestinal manifestations of SSc and its pathogenesis, emphasising rec …
A behavioral intervention to improve obstetrical care.
Althabe F, Buekens P, Bergel E, Belizán JM, Campbell MK, Moss N, Hartwell T, Wright LL; Guidelines Trial Group. Althabe F, et al. N Engl J Med. 2008 May 1;358(18):1929-40. doi: 10.1056/NEJMsa071456. N Engl J Med. 2008. PMID: 18450604 Free article. Clinical Trial.
METHODS: We randomly assigned 19 hospitals in Argentina and Uruguay to receive a multifaceted behavioral intervention (including selection of opinion leaders, interactive workshops, training of manual skills, one-on-one academic detailing visits with hospital birth attenda …
METHODS: We randomly assigned 19 hospitals in Argentina and Uruguay to receive a multifaceted behavioral intervention (including selection o …
Quantification of Very Low Concentrations of Leukocyte Suspensions In Vitro by High-Frequency Ultrasound.
Jimenez X, Shukla SK, Ortega I, Illana FJ, Castro-González C, Marti-Fuster B, Butterworth I, Arroyo M, Anthony B, Elvira L. Jimenez X, et al. Ultrasound Med Biol. 2016 Jul;42(7):1568-73. doi: 10.1016/j.ultrasmedbio.2016.01.027. Epub 2016 Apr 7. Ultrasound Med Biol. 2016. PMID: 27067281
Here we show that high frequency ultrasound (HFUS) can detect CSF WBC in vitro in concentrations relevant to meningitis diagnosis with a much finer precision than gold standard manual counting in a Fuchs-Rosenthal chamber. WBC concentrations in a mock CSF model, in the ran …
Here we show that high frequency ultrasound (HFUS) can detect CSF WBC in vitro in concentrations relevant to meningitis diagnosis with a muc …
A lung graph model for the radiological assessment of chronic thromboembolic pulmonary hypertension in CT.
Jimenez-Del-Toro O, Dicente Cid Y, Platon A, Hachulla AL, Lador F, Poletti PA, Müller H. Jimenez-Del-Toro O, et al. Comput Biol Med. 2020 Oct;125:103962. doi: 10.1016/j.compbiomed.2020.103962. Epub 2020 Aug 14. Comput Biol Med. 2020. PMID: 32841766
An accuracy of 0.76 was obtained with the proposed texture analysis, and was then compared to the visual assessment of CT findings, manually identified by a team of three expert radiologists, commonly associated with pulmonary hypertension. This graph-based score combined …
An accuracy of 0.76 was obtained with the proposed texture analysis, and was then compared to the visual assessment of CT findings, manua
Comparison of automated devices UX-2000 and SediMAX/AutionMax for urine samples screening: A multicenter Spanish study.
Sánchez-Mora C, Acevedo D, Porres MA, Chaqués AM, Zapardiel J, Gallego-Cabrera A, López JM, Maesa JM. Sánchez-Mora C, et al. Clin Biochem. 2017 Aug;50(12):714-718. doi: 10.1016/j.clinbiochem.2017.02.005. Epub 2017 Feb 7. Clin Biochem. 2017. PMID: 28188739
Test strip results were subjected to concordance evaluation. Agreement was assessed by Cohen's weighted kappa for multinomial results. Sensitivity (SE) and specificity (SP) were calculated. ...However, it needs some improvements such as an image module in order to d …
Test strip results were subjected to concordance evaluation. Agreement was assessed by Cohen's weighted kappa for multinomial …
An overview of the BioCreative 2012 Workshop Track III: interactive text mining task.
Arighi CN, Carterette B, Cohen KB, Krallinger M, Wilbur WJ, Fey P, Dodson R, Cooper L, Van Slyke CE, Dahdul W, Mabee P, Li D, Harris B, Gillespie M, Jimenez S, Roberts P, Matthews L, Becker K, Drabkin H, Bello S, Licata L, Chatr-aryamontri A, Schaeffer ML, Park J, Haendel M, Van Auken K, Li Y, Chan J, Muller HM, Cui H, Balhoff JP, Chi-Yang Wu J, Lu Z, Wei CH, Tudor CO, Raja K, Subramani S, Natarajan J, Cejuela JM, Dubey P, Wu C. Arighi CN, et al. Database (Oxford). 2013 Jan 17;2013:bas056. doi: 10.1093/database/bas056. Print 2013. Database (Oxford). 2013. PMID: 23327936 Free PMC article.
The performance results from this evaluation indicate that some of the systems were able to improve efficiency of curation by speeding up the curation task significantly (1.7- to 2.5-fold) over manual curation. In addition, some of the systems were able to improve annotati …
The performance results from this evaluation indicate that some of the systems were able to improve efficiency of curation by speeding up th …
The impact of cognitive behavioral group training on event-free survival in patients with myocardial infarction: the ENRICHD experience.
Saab PG, Bang H, Williams RB, Powell LH, Schneiderman N, Thoresen C, Burg M, Keefe F; ENRICHD Investigators. Saab PG, et al. J Psychosom Res. 2009 Jul;67(1):45-56. doi: 10.1016/j.jpsychores.2009.01.015. Epub 2009 Apr 1. J Psychosom Res. 2009. PMID: 19539818 Free PMC article. Clinical Trial.
Depression was diagnosed using modified Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria; low perceived social support was determined by the ENRICHD Social Support Instrument. ...
Depression was diagnosed using modified Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria; low …
Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
Leung W, Shaffer CD, Reed LK, Smith ST, Barshop W, Dirkes W, Dothager M, Lee P, Wong J, Xiong D, Yuan H, Bedard JE, Machone JF, Patterson SD, Price AL, Turner BA, Robic S, Luippold EK, McCartha SR, Walji TA, Walker CA, Saville K, Abrams MK, Armstrong AR, Armstrong W, Bailey RJ, Barberi CR, Beck LR, Blaker AL, Blunden CE, Brand JP, Brock EJ, Brooks DW, Brown M, Butzler SC, Clark EM, Clark NB, Collins AA, Cotteleer RJ, Cullimore PR, Dawson SG, Docking CT, Dorsett SL, Dougherty GA, Downey KA, Drake AP, Earl EK, Floyd TG, Forsyth JD, Foust JD, Franchi SL, Geary JF, Hanson CK, Harding TS, Harris CB, Heckman JM, Holderness HL, Howey NA, Jacobs DA, Jewell ES, Kaisler M, Karaska EA, Kehoe JL, Koaches HC, Koehler J, Koenig D, Kujawski AJ, Kus JE, Lammers JA, Leads RR, Leatherman EC, Lippert RN, Messenger GS, Morrow AT, Newcomb V, Plasman HJ, Potocny SJ, Powers MK, Reem RM, Rennhack JP, Reynolds KR, Reynolds LA, Rhee DK, Rivard AB, Ronk AJ, Rooney MB, Rubin LS, Salbert LR, Saluja RK, Schauder T, Schneiter AR, Schulz RW, Smith KE, Spencer S, Swanson BR, Tache MA, Tewilliager AA, Tilot AK, VanEck E, Villerot MM, Vylonis MB, Watson DT, Wurzler JA, Wysocki LM, Yalamanchili M, Zaborowicz MA, Eme… See abstract for full author list ➔ Leung W, et al. G3 (Bethesda). 2015 Mar 4;5(5):719-40. doi: 10.1534/g3.114.015966. G3 (Bethesda). 2015. PMID: 25740935 Free PMC article.
To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F elements and euchromatic domains from the Muller D element. ...
To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the ge …