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Targets for medical therapy in obesity.
Baretić M. Baretić M. Dig Dis. 2012;30(2):168-72. doi: 10.1159/000336672. Epub 2012 Jun 20. Dig Dis. 2012. PMID: 22722433 Review.
There is a large group of drugs used for other indications with weight loss effects, e.g. incretin mimetics or analogues used in the treatment of diabetes type 2, topiramate used as an anticonvulsant, and fluoxetine and sertraline used in the treatment of depression....
There is a large group of drugs used for other indications with weight loss effects, e.g. incretin mimetics or analogues used in the …
Venetoclax Use in Paediatric Haemato-Oncology Centres in Poland: A 2022 Survey.
Bobeff K, Pastorczak A, Urbanska Z, Balwierz W, Juraszewska E, Wachowiak J, Derwich K, Samborska M, Kalwak K, Dachowska-Kalwak I, Laguna P, Malinowska I, Smalisz K, Gozdzik J, Oszer A, Urbanski B, Zdunek M, Szczepanski T, Mlynarski W, Janczar S. Bobeff K, et al. Children (Basel). 2023 Apr 19;10(4):745. doi: 10.3390/children10040745. Children (Basel). 2023. PMID: 37189994 Free PMC article.
Venetoclax, the best established BH3-mimetic, is a practice-changing proapoptotic drug in blood cancers in adults. ...Importantly, patients with CR included subtypes expected to show venetoclax vulnerability, such as poor-prognosis ALL with TCF::HLF fusion. We believe BH3- …
Venetoclax, the best established BH3-mimetic, is a practice-changing proapoptotic drug in blood cancers in adults. ...Importantly, pa …
A Synthetic Virus-Like Particle Streptococcal Vaccine Candidate Using B-Cell Epitopes from the Proline-Rich Region of Pneumococcal Surface Protein A.
Tamborrini M, Geib N, Marrero-Nodarse A, Jud M, Hauser J, Aho C, Lamelas A, Zuniga A, Pluschke G, Ghasparian A, Robinson JA. Tamborrini M, et al. Vaccines (Basel). 2015 Oct 16;3(4):850-74. doi: 10.3390/vaccines3040850. Vaccines (Basel). 2015. PMID: 26501327 Free PMC article.
A further step might involve focusing the host humoral immune response onto protective protein epitopes using as immunogens structurally optimized epitope mimetics. One approach to deliver such epitope mimetics to the immune system is through the use of synthetic vi …
A further step might involve focusing the host humoral immune response onto protective protein epitopes using as immunogens structurally opt …