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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 1
1983 1
1985 2
1987 3
1988 2
1989 1
1990 3
1991 2
1992 1
1996 1
1997 1
1999 4
2001 1
2003 1
2004 2
2005 2
2007 3
2008 1
2009 2
2010 3
2011 3
2013 4
2014 2
2015 2
2016 9
2017 1
2018 3
2019 1
2021 3
2022 1
2023 1
2024 0

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62 results

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Page 1
Assessing Cytoskeletal Destruction During Pyroptosis.
Davis MA, Gale M Jr. Davis MA, et al. Methods Mol Biol. 2023;2641:179-188. doi: 10.1007/978-1-0716-3040-2_15. Methods Mol Biol. 2023. PMID: 37074651
Instead, we previously demonstrated that in vitro, pyroptotic cells do not in fact lyse. We also demonstrated that calpain cleaves vimentin, leading to loss of intermediate filaments, which in turn makes cells fragile and susceptible to rupture by extrinsic pressure. ...
Instead, we previously demonstrated that in vitro, pyroptotic cells do not in fact lyse. We also demonstrated that calpain cleaves vi …
Targeting the Bacterial Division Protein FtsZ.
Hurley KA, Santos TM, Nepomuceno GM, Huynh V, Shaw JT, Weibel DB. Hurley KA, et al. J Med Chem. 2016 Aug 11;59(15):6975-98. doi: 10.1021/acs.jmedchem.5b01098. Epub 2016 Mar 10. J Med Chem. 2016. PMID: 26756351 Review.
Cells depleted of or lacking functional FtsZ do not divide and grow into long filaments that eventually lyse. FtsZ has been studied extensively as a target for antibacterial development. ...
Cells depleted of or lacking functional FtsZ do not divide and grow into long filaments that eventually lyse. FtsZ has been studied e …
Escaping Death: How Cancer Cells and Infected Cells Resist Cell-Mediated Cytotoxicity.
Tuomela K, Ambrose AR, Davis DM. Tuomela K, et al. Front Immunol. 2022 Mar 23;13:867098. doi: 10.3389/fimmu.2022.867098. eCollection 2022. Front Immunol. 2022. PMID: 35401556 Free PMC article. Review.
Cytotoxic T lymphocytes and Natural Killer cells can directly lyse malignant or infected cells in at least two ways: granule-mediated cytotoxicity, involving perforin and granzyme B, or death receptor-mediated cytotoxicity, involving the death receptor ligands, tumour necr …
Cytotoxic T lymphocytes and Natural Killer cells can directly lyse malignant or infected cells in at least two ways: granule-mediated …
Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy.
Luna JI, Grossenbacher SK, Murphy WJ, Canter RJ. Luna JI, et al. Expert Opin Biol Ther. 2017 Mar;17(3):313-324. doi: 10.1080/14712598.2017.1271874. Epub 2016 Dec 23. Expert Opin Biol Ther. 2017. PMID: 27960589 Free PMC article. Review.
Areas covered: Natural killer (NK) cells have long been known for their ability to reject allogeneic hematopoietic stem cells, and there are increasing data demonstrating that NK cells can selectively identify and lyse CSCs. The authors review the current knowledge of CSCs …
Areas covered: Natural killer (NK) cells have long been known for their ability to reject allogeneic hematopoietic stem cells, and there are …
Pouring petrol on the flames: Using oncolytic virotherapies to enhance tumour immunogenicity.
Teijeira Crespo A, Burnell S, Capitani L, Bayliss R, Moses E, Mason GH, Davies JA, Godkin AJ, Gallimore AM, Parker AL. Teijeira Crespo A, et al. Immunology. 2021 Aug;163(4):389-398. doi: 10.1111/imm.13323. Epub 2021 Mar 28. Immunology. 2021. PMID: 33638871 Free PMC article. Review.
Oncolytic viruses possess the ability to infect, replicate and lyse malignantly transformed tumour cells. This oncolytic activity amplifies the therapeutic advantage and induces a form of immunogenic cell death, characterized by increased CD8 (+) T-cell infiltration into t …
Oncolytic viruses possess the ability to infect, replicate and lyse malignantly transformed tumour cells. This oncolytic activity amp …
Biosynthesis of the [FeFe] hydrogenase H-cluster via a synthetic [Fe(II)(CN)(CO)2(cysteinate)]- complex.
Britt RD, Rauchfuss TB. Britt RD, et al. Dalton Trans. 2021 Sep 21;50(36):12386-12391. doi: 10.1039/d1dt02258j. Dalton Trans. 2021. PMID: 34545884 Free PMC article. Review.
We have proposed that HydG is a bifunctional enzyme that uses S-adenosylmethione (SAM) bound to a [4Fe-4S] cluster to lyse tyrosine via a transient 5'-deoxyadenosyl radical to produce CO and CN ligands to a unique cysteine-chelated Fe(II) that is linked to a second [4Fe-4S …
We have proposed that HydG is a bifunctional enzyme that uses S-adenosylmethione (SAM) bound to a [4Fe-4S] cluster to lyse tyrosine v …
Controlled trials comparing reteplase with alteplase and streptokinase in patients with acute myocardial infarction.
Amsterdam EA. Amsterdam EA. Pharmacotherapy. 1996 Sep-Oct;16(5 Pt 2):137S-140S. Pharmacotherapy. 1996. PMID: 8888101 Review.
Although the ability of a thrombolytic agent to lyse a clot has been recognized for over 50 years, it was not until recently that this form of therapy was used to treat acute myocardial infarction. ...
Although the ability of a thrombolytic agent to lyse a clot has been recognized for over 50 years, it was not until recently that thi …
Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells.
Carisey AF, Mace EM, Saeed MB, Davis DM, Orange JS. Carisey AF, et al. Curr Biol. 2018 Feb 19;28(4):489-502.e9. doi: 10.1016/j.cub.2017.12.044. Epub 2018 Feb 1. Curr Biol. 2018. PMID: 29398219 Free PMC article.
Natural killer (NK) cells are innate immune effectors that lyse virally infected and tumorigenic cells through the formation of an immunological synapse. ...
Natural killer (NK) cells are innate immune effectors that lyse virally infected and tumorigenic cells through the formation of an im …
A penicillin-binding protein inhibits selection of colistin-resistant, lipooligosaccharide-deficient Acinetobacter baumannii.
Boll JM, Crofts AA, Peters K, Cattoir V, Vollmer W, Davies BW, Trent MS. Boll JM, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6228-E6237. doi: 10.1073/pnas.1611594113. Epub 2016 Sep 28. Proc Natl Acad Sci U S A. 2016. PMID: 27681618 Free PMC article.
Unique glycolipids called lipopolysaccharide/lipooligosaccharide (LPS/LOS) are enriched in the cell-surface monolayer of the outer membrane and promote antimicrobial resistance. Colistin, which targets the lipid A domain of LPS/LOS to lyse the cell, is the last-line treatm …
Unique glycolipids called lipopolysaccharide/lipooligosaccharide (LPS/LOS) are enriched in the cell-surface monolayer of the outer membrane …
62 results