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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1975 1
1982 1
1983 1
1987 1
1988 3
1989 1
1991 3
1992 3
1994 4
1995 3
1996 3
1997 4
1998 2
1999 2
2000 3
2001 2
2002 3
2003 5
2004 4
2005 5
2006 10
2007 3
2008 4
2009 8
2010 5
2011 9
2012 5
2013 6
2014 8
2015 8
2016 14
2017 13
2018 11
2019 11
2020 26
2021 18
2022 17
2023 12
2024 6

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227 results

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Page 1
Rescuing cardiac automaticity in L-type Cav1.3 channelopathies and beyond.
Mesirca P, Bidaud I, Mangoni ME. Mesirca P, et al. J Physiol. 2016 Oct 15;594(20):5869-5879. doi: 10.1113/JP270678. Epub 2016 Aug 2. J Physiol. 2016. PMID: 27374078 Free PMC article. Review.
In recent years an increasing number of mutations affecting ion channels involved in sino-atrial automaticity have been reported to underlie inheritable SSS. L-type Ca(v) 1.3 channels play a major role in the generation and regulation of sino-atrial pacemaker activity and …
In recent years an increasing number of mutations affecting ion channels involved in sino-atrial automaticity have been reported to underlie …
Regulation of gene transcription by voltage-gated L-type calcium channel, Cav1.3.
Lu L, Sirish P, Zhang Z, Woltz RL, Li N, Timofeyev V, Knowlton AA, Zhang XD, Yamoah EN, Chiamvimonvat N. Lu L, et al. J Biol Chem. 2015 Feb 20;290(8):4663-4676. doi: 10.1074/jbc.M114.586883. Epub 2014 Dec 23. J Biol Chem. 2015. PMID: 25538241 Free PMC article.
Cav1.3 L-type Ca(2+) channel is known to be highly expressed in neurons and neuroendocrine cells. ...M., Koschak, A., Lieb, A., Gebhart, M., Dafinger, C., Nurnberg, G., Ali, A., Ahmad, I., Sinnegger-Brauns, M. J., Brandt, N., Engel, J., Mangoni, M. E., Farooq, M., K …
Cav1.3 L-type Ca(2+) channel is known to be highly expressed in neurons and neuroendocrine cells. ...M., Koschak, A., Lieb, A., Gebha …
Channelopathies of voltage-gated L-type Cav1.3/alpha(1D) and T-type Cav3.1/alpha(1G) Ca(2+) channels in dysfunction of heart automaticity.
Torrente AG, Mesirca P, Bidaud I, Mangoni ME. Torrente AG, et al. Pflugers Arch. 2020 Jul;472(7):817-830. doi: 10.1007/s00424-020-02421-1. Epub 2020 Jun 29. Pflugers Arch. 2020. PMID: 32601767 Free article. Review.
Several families of ion channels are involved in the generation and regulation of the heart automaticity. Among those, voltage-gated L-type Cav1.3 (alpha1D) and T-type Cav3.1 (alpha1G) Ca(2+) channels play important roles in the spontaneous activity of pacemaker cells. ...
Several families of ion channels are involved in the generation and regulation of the heart automaticity. Among those, voltage-gated L
Systematic Review and Meta-Analysis of the Effect of Statins on Circulating E-Selectin, L-Selectin, and P-Selectin.
Zinellu A, Mangoni AA. Zinellu A, et al. Biomedicines. 2021 Nov 17;9(11):1707. doi: 10.3390/biomedicines9111707. Biomedicines. 2021. PMID: 34829936 Free PMC article. Review.
We conducted a systematic review and meta-analysis of the effects of statins on the circulating cell adhesion molecules E-Selectin, L-Selectin, and P-Selectin. A literature search was conducted in PubMed, Web of Science, and Scopus, from inception to July 2021. ...In 61 st …
We conducted a systematic review and meta-analysis of the effects of statins on the circulating cell adhesion molecules E-Selectin, L
Serum L-arginine and endogenous methylarginine concentrations predict irritable bowel syndrome in adults: A nested case-control study.
McEvoy MA, Attia JR, Oldmeadow C, Holliday E, Smith WT, Mangoni AA, Peel R, Hancock SJ, Walker MM, Talley NJ. McEvoy MA, et al. United European Gastroenterol J. 2021 Sep;9(7):809-818. doi: 10.1002/ueg2.12137. Epub 2021 Aug 25. United European Gastroenterol J. 2021. PMID: 34431615 Free PMC article.

[Correction added on 18 September 2021, after first online publication: In the preceding sentence, the value (p > 0.05) has been changed to (p < 0.05)]. Similar results were found for IBS subtypes. Higher serum L-arginine concentration had the strongest association w

[Correction added on 18 September 2021, after first online publication: In the preceding sentence, the value (p > 0.05) has been changed …
First-in-Class Cyclic Temporin L Analogue: Design, Synthesis, and Antimicrobial Assessment.
Bellavita R, Casciaro B, Di Maro S, Brancaccio D, Carotenuto A, Falanga A, Cappiello F, Buommino E, Galdiero S, Novellino E, Grossmann TN, Mangoni ML, Merlino F, Grieco P. Bellavita R, et al. J Med Chem. 2021 Aug 12;64(15):11675-11694. doi: 10.1021/acs.jmedchem.1c01033. Epub 2021 Jul 23. J Med Chem. 2021. PMID: 34296619 Free PMC article.
Herein, we aimed at increasing the alpha-helicity content of temporin L, an isoform of an intriguing class of linear antimicrobial peptides (AMPs), endowed with a wide antimicrobial spectrum, by the employment of diverse side-chain tethering strategies, including lactam, 1 …
Herein, we aimed at increasing the alpha-helicity content of temporin L, an isoform of an intriguing class of linear antimicrobial pe …
Heart rate reduction after genetic ablation of L-type Ca(v)1.3 channels induces cardioprotection against ischemia-reperfusion injury.
Delgado-Betancourt V, Chinda K, Mesirca P, Barrère C, Covinhes A, Gallot L, Vincent A, Bidaud I, Kumphune S, Nargeot J, Piot C, Wickman K, Mangoni ME, Barrère-Lemaire S. Delgado-Betancourt V, et al. Front Cardiovasc Med. 2023 Aug 1;10:1134503. doi: 10.3389/fcvm.2023.1134503. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37593151 Free PMC article.
Developing drugs that selectively reduce heart rate by inhibiting ion channels involved in heart rate control could provide more clinical benefits. The Ca(v)1.3-mediated L-type Ca(2+) current (I(Cav1.3)) play important roles in the generation of heart rate. ...OBJECTIVE: W …
Developing drugs that selectively reduce heart rate by inhibiting ion channels involved in heart rate control could provide more clinical be …
Selegiline for Alzheimer's disease.
Birks J, Flicker L. Birks J, et al. Cochrane Database Syst Rev. 2003;(1):CD000442. doi: 10.1002/14651858.CD000442. Cochrane Database Syst Rev. 2003. PMID: 12535396 Review.
SEARCH STRATEGY: The Cochrane Dementia and Cognitive Impairment Group Register of Clinical Trials, was searched using the terms 'selegiline', 'l-deprenyl', "eldepryl" and "monamine oxidase inhibitor-B". MEDLINE, PsycLIT and EMBASE electronic databases were searched with th …
SEARCH STRATEGY: The Cochrane Dementia and Cognitive Impairment Group Register of Clinical Trials, was searched using the terms 'selegiline' …
Determination of Strong-Phase Parameters in DK_{S,L}^{0}pi^{+}pi^{-}.
Ablikim M, Achasov MN, Adlarson P, Ahmed S, Albrecht M, Alekseev M, Ambrose D, Amoroso A, An FF, An Q, Anita, Bai Y, Bakina O, Baldini Ferroli R, Balossino I, Ban Y, Begzsuren K, Bennett JV, Berger N, Bertani M, Bettoni D, Bianchi F, Biernat J, Bloms J, Boyko I, Briere RA, Cai H, Cai X, Calcaterra A, Cao GF, Cao N, Cetin SA, Chai J, Chang JF, Chang WL, Chelkov G, Chen DY, Chen G, Chen HS, Chen J, Chen JC, Chen ML, Chen SJ, Chen YB, Cheng W, Cibinetto G, Cossio F, Cui XF, Dai HL, Dai JP, Dai XC, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Fan JZ, Fang J, Fang SS, Fang Y, Farinelli R, Fava L, Feldbauer F, Felici G, Feng CQ, Fritsch M, Fu CD, Fu Y, Gao Q, Gao XL, Gao Y, Gao Y, Gao YG, Gao Z, Garillon B, Garzia I, Gersabeck EM, Gilman A, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu LM, Gu MH, Gu S, Gu YT, Guo AQ, Guo LB, Guo RP, Guo YP, Guskov A, Han S, Hao XQ, Harris FA, He KL, Heinsius FH, Held T, Heng YK, Himmelreich M, Hou YR, Hou ZL, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huesken N, Hussain T, Ikegami Andersson W, Imoehl W, Irshad M, Ji Q, Ji QP, Ji XB, Ji XL… See abstract for full author list ➔ Ablikim M, et al. Phys Rev Lett. 2020 Jun 19;124(24):241802. doi: 10.1103/PhysRevLett.124.241802. Phys Rev Lett. 2020. PMID: 32639796
We report the most precise measurements to date of the strong-phase parameters between D^{0} and D[over ]^{0} decays to K_{S,L}^{0}pi^{+}pi^{-} using a sample of 2.93 fb^{-1} of e^{+}e^{-} annihilation data collected at a center-of-mass energy of 3.773 GeV with the BESIII …
We report the most precise measurements to date of the strong-phase parameters between D^{0} and D[over ]^{0} decays to K_{S,L}^{0}pi …
L-Type Ca(v)1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells.
Louradour J, Bortolotti O, Torre E, Bidaud I, Lamb N, Fernandez A, Le Guennec JY, Mangoni ME, Mesirca P. Louradour J, et al. Cells. 2022 Mar 25;11(7):1114. doi: 10.3390/cells11071114. Cells. 2022. PMID: 35406677 Free PMC article.
Recent studies showed that beta-adrenergic stimulation can initiate spontaneous firing in dormant SANC, though this mechanism is not entirely understood. METHODS: To investigate the role of L-type Ca(v)1.3 Ca(2+) channels in the adrenergic regulation of automaticity in dor …
Recent studies showed that beta-adrenergic stimulation can initiate spontaneous firing in dormant SANC, though this mechanism is not entirel …
227 results