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jian zhang yang
(1,735 results)?
Discovery of a Highly Potent and Selective Dual PROTAC Degrader of CDK12 and CDK13.
J Med Chem. 2022 Aug 25;65(16):11066-11083. doi: 10.1021/acs.jmedchem.2c00384. Epub 2022 Aug 8.
J Med Chem. 2022.
PMID: 35938508
Free PMC article.
Targeted inhibition of ZAK ameliorates renal interstitial fibrosis.
Shu S, Liu H, Yang J, Tang H, Li H, Liu Z, Zhou M, Zhu F, Hu Z, Ding K, Lu X, Nie J.
Shu S, et al. Among authors: yang j.
Transl Res. 2022 Aug;246:49-65. doi: 10.1016/j.trsl.2022.03.002. Epub 2022 Mar 8.
Transl Res. 2022.
PMID: 35276386
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Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.
Yang J, Shibu MA, Kong L, Luo J, BadrealamKhan F, Huang Y, Tu ZC, Yun CH, Huang CY, Ding K, Lu X.
Yang J, et al.
J Med Chem. 2020 Mar 12;63(5):2114-2130. doi: 10.1021/acs.jmedchem.9b00664. Epub 2019 Jun 17.
J Med Chem. 2020.
PMID: 31244114
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CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality.
Tien JC, Chang Y, Zhang Y, Chou J, Cheng Y, Wang X, Yang J, Mannan R, Shah P, Wang XM, Todd AJ, Eyunni S, Cheng C, Rebernick RJ, Xiao L, Bao Y, Neiswender J, Brough R, Pettitt SJ, Cao X, Miner SJ, Zhou L, Wu YM, Labanca E, Wang Y, Parolia A, Cieslik M, Robinson DR, Wang Z, Feng FY, Lord CJ, Ding K, Chinnaiyan AM.
Tien JC, et al. Among authors: yang j.
bioRxiv [Preprint]. 2024 Mar 21:2024.03.20.585990. doi: 10.1101/2024.03.20.585990.
bioRxiv. 2024.
PMID: 38562774
Free PMC article.
Preprint.
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Optimization of isoxazoline amide benzoxaboroles for identification of a development candidate as an oral long acting animal ectoparasiticide.
Zhang YK, Plattner JJ, Easom EE, Akama T, Zhou Y, White WH, Defauw JM, Winkle JR, Balko TW, Cao J, Ge Z, Yang J.
Zhang YK, et al. Among authors: yang j.
Bioorg Med Chem Lett. 2016 Jul 1;26(13):3182-3186. doi: 10.1016/j.bmcl.2016.04.093. Epub 2016 May 7.
Bioorg Med Chem Lett. 2016.
PMID: 27210432
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