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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, … See abstract for full author list ➔ Klionsky DJ, et al. Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Autophagy. 2016. PMID: 26799652 Free PMC article. No abstract available.
Differential expression of defense/stress-related marker proteins in leaves of a unique rice blast lesion mimic mutant (blm).
Jung YH, Rakwal R, Agrawal GK, Shibato J, Kim JA, Lee MO, Choi PK, Jung SH, Kim SH, Koh HJ, Yonekura M, Iwahashi H, Jwa NS. Jung YH, et al. J Proteome Res. 2006 Oct;5(10):2586-98. doi: 10.1021/pr060092c. J Proteome Res. 2006. PMID: 17022630
We analyzed a unique rice (Oryza sativa L.) blast lesion mimic (blm) mutant for differentially expressed proteins in leaves of one- and two-week-old seedlings manifesting the lesion mimic phenotype. Gel-based one- and two-dimensional electrophoresis (1- and 2-DGE) was perf …
We analyzed a unique rice (Oryza sativa L.) blast lesion mimic (blm) mutant for differentially expressed proteins in leaves of one- a …
Characterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediates.
Jung H, Lee JA, Choi S, Lee H, Ahn B. Jung H, et al. PLoS One. 2014 Jul 18;9(7):e102402. doi: 10.1371/journal.pone.0102402. eCollection 2014. PLoS One. 2014. PMID: 25036527 Free PMC article.
BLM is a RecQ DNA helicase that, with interacting proteins, is able to dissolve various DNA structures including double Holliday junctions. A BLM ortholog, him-6, has been identified in Caenorhabditis elegans, but little is known about its enzymatic activities or it …
BLM is a RecQ DNA helicase that, with interacting proteins, is able to dissolve various DNA structures including double Holliday junc …
Phenomenology of the trickster archetype, U.S. electoral politics and the Black Lives Matter movement.
Vaughan AG. Vaughan AG. J Anal Psychol. 2021 Jun;66(3):695-718. doi: 10.1111/1468-5922.12698. J Anal Psychol. 2021. PMID: 34231898
This paper examines the Black Lives Matter (BLM) movement in cultural, historical and relational contexts at the intersection of the U.S. ...The paper concludes with a brief note on the social activism of Fair Fight Georgia and the integration of its agenda into the BLM …
This paper examines the Black Lives Matter (BLM) movement in cultural, historical and relational contexts at the intersection of the …
Elevation of IL-6 and IL-33 Levels in Serum Associated with Lung Fibrosis and Skeletal Muscle Wasting in a Bleomycin-Induced Lung Injury Mouse Model.
Shieh JM, Tseng HY, Jung F, Yang SH, Lin JC. Shieh JM, et al. Mediators Inflamm. 2019 Mar 27;2019:7947596. doi: 10.1155/2019/7947596. eCollection 2019. Mediators Inflamm. 2019. PMID: 31049028 Free PMC article.
Pulmonary fibrosis is a chronic and progressive interstitial lung disease characterized by the dysregulated deposition of the extracellular matrix (ECM) with the destruction of normal tissue, resulting in end-stage organ failure. BLM-induced fibrosis is one of several diff …
Pulmonary fibrosis is a chronic and progressive interstitial lung disease characterized by the dysregulated deposition of the extracellular …
Fucoxanthin inhibits profibrotic protein expression in vitro and attenuates bleomycin-induced lung fibrosis in vivo.
Ma SY, Park WS, Lee DS, Choi G, Yim MJ, Lee JM, Jung WK, Park SG, Seo SK, Park SJ, Han IY, Choi YH, Choi IW. Ma SY, et al. Eur J Pharmacol. 2017 Sep 15;811:199-207. doi: 10.1016/j.ejphar.2017.06.022. Epub 2017 Jun 19. Eur J Pharmacol. 2017. PMID: 28642129
We also investigated the effects of Fx on inflammation and fibrosis in bleomycin (BLM)-induced pulmonary fibrosis mouse model. We observed that Fx inhibited the TGF-beta1-induced expression of alpha-SMA, type 1 collagen, fibronectin, and IL-6 in HPFs. ...Collagen contracti …
We also investigated the effects of Fx on inflammation and fibrosis in bleomycin (BLM)-induced pulmonary fibrosis mouse model. We obs …
Prevalence and clinical implications of germline predisposition gene mutations in patients with acute myeloid leukemia.
Kim B, Yun W, Lee ST, Choi JR, Yoo KH, Koo HH, Jung CW, Kim SH. Kim B, et al. Sci Rep. 2020 Aug 31;10(1):14297. doi: 10.1038/s41598-020-71386-z. Sci Rep. 2020. PMID: 32868804 Free PMC article.
Among 180 patients, germline predisposition mutations were identified in 13 patients (13/180, 7.2%, eight adults and five children). Germline mutations of BLM, BRCA1, BRCA2, CTC1, DDX41, ERCC4, ERCC6, FANCI, FANCM, PALB2, and SBDS were identified. ...
Among 180 patients, germline predisposition mutations were identified in 13 patients (13/180, 7.2%, eight adults and five children). Germlin …
The rice (Oryza sativa) blast lesion mimic mutant, blm, may confer resistance to blast pathogens by triggering multiple defense-associated signaling pathways.
Jung YH, Lee JH, Agrawal GK, Rakwal R, Kim JA, Shim JK, Lee SK, Jeon JS, Koh HJ, Lee YH, Iwahashi H, Jwa NS. Jung YH, et al. Plant Physiol Biochem. 2005 Apr;43(4):397-406. doi: 10.1016/j.plaphy.2005.03.002. Epub 2005 Apr 7. Plant Physiol Biochem. 2005. PMID: 15907692
The rice blm displayed spontaneous necrotic lesion formation on the leaves during development under long-day condition and temperature shift from 28 to 24 degrees C in the absence of obvious stress/disease, and provided us with a highly reproducible and convenient experime …
The rice blm displayed spontaneous necrotic lesion formation on the leaves during development under long-day condition and temperatur …
IL-1-IL-17 Signaling Axis Contributes to Fibrosis and Inflammation in Two Different Murine Models of Systemic Sclerosis.
Park MJ, Moon SJ, Lee EJ, Jung KA, Kim EK, Kim DS, Lee JH, Kwok SK, Min JK, Park SH, Cho ML. Park MJ, et al. Front Immunol. 2018 Jul 10;9:1611. doi: 10.3389/fimmu.2018.01611. eCollection 2018. Front Immunol. 2018. PMID: 30042768 Free PMC article.
The purpose of this study was to investigate whether IL-17 plays a pathophysiological role in SSc in two different murine models of SSc. METHODS: Bleomycin (BLM)-induced fibrosis and chronic graft-versus-host disease (cGVHD) models were used. ...RESULTS: IL-1 receptor anta …
The purpose of this study was to investigate whether IL-17 plays a pathophysiological role in SSc in two different murine models of SSc. MET …
Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosis.
Lee SH, Jang AS, Kim YE, Cha JY, Kim TH, Jung S, Park SK, Lee YK, Won JH, Kim YH, Park CS. Lee SH, et al. Respir Res. 2010 Feb 8;11(1):16. doi: 10.1186/1465-9921-11-16. Respir Res. 2010. PMID: 20137099 Free PMC article.
METHODS: BMDMSCs were transferred 4 days after BLM inhalation. Wet/dry ratio, bronchoalveolar lavage cell profiles, histologic changes and deposition of collagen were analyzed. ...CONCLUSION: Systemic transfer of BMDMSCs effectively reduced the BLM-induced lung inju …
METHODS: BMDMSCs were transferred 4 days after BLM inhalation. Wet/dry ratio, bronchoalveolar lavage cell profiles, histologic change …
13 results