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Activation of c-jun N-terminal kinase/stress-activated protein kinase and the decreased ratio of Bcl-2 to Bax are associated with the auto-oxidized dopamine-induced apoptosis in PC12 cells.
Kang CD, Jang JH, Kim KW, Lee HJ, Jeong CS, Kim CM, Kim SH, Chung BS. Kang CD, et al. Neurosci Lett. 1998 Oct 30;256(1):37-40. doi: 10.1016/s0304-3940(98)00751-4. Neurosci Lett. 1998. PMID: 9832211
Auto-oxidized-dopamine induced DNA fragmentation and activation of c-jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) faster and stronger than dopamine. ...
Auto-oxidized-dopamine induced DNA fragmentation and activation of c-jun N-terminal kinase (JNK)/stress-activated protein kinase (SAP …
Downregulation of JNK/SAPK activity is associated with the cross-resistance to P-glycoprotein-unrelated drugs in multidrug-resistant FM3A/M cells overexpressing P-glycoprotein.
Kang CD, Ahn BK, Jeong CS, Kim KW, Lee HJ, Yoo SD, Chung BS, Kim SH. Kang CD, et al. Exp Cell Res. 2000 Apr 10;256(1):300-7. doi: 10.1006/excr.2000.4807. Exp Cell Res. 2000. PMID: 10739677
In the present study, cross-drug resistance in multidrug-resistant (MDR) cells, which overexpress P-glycoprotein (Pgp), a mdr1 gene product, against Pgp-unrelated drugs, and its relevance to c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) activity were …
In the present study, cross-drug resistance in multidrug-resistant (MDR) cells, which overexpress P-glycoprotein (Pgp), a mdr1 gene product, …
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